Mapping the genome of Plasmodium falciparum on the drug-like chemical space reveals novel anti-malarial targets and potential drug leads

Autor: Irene Kouskoumvekaki, Damian R. Plichta, Kasper P. Jensen, Gianni Panagiotou

Publikováno v: Jensen, K, Plichta, D R, Panagiotou, G & Kouskoumvekaki, I 2012, ' Mapping the genome of Plasmodium falciparum on the drug-like chemical space reveals novel anti-malarial targets and potential drug leads ', Molecular BioSystems, vol. 8, no. 6, pp. 1678-1685 . https://doi.org/10.1039/c2mb00008c

The parasite Plasmodium falciparum is the main agent responsible for malaria. In this study, we exploited a recently published chemical library from GlaxoSmithKline (GSK) that had previously been confirmed to inhibit parasite growth of the wild type

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::088fd7084a6d223f48e061f5ef5f313b
https://pubmed.ncbi.nlm.nih.gov/22446744