Zobrazeno 1 - 10
of 786
pro vyhledávání: '"depotentiation"'
Akademický článek
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Autor:
Ming Zhang, Hongbing Wang
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
The type 1 and 8 adenylyl cyclase (ADCY1 and ADCY8) exclusively account for Ca2+-stimulated cyclic AMP (cAMP) production and regulate activity-dependent synaptic modification. In this study, we examined distinct forms of synaptic plasticity in the hi
Externí odkaz:
https://doaj.org/article/e1a56eb30b314c71baf35e5cd0f00887
Publikováno v:
Genel Tıp Dergisi, Vol 31, Iss 4, Pp 369-374 (2021)
Önceki çalışma bulgularımız, normal tiroit hormon düzeylerinin sinaptik plastisitenin göstergeleri olan uzun dönemli güçlenme (UDG) ve uzun dönemli baskılanma (UDB) yanıtları arasındaki dengenin oluşmasında rol oynayabileceğini gö
Externí odkaz:
https://doaj.org/article/ebe848a0e2a2427dad48bcf1cbfbe854
Autor:
Song, Ge1, Zhu, Qianqian1, Han, Fubing1, Liu, Shuai1, Zhao, Chenyang1, Zhou, Yu1 yuzhou7310@gmail.com
Publikováno v:
Neuroscience Letters. Jan2018, Vol. 662, p71-76. 6p.
Akademický článek
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Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-13 (2019)
Abstract Many mouse models of Alzheimer’s disease (AD) exhibit impairments in hippocampal long-term-potentiation (LTP), seemingly corroborating the strong correlation between synaptic loss and cognitive decline reported in human studies. In other A
Externí odkaz:
https://doaj.org/article/8368c7c16d2b4c169e58d858f4711a8b
Autor:
Pojeong Park, Thomas M. Sanderson, Zuner A. Bortolotto, John Georgiou, Min Zhuo, Bong-Kiun Kaang, Graham L. Collingridge
Publikováno v:
Molecular Brain, Vol 12, Iss 1, Pp 1-5 (2019)
Abstract Theta-burst stimulation (TBS) induces short-term potentiation (STP) plus two types of transcriptionally-independent forms of long-term potentiation (LTP), termed LTP1 and LTP2. We have compared the susceptibility of these three types of syna
Externí odkaz:
https://doaj.org/article/b37950e94b1343fd95b24658078690e9
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
In nature, animals need to adapt to constant changes in their environment. Learning and memory are cognitive capabilities that allow this to happen. Extinction, the reduction of a certain behavior or learning previously established, refers to a very
Externí odkaz:
https://doaj.org/article/61dc9c08b34e4b40aa63fd01c3a64d8f
Autor:
Valeria Calabrese, Anna Di Maio, Gioia Marino, Antonella Cardinale, Giuseppina Natale, Arianna De Rosa, Federica Campanelli, Maria Mancini, Francesco Napolitano, Luigi Avallone, Paolo Calabresi, Alessandro Usiello, Veronica Ghiglieri, Barbara Picconi
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
Levodopa (L-DOPA) treatment is the main gold-standard therapy for Parkinson disease (PD). Besides good antiparkinsonian effects, prolonged use of this drug is associated to the development of involuntary movements known as L-DOPA-induced dyskinesia (
Externí odkaz:
https://doaj.org/article/a7602896de9f424fb37861e0572fc994
Autor:
Yang Bai, Miao Li, Yanmei Zhou, Lei Ma, Qian Qiao, Wanling Hu, Wei Li, Zachary Patrick Wills, Wen-Biao Gan
Publikováno v:
Molecular Neurodegeneration, Vol 12, Iss 1, Pp 1-15 (2017)
Abstract Background Alzheimer’s disease (AD) is characterized by amyloid deposition, tangle formation as well as synapse loss. Synaptic abnormalities occur early in the pathogenesis of AD. Identifying early synaptic abnormalities and their underlyi
Externí odkaz:
https://doaj.org/article/7a924d09f8b749d2aee61762c03c021c