Zobrazeno 1 - 10
of 161
pro vyhledávání: '"deoxyribonucleic acid damage"'
Autor:
Ali JN Duabil, Christian R Cooper, Esraa Aldujaily, Sarah ER Halford, Sandra Hirschberg, Sidath D Katugampola, George DD Jones
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 4, Iss 6, Pp 1210-1226 (2023)
Aim: In response to DNA damage the serine/threonine-specific protein kinase checkpoint kinase 1 (CHK1) is activated allowing cells to enter S phase (S) and G2 phase (G2) cell-cycle arrest. CHK1 inhibitors are expected to prevent cells from entering s
Externí odkaz:
https://doaj.org/article/ec7ed657492f40f28f2f810abf6cf0d2
Publikováno v:
Journal of Clinical and Diagnostic Research, Vol 17, Iss 10, Pp 05-10 (2023)
Introduction: Baseline expression of p16INK4a characterises cellular senescence. Similarly, the measurement of γ-GammaH2AX (γ-H2AX) foci levels in cells provides a reliable method for quantification of Deoxyribonucleic Acid (DNA) damage. Aim: To
Externí odkaz:
https://doaj.org/article/de821b0a6dfe4ed89def3556751fc576
Autor:
Jose Solomon Raj, J Suganthy, B S Timothy Peace, Selvamani Backianathan, I Rabi Raja Singh, Reka Karuppusami, Christhunesa Soundararajan Christudass, Raja Solomon
Publikováno v:
Journal of Medical Physics, Vol 48, Iss 2, Pp 146-153 (2023)
Purpose: This study aims to investigate the use of the neutral comet assay to assess deoxyribonucleic acid (DNA) damage in lymphocytes exposed to high doses of radiation. Materials and Methods: The research was conducted by obtaining informed consent
Externí odkaz:
https://doaj.org/article/d09016335c064c37aef64f4163504927
Autor:
Ricardo Toipa Lopes, Margarida Gonçalo
Publikováno v:
Revista da Sociedade Portuguesa de Dermatologia e Venereologia, Vol 80, Iss 1 (2022)
Fluoroquinolones are photosensitizing drugs in humans, as they can enhance effects of ultraviolet A (UVA) radiation on the skin. UVA causes lesions both to deoxyribonucleic acid and other cellular organelles by Type I and Type II reactions (major and
Externí odkaz:
https://doaj.org/article/b854635921c64be4b9414f87692d0ca6
Akademický článek
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Changes in Deoxyribonucleic Acid Methylation Contribute to the Pathophysiology of Multiple Sclerosis
Autor:
Naiara Celarain, Jordi Tomas-Roig
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system characterized by loss of coordination, weakness, dysfunctions in bladder capacity, bowel movement, and cognitive impairment. Thus, the disease leads to a significant socio
Externí odkaz:
https://doaj.org/article/86dc6fcb120349dd97d9d46445bc7cb0
Publikováno v:
Biomedical Journal, Vol 38, Iss 2, Pp 117-124 (2015)
Chronic airway inflammatory diseases are life-threatening conditions, including bronchial asthma, chronic obstructive pulmonary disease (COPD), and so on. However, as the disease etiology remains largely unclear, current treatments that target chroni
Externí odkaz:
https://doaj.org/article/a546f9efe0f5465f9f19f23edf2cb616
Akademický článek
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Publikováno v:
Journal of Research in Medical Sciences, Vol 19, Iss 6, Pp 542-548 (2014)
Background: Chemical pollutants found in industrial environments can cause chronic genotoxicity in vulnerable individuals during the long-term exposure. The primary purpose of the present study was to assess the deoxyribonucleic acid (DNA) damage cau
Externí odkaz:
https://doaj.org/article/e02b564bd97b4c0fac71c1d1db48e7d5
Akademický článek
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