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of 47
pro vyhledávání: '"dengue envelope protein"'
Akademický článek
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Autor:
Nafsoon Rahman, Shiho Miura, Mami Okawa, Md. Golam Kibria, Mohammad Monirul Islam, Yutaka Kuroda
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
We previously demonstrated that a protein’s immunogenicity could be substantially increased by attaching a hydrophobic solubility controlling peptide tag (SCP-tag) producing small sub-visible aggregates. Here, we report the oligomerization of Dengu
Externí odkaz:
https://doaj.org/article/abf827425eb2415c92d9301a0537d7fe
Publikováno v:
Frontiers in Medical Technology, Vol 3 (2021)
Dengue infections still have a tremendous impact on public health systems in most countries in tropical and subtropical regions. The disease is systemic and dynamic with broad range of manifestations, varying from mild symptoms to severe dengue (Deng
Externí odkaz:
https://doaj.org/article/8e2a742cc4614eea92ccd3127b7638c3
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Abnormal immune responses and cytokine storm are involved in the development of severe dengue, a life-threatening disease with high mortality. Dengue virus-induced neutrophil NETosis response is associated with cytokine storm; while the role of viral
Externí odkaz:
https://doaj.org/article/47104554f4a042f7876e709edc7721e1
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Typically occurring during secondary dengue virus (DENV) infections, dengue hemorrhagic fever (DHF) causes abnormal immune responses, as well as endothelial vascular dysfunction, for which the responsible viral factor remains unclear. During peak vir
Externí odkaz:
https://doaj.org/article/673008b8f14f4c0684e2a5a8e537d005
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Recombinant proteins are an attractive choice as a safe alternative to traditional live attenuated vaccines. However, most small-size proteins are poorly immunogenic, and adjuvants, whose mode of action remain to be fully clarified, are needed for in
Externí odkaz:
https://doaj.org/article/ab68973c4eb74d1c8b6330ea223d6de6
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9270
Dengue hemorrhagic fever (DHF) is a severe form of dengue virus (DENV) infection that can lead to abnormal immune responses, endothelial vascular dysfunction, and hemorrhage pathogenesis. The virion-associated envelope protein domain III (EIII) is th
Akademický článek
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Autor:
Jannatul Aklima, Sawaros Onchaiya, Tomonori Saotome, Punitha Velmurugan, Taihei Motoichi, Jannatul Naima, Yutaka Kuroda, Yoshihiro Ohta
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 17; Pages: 9881
Protein quality control is essential for cellular homeostasis. In this study, we examined the effect of improperly folded proteins that do not form amyloid fibrils on mitochondria, which play important roles in ATP production and cell death. First, w
Akademický článek
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