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of 827
pro vyhledávání: '"dendritic spike"'
Akademický článek
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Publikováno v:
Frontiers in Physics, Vol 8 (2020)
Dendritic spikes facilitate neuronal computation and they have been reported to occur in various regions of the dendritic tree of cortical neurons. Spikes that occur only on a select few branches are particularly difficult to analyze especially in co
Externí odkaz:
https://doaj.org/article/c3014bc9231b4798846e1e7dfba3c0a2
Publikováno v:
eLife, Vol 7 (2018)
Long-term potentiation (LTP) of synaptic responses is essential for hippocampal memory function. Perforant-path (PP) synapses on hippocampal granule cells (GCs) contribute to the formation of associative memories, which are considered the cellular co
Externí odkaz:
https://doaj.org/article/39acce6fbac0456b8aaaa10d7fa87850
Autor:
Nicola Masala, Martin Pofahl, André N Haubrich, Khondker Ushna Sameen Islam, Negar Nikbakht, Maryam Pasdarnavab, Kirsten Bohmbach, Kunihiko Araki, Fateme Kamali, Christian Henneberger, Kurtulus Golcuk, Laura A Ewell, Sandra Blaess, Tony Kelly, Heinz Beck
Publikováno v:
Brain 146(6), 2399-2417 (2023). doi:10.1093/brain/awac455
Memory deficits are a debilitating symptom of epilepsy, but little is known about mechanisms underlying cognitive deficits. Here, we describe a Na+ channel-dependent mechanism underlying altered hippocampal dendritic integration, degraded place codin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbeaa2b524ee2be384bba35a7ff7c581
https://pub.dzne.de/record/258241
https://pub.dzne.de/record/258241
Akademický článek
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Akademický článek
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Autor:
Nicolangelo Iannella, Thomas Launey
Publikováno v:
Frontiers in Computational Neuroscience, Vol 11 (2017)
The ability for cortical neurons to adapt their input/output characteristics and information processing capabilities ultimately relies on the interplay between synaptic plasticity, synapse location, and the nonlinear properties of the dendrite. Colle
Externí odkaz:
https://doaj.org/article/479f9bfe36214ee2894b53c36d9b581b
Autor:
Roberta Leone, Federico Brandalise, Fritjof Helmchen, Stefano Carta, Anthony Holtmaat, Urs Gerber
N-methyl- d -aspartate receptor-mediated ( spikes can be causally linked to the induction of synaptic long-term potentiation (LTP) in hippocampal and cortical pyramidal cells. However, it is unclear if they regulate plasticity at a local or global sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd8e087dfc2351162873e69feef1471d
https://doi.org/10.5167/uzh-212725
https://doi.org/10.5167/uzh-212725
Autor:
Erik De Schutter, Yunliang Zang
Publikováno v:
The Journal of Neuroscience
Neuronal firing patterns are crucial to underpin circuit level behaviors. In cerebellar Purkinje cells (PCs), both spike rates and pauses are used for behavioral coding, but the cellular mechanisms causing code transitions remain unknown. We use a we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9392231a95f1ca52603eb18d1f8fdaff
http://europepmc.org/articles/PMC7939085
http://europepmc.org/articles/PMC7939085
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance An active pyramidal cell model, constrained by physiological and anatomical data, was used to simulate dendritic integration in vivo. The model shows that small numbers of strong excitatory synapses can trigger dendritic Na+ and NMDA spi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99e381299fe83c34cd8efcd827612486
https://pubmed.ncbi.nlm.nih.gov/34301882
https://pubmed.ncbi.nlm.nih.gov/34301882