Zobrazeno 1 - 10
of 217
pro vyhledávání: '"dendrite development"'
Autor:
Erin N. Lottes, Feyza Ciger, Shatabdi Bhattacharjee, Emily A. Timmins, Benoit Tete, Tommy Tran, Jais Matta, Atit A. Patel, Daniel N. Cox
Publikováno v:
Cells, Vol 13, Iss 12, p 1029 (2024)
The development of cell-type-specific dendritic arbors is integral to the proper functioning of neurons within their circuit networks. In this study, we examine the regulatory relationship between the cytosolic chaperonin CCT, key insulin pathway gen
Externí odkaz:
https://doaj.org/article/e965ea5123ea44cebe87ec4c2ddc1557
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 14 (2023)
The GRIN2B-related neurodevelopmental disorder is a rare disease caused by mutations in the GRIN2B gene, which encodes the GluN2B subunit of NMDA receptors. Most individuals with GRIN2B-related neurodevelopmental disorder present with intellectual di
Externí odkaz:
https://doaj.org/article/a2e39ed0c7724de9a6e63e84c5db66b2
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-15 (2020)
Abstracts Proper dendrite morphogenesis and neuronal migration are crucial for cerebral cortex development and neural circuit formation. In this study, we sought to determine if the histone deacetylase HDAC6 plays a role in dendrite development and n
Externí odkaz:
https://doaj.org/article/2911b02a769e46c08932fb7048981ee9
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/451a1882acec494e8aa8457eb8414999
Akademický článek
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Akademický článek
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Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Mutations in GRIN2B, which encodes the GluN2B subunit of NMDA receptors, lead to autism spectrum disorders (ASD), but the pathophysiological mechanisms remain unclear. Recently, we showed that a GluN2B variant that is associated with severe ASD (GluN
Externí odkaz:
https://doaj.org/article/13f05bb7077043d88c24bdd62496ff55
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Somatosensory neurons (SSNs) densely innervate our largest organ, the skin, and shape our experience of the world, mediating responses to sensory stimuli including touch, pressure, and temperature. Historically, epidermal contributions to somatosensa
Externí odkaz:
https://doaj.org/article/beced03f25d64d64b4e43dd9e6fb8b35
Publikováno v:
Cell Reports, Vol 33, Iss 3, Pp 108269- (2020)
Summary: Eukaryotic mRNAs are 5′ end capped with a 7-methylguanosine, which is important for processing and translation of mRNAs. Cap methyltransferase 1 (CMTR1) catalyzes 2′-O-ribose methylation of the first transcribed nucleotide (N1 2′-O-Me)
Externí odkaz:
https://doaj.org/article/62072538263a4dac914fb3917585f521
Growth cone-localized microtubule organizing center establishes microtubule orientation in dendrites
Autor:
Xing Liang, Marcela Kokes, Richard D Fetter, Maria Danielle Sallee, Adrian W Moore, Jessica L Feldman, Kang Shen
Publikováno v:
eLife, Vol 9 (2020)
A polarized arrangement of neuronal microtubule arrays is the foundation of membrane trafficking and subcellular compartmentalization. Conserved among both invertebrates and vertebrates, axons contain exclusively ‘plus-end-out’ microtubules while
Externí odkaz:
https://doaj.org/article/53ff6b0e9f694e06bf5a746857c9ab01