Pre-operative stereotactic radiosurgery and peri-operative dexamethasone for resectable brain metastases: a two-arm pilot study evaluating clinical outcomes and immunological correlates

Autor: Caroline S. Jansen, Meghana S. Pagadala, Maria A. Cardenas, Roshan S. Prabhu, Subir Goyal, Chengjing Zhou, Prasanthi Chappa, BaoHan T. Vo, Chengyu Ye, Benjamin Hopkins, Jim Zhong, Adam Klie, Taylor Daniels, Maedot Admassu, India Green, Neil T. Pfister, Stewart G. Neill, Jeffrey M. Switchenko, Nataliya Prokhnevska, Kimberly B. Hoang, Mylin A. Torres, Suzanna Logan, Jeffrey J. Olson, Edjah K. Nduom, Luke del Balzo, Kirtesh Patel, Stuart H. Burri, Anthony L. Asher, Scott Wilkinson, Ross Lake, Aparna H. Kesarwala, Kristin A. Higgins, Pretesh Patel, Vishal Dhere, Adam G. Sowalsky, Hannah Carter, Mohammad K. Khan, Haydn Kissick, Zachary S. Buchwald

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)

Abstract Enhancing the efficacy of immunotherapy in brain metastases (BrM) requires an improved understanding of the immune composition of BrM and how this is affected by radiation and dexamethasone. Our two-arm pilot study (NCT04895592) allocated 26

Externí odkaz: https://doaj.org/article/f2e15d60d8c7479ea6d0d2f87a5326a2

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National, longitudinal NASCITA birth cohort study: prevalence of overweight at 12 months of age in children born healthy

Autor: Antonio Clavenna, Massimo Cartabia, Maurizio Bonati, Federico Marchetti, Giorgio Tamburlini, Antonio Addis, Michele Valente, Rita Campi, Stefania Manetti, Valeria Carraro, Sergio Conti Nibali, Renato Sansone, Patrizia Rogari, Annalisa Campomori, Luca De Fiore, Renata Bortolus, Sergio Cattani, Cristiana Piloni, Valeria Renzetti, Rosario Cavallo, Gherardo Rapisardi, Giacomo Toffol, Vicenza Briscioli, Carla Cafaro, Cristoforo Cocchiara, Isodiana Crupi, Patrizia Del Balzo, Laura Dell’edera, Chiara Di Francesco, Alberto Ferrando, Francesca Grassa, Chiara Guidoni, Claudio Mangialavori, Stefano Marinoni, Francesca Marongiu, Fausta Matera, Paolo Moretti, Laura Olimpi, Angela Pasinato, Ilaria Porro, Ippolita Roncoroni, Raffaella Schiro’, Patrizia Seppia, Federica Zanetto, Anna Aloisio, Elisabetta Anedda, Giuliana Apuzzo, Giovanna Argo, Anna Armenio, Emanuela Ballerini, Monica Benedetti, Daniela Bertoli, Stefano Bollettini, Chiara Bottalico, Aurora Bottiglieri, Vincenza Briscioli, Antonella Bruno, Laura Brusadin, Mariantonietta Caiazzo, Patrizia Calamita, Miriana Callegari, Rosaria Cambria, Maria Cristina Cantù, Domenico Capomolla, Anna Caracciolo, Maria Concetta Carbone, Gaetano Carrassi, Maria Laura Cartiglia, Sara Casagranda, Ornella Castiglione, Rosario Salvatore Cavallo, Teresa Cazzato, Maria Angela Cazzuffi, Jennifer Chiarolanza, Rosaria China, Nicoletta Cimadamore, Roberto Cionini, Cristina Ciuffo, Damiano Colazzo, Anna Maria Costantini, Claudio Cravidi, Marialuisa Criscione, Rita D’Agostino, Daniela Danieli, Luigi De Carlo, Marina De Sanctis, Giuseppina De Santes, Gian Piero Del Bono, Maria Elisabetta Di Pietro, Maria Chiara Dini, Paolo Fiammengo, Micaela Foco, Maria Teresa Fonte, Maria Frigeri, Andrea Galvagno, Matteo Gaudino, Stefania Genoni, Silvia Girotto, Gianluca Gornati, Marta Gozzi, Enrica Heritier, Antonella Lavagetto, Raffaele Limauro, Alessandra Magnelli, Maria Gabriella Maiolino, Monica Malventano, Silvia Marchi, Natale Maresca, Federico Marolla, Agata Martinelli, Chiara Martinez, Nicoletta Mascarello, Carla Matiotti, Elisabetta Mazzucchi, Donatella Moggia, Manuela Musetti, Paolo Nardini, Alberto Neri, Patrizia Neri, Flavia Nicoloso, Laura Maria Olimpi, Giancarlo Ottonello, Giacinta Padula, Paolo Maria Paganuzzi, Rosanna Palazzi, Alessandra Palmero, Maria Chiara Parisini, Giovannina Pastorelli, Marilena Pavoni, Lucia Peccarisi, Antonella Pellacani, Cristina Perrera, Michela Picciotti, Ivo Picotto, Tiziana Piunti, Francesca Preziosi, Giuseppe Primavera, Miriam Prodi, Maria Letizia Rabbone, Innocenza Rafele, Laura Reali, Franziska Stefanie Rempp, Ada Riundi, Paolo Rosas, Annarita Russo, Mariagrazia Saccà, Elisabetta Sala, Francesca Sala, Francesca Santus, Vittoria Sarno, Alessandra Savino, Raffaella Schirò, Giuseppa Scornavacca, Maria Francesca Siracusano, Adelisa Spalla, Gloria Sturaro, Maria Grazia Toma, Ettore Tomagra, Maria Tortorella, Fausta Trentadue, Marina Trevisan, Silvia Tulisso, Roberta Usella, Anna Valente, Mariangela Valera, Edda Vernile, Valeria Vicario, Lucia Vignutelli, Paolo Vinci, Lucia Vizziello, Rosette Zand, Marco Zanette, Graziano Zucchi, Maria Luisa Zuccolo, Eleonora Morabito, Chiara Liz Pandolfini, Chiara Segre’, Rossella Claudia Cannavo’, Melania Maria Cera, Emma Maria Giugnini, Giovanni Giuliano Semprini

Publikováno v: BMJ Paediatrics Open, Vol 7, Iss 1 (2023)

Objective To estimate the prevalence of overweight at 12 months in an Italian birth cohort and to identify factors related to an increased likelihood of being overweight.Methods The Italian NASCITA birth cohort was analysed. Infants were classified a

Externí odkaz: https://doaj.org/article/4c6e00ed22404ddbbf94da42ce7eabd5

mRNA-1273 boost after BNT162b2 vaccination generates comparable SARS-CoV-2-specific functional responses in naïve and COVID-19-recovered individuals

Autor: Roberto Lozano-Rodríguez, José Avendaño-Ortíz, Verónica Terrón, Karla Montalbán-Hernández, José Casalvilla-Dueñas, Marta Bergón-Gutiérrez, Pablo Mata-Martínez, Alejandro Martín-Quirós, Miguel Ángel García-Garrido, Álvaro del Balzo-Castillo, María Peinado, Laura Gómez, Irene Llorente-Fernández, Gema Martín-Miguel, Carmen Herrero-Benito, Lissette López-Morejón, Carmen Vela-Olmo, Carolina Cubillos-Zapata, Eduardo López-Collazo, Carlos del Fresno

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

IntroductionCOVID-19 vaccines based on mRNA have represented a revolution in the biomedical research field. The initial two-dose vaccination schedule generates potent humoral and cellular responses, with a massive protective effect against severe COV

Externí odkaz: https://doaj.org/article/7381bc1db10a43eebad5271b06226978

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