Výsledky vyhledávání - "dehydropyrrolizidine"

Akademický článek

Dehydropyrrolizidine Alkaloid Toxicity, Cytotoxicity, and Carcinogenicity

Autor: Bryan L. Stegelmeier, Steven M. Colegate, Ammon W. Brown

Publikováno v: Toxins, Vol 8, Iss 12, p 356 (2016)

Dehydropyrrolizidine alkaloid (DHPA)-producing plants have a worldwide distribution amongst flowering plants and commonly cause poisoning of livestock, wildlife, and humans. Previous work has produced considerable understanding of DHPA metabolism, to

Externí odkaz: https://doaj.org/article/68bc8dffcc7d43bc9e1169ebd1a68c06

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The Comparative Cytotoxicity of Riddelliine in Primary Mouse, Rat and Chick Hepatocytes

Autor: Stegelmeier, Bryan L., Resager, William S, Colegate, Steven M

Publikováno v: Poisonous Plant Research (PPR)

Dehydropyrrolizidine alkaloid (DHPA) producing plants commonly poison livestock, wildlife and humans. Poisoning occurs when DHPAs are ingested as feed or food, or when they contaminate medicinal or herbal products. Direct toxicologic comparison of in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd2d012710110b04f24e8732871d5c6

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Inhibition of Drp1 protects against senecionine-induced mitochondria-mediated apoptosis in primary hepatocytes and in mice

Autor: Li Yang, Aizhen Xiong, Wen-Xing Ding, Hua Wang, Hong-Min Ni, Xiao Yang, Zhengtao Wang, Hiromi Sesaki

Publikováno v: Redox Biology, Vol 12, Iss, Pp 264-273 (2017)
Redox Biology

Pyrrolizidine alkaloids (PAs) are a group of compounds found in various plants and some of them are widely consumed in the world as herbal medicines and food supplements. PAs are potent hepatotoxins that cause irreversible liver injury in animals and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e9e6428ec7632340316ab8afa41ea60
http://www.sciencedirect.com/science/article/pii/S2213231717300745

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Duration of an induced resistance of sheep to acute poisoning by Crotalaria retusa seeds

Autor: Lisanka A. Maia, Franklin Riet-Correa, Antônio Flávio Medeiros Dantas, Steven M. Colegate, Angélica Fernandes Rodrigues, Clarice R.M. Pessoa, Rosane M.T. Medeiros

Publikováno v: Ciência Rural v.44 n.6 2014
Ciência Rural
Universidade Federal de Santa Maria (UFSM)
instacron:UFSM
Ciência Rural, Vol 44, Iss 6, Pp 1054-1059 (2014)
Ciência Rural, Volume: 44, Issue: 6, Pages: 1054-1059, Published: JUN 2014

The aim of this study was to determine the duration of the resistance after the end of the ingestion of non-toxic doses of Crotalaria retusa seeds. Ten sheep were divided into 3 groups of 3 animals each and a control group with 1 sheep. To induce res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23db13fab776cd357a426a552c19f16f
https://doi.org/10.1590/s0103-84782014000600017

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Profiling of Dehydropyrrolizidine Alkaloids and their N-Oxides in Herbarium-Preserved Specimens of Amsinckia Species Using HPLC-esi(+)MS

Autor: Kip E. Panter, Stanley L. Welsh, Joseph M. Betz, Dale R. Gardner, Steven M. Colegate

Publikováno v: Journal of Agricultural and Food Chemistry

Species of the Amsinckia genus (Boraginaceae) are known to produce potentially hepato-, pneumo-, and/or genotoxic dehydropyrrolizidine alkaloids. However, the taxonomic differentiation of Amsinckia species can be very subtle and there seems to be mar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d23eacc8f4531e008ec24c495735f49b
https://doi.org/10.1021/jf500425v

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Dehydropyrrolizidine Alkaloid Toxicity, Cytotoxicity, and Carcinogenicity

Autor: Ammon W Brown, Bryan L. Stegelmeier, Steven M. Colegate

Publikováno v: Toxins
Toxins, Vol 8, Iss 12, p 356 (2016)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e09f5e398e8940c5b2bda0f83e36f523
http://europepmc.org/articles/PMC5198550

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Relative Toxicity of Select Dehydropyrrolizidine Alkaloids and Evaluation of a Heterozygous P53 Knockout Mouse Model for Dehydropyrrolizidine Alkaloid Induced Carcinogenesis

Autor: Brown, Ammon W.

Publikováno v: All Graduate Theses and Dissertations

Dehydropyrrolizidine alkaloids (DHPAs) are a large group of globally important plant-derived pro-toxins that can contaminate or are naturally present in animal feed and the human food supply as well as herbal supplements. Their bioactive metabolites

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::752c13ce35d355911687199775581bcd
https://digitalcommons.usu.edu/etd/4519

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