HDAC6 Deficiency Has Moderate Effects on Behaviors and Parkinson's Disease Pathology in Mice.

Autor: Zhao, Jiayin¹ (AUTHOR), He, Yongtao¹ (AUTHOR), Duan, Yufei¹ (AUTHOR) 22111520073@m.fudan.edu.cn, Ma, Yuanyuan¹ (AUTHOR), Dong, Hongtian¹ (AUTHOR), Zhang, Xiaoshuang¹ (AUTHOR), Fang, Rong¹ (AUTHOR), Zhang, Yunhe¹ (AUTHOR), Yu, Mei¹ (AUTHOR) yumei@fudan.edu.cn, Huang, Fang¹ (AUTHOR) yumei@fudan.edu.cn

Publikováno v: International Journal of Molecular Sciences. Jun2023, Vol. 24 Issue 12, p9975. 19p.

Changes in Striatal Medium Spiny Neuron Morphology Resulting from Dopamine Depletion are Reversible

Autor: Witzig, Victoria Sofie, Komnig, Daniel, Falkenburger, Björn H.

Publikováno v: Cells, Vol 9, Iss 2441, p 2441 (2020)
Cells
Cells 9(11), 2441-(2020). doi:10.3390/cells9112441
Volume 9
Issue 11
Cells : open access journal 9(11), 2441 (2020). doi:10.3390/cells9112441

The classical motor symptoms of Parkinson&rsquo
s disease (PD) are caused by degeneration of dopaminergic neurons in the substantia nigra, which is followed by secondary dendritic pruning and spine loss at striatal medium spiny neurons (MSN). We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de4ca74a61635d26e0d7f13c9d7ec63c
https://www.mdpi.com/2073-4409/9/11/2441

Olfactory neuron-specific expression of A30P α-synuclein exacerbates dopamine deficiency and hyperactivity in a novel conditional model of early Parkinson's disease stages

Autor: Philipp J. Kahle, Zacharias Kohl, Stephan von Hörsten, Leanie Koch, Thirumalaisamy P. Velavan, Oscar Arias-Carrión, Jana Boy, Carsten Calaminus, Huu P. Nguyen, Markus Fendt, Jacqueline Schneider, Olaf Riess, Rolf Dermietzel, Rejko Krüger, Silke Nuber, Peter Teismann, Elisabeth Petrasch-Parwez, Anna Samarina

Publikováno v: Neurobiology of disease 44(2), 192-204 (2011). doi:10.1016/j.nbd.2011.06.017
Neurobiology of Disease, Vol 44, Iss 2, Pp 192-204 (2011)

Mutations in the N-terminus of the gene encoding α-synuclein (α-syn) are linked to autosomal dominantly inherited Parkinson's disease (PD). The vast majority of PD patients develop neuropsychiatric symptoms preceding motor impairments. During this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53b0bdc057263934165c4b72382eb865

Experimental Zebrafish Models of Mitochondrial Dysfunction in the Pathogenesis of CNS Diseases.

Autor: Yushko, L. V.¹ (AUTHOR), Kotova, M. M.¹ (AUTHOR), Vyunova, T. V.² (AUTHOR), Kalueff, A. V.^1,3,4,5,6 (AUTHOR) avkalueff@gmail.com

Publikováno v: Journal of Evolutionary Biochemistry & Physiology. Nov2023, Vol. 59 Issue 6, p2114-2128. 15p.

Intersecting Pathways: Treating Cocaine Withdrawal and Restless Leg Syndrome with Iron and Buproprion.

Autor: Hughes, Sarah, Hill, Olivia, Mogallapu, Raja

Publikováno v: Healthcare (2227-9032); Aug2024, Vol. 12 Issue 16, p1570, 7p