Zobrazeno 1 - 10
of 114
pro vyhledávání: '"defective viral genomes"'
Autor:
Justin W. Brennan, Yan Sun
Publikováno v:
mBio, Vol 15, Iss 5 (2024)
ABSTRACTDefective viral genomes (DVGs) are truncated derivatives of their parental viral genomes generated during an aberrant round of viral genomic replication. Distinct classes of DVGs have been identified in most families of both positive- and neg
Externí odkaz:
https://doaj.org/article/a38bb0609abb4d209e41a1cf4541fb98
Autor:
Tathiana Ferreira Sa Antunes, José C. Huguet-Tapia, Santiago F. Elena, Svetlana Y. Folimonova
Publikováno v:
Viruses, Vol 16, Iss 9, p 1385 (2024)
Due to the error-prone nature of viral RNA-dependent RNA polymerases, the replication of RNA viruses results in a diversity of viral genomes harboring point mutations, deletions, insertions, and genome rearrangements. Citrus tristeza virus (CTV), a c
Externí odkaz:
https://doaj.org/article/d79a6ba876e24ecbbdfab3e30f51419b
Akademický článek
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Autor:
Terry Zhou, Nora J. Gilliam, Sizhen Li, Simone Spandau, Raven M. Osborn, Sarah Connor, Christopher S. Anderson, Thomas J. Mariani, Juilee Thakar, Stephen Dewhurst, David H. Mathews, Liang Huang, Yan Sun
Publikováno v:
mBio, Vol 14, Iss 3 (2023)
ABSTRACT Defective viral genomes (DVGs) have been identified in many RNA viruses as a major factor influencing antiviral immune response and viral pathogenesis. However, the generation and function of DVGs in SARS-CoV-2 infection are less known. In t
Externí odkaz:
https://doaj.org/article/7157f575c6c3444ca9ca7f50eefeb9f6
Autor:
Jane X. Yeh, Yunfan Fan, Maggie L. Bartlett, Xiaoyan Zhang, Norah Sadowski, Debra A. Hauer, Winston Timp, Diane E. Griffin
Publikováno v:
mBio, Vol 13, Iss 5 (2022)
ABSTRACT Alphaviruses are positive-sense RNA viruses that are important causes of viral encephalomyelitis. Sindbis virus (SINV), the prototype alphavirus, preferentially infects neurons in mice and is a model system for studying mechanisms of viral c
Externí odkaz:
https://doaj.org/article/e66f34ab3fd2479884dde99df6b66f4c
Akademický článek
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Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Dengue virus, a positive-sense single-stranded RNA virus, continuously threatens human health. Although several criteria for evaluation of severe dengue have been recently established, the ability to prognose the risk of severe outcomes for dengue pa
Externí odkaz:
https://doaj.org/article/3631a79b6b444848b9653b01314102fa
Publikováno v:
Viruses, Vol 14, Iss 12, p 2773 (2022)
Defective interfering particles (DIPs) are particles containing defective viral genomes (DVGs) generated during viral replication. DIPs have been found in various RNA viruses, especially in influenza viruses. Evidence indicates that DIPs interfere wi
Externí odkaz:
https://doaj.org/article/e4afc10e9b4f46d1bf48d70bacb9f6c9
Autor:
Maria J. Olmo-Uceda, Juan C. Muñoz-Sánchez, Wilberth Lasso-Giraldo, Vicente Arnau, Wladimiro Díaz-Villanueva, Santiago F. Elena
Publikováno v:
Viruses, Vol 14, Iss 5, p 1114 (2022)
The generation of different types of defective viral genomes (DVG) is an unavoidable consequence of the error-prone replication of RNA viruses. In recent years, a particular class of DVGs, those containing long deletions or genome rearrangements, has
Externí odkaz:
https://doaj.org/article/9e3a95651b2443a1a1a3871e2a58995f
Akademický článek
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