Zobrazeno 1 - 10
of 54
pro vyhledávání: '"defective genomes"'
Publikováno v:
Viruses, Vol 16, Iss 4, p 644 (2024)
Virus-encoded replicases often generate aberrant RNA genomes, known as defective viral genomes (DVGs). When co-infected with a helper virus providing necessary proteins, DVGs can multiply and spread. While DVGs depend on the helper virus for propagat
Externí odkaz:
https://doaj.org/article/330e869fcca948218a48fb2ebcf653c0
Autor:
Amir Ghorbani, John M. Ngunjiri, Gloria Rendon, Christopher B. Brooke, Scott P. Kenney, Chang-Won Lee
Publikováno v:
Viruses, Vol 15, Iss 10, p 2107 (2023)
Influenza A virus (IAV) populations harbor large subpopulations of defective-interfering particles characterized by internally deleted viral genomes. These internally deleted genomes have demonstrated the ability to suppress infectivity and boost inn
Externí odkaz:
https://doaj.org/article/d259cfc757a440fc94edf0b21ef88107
Akademický článek
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Publikováno v:
Retrovirology, Vol 16, Iss 1, Pp 1-5 (2019)
Abstract Antiretroviral therapy (ART) can effectively suppress ongoing HIV replication and block disease progression, but the infection is never cured due to the persistence of a small pool of latently infected cells hosting integrated replication-co
Externí odkaz:
https://doaj.org/article/017b226a9f99482eb6989cad37ab1b27
Akademický článek
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Autor:
Eirini Karamichali, Hajar Chihab, Athanassios Kakkanas, Agnes Marchio, Timokratis Karamitros, Vasiliki Pogka, Agoritsa Varaklioti, Antonis Kalliaropoulos, Beatrice Martinez-Gonzales, Pelagia Foka, Ioannis Koskinas, Andreas Mentis, Soumaya Benjelloun, Pascal Pineau, Urania Georgopoulou
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Defective interfering (DI) RNAs have been detected in several human viruses. HCV in-frame deletions mutants (IFDMs), missing mainly the envelope proteins, have been found in patient sera and liver tissues. IFDMs replicate independently and can be tra
Externí odkaz:
https://doaj.org/article/47876926690842079467ee0150f391e1
Autor:
Natasha L, Tilston-Lunel, Stephen R, Welch, Sham, Nambulli, Rory D, de Vries, Gregory W, Ho, David E, Wentworth, Reed, Shabman, Stuart T, Nichol, Christina F, Spiropoulou, Rik L, de Swart, Linda J, Rennick, W Paul, Duprex
Publikováno v:
mSphere
Defective interfering (DI) genomes restrict viral replication and induce type I interferon. Since DI genomes have been proposed as vaccine adjuvants or therapeutic antiviral agents, it is important to understand their generation, delineate their mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ac2e14fe7335803f8b4198985674614a
https://pubmed.ncbi.nlm.nih.gov/34550005
https://pubmed.ncbi.nlm.nih.gov/34550005
Autor:
Domingo, Esteban
Publikováno v:
Virus as Populations
Genetic variation is a necessity of all biological systems. Viruses use all known mechanisms of variation; mutation, several forms of recombination, and segment reassortment in the case of viruses with a segmented genome. These processes are intimate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_dedup___::42b8266b6d1375b784e09dbf1c63c1b6
http://europepmc.org/articles/PMC7153327
http://europepmc.org/articles/PMC7153327
Autor:
Spaete, Richard R., Frenkel, Niza
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1985 Feb 01. 82(3), 694-698.
Externí odkaz:
https://www.jstor.org/stable/25337
Kniha
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