Zobrazeno 1 - 10
of 2 524
pro vyhledávání: '"dectin-1"'
Autor:
Yuxuan Cai, Ke Wu
Publikováno v:
Current Oncology, Vol 31, Iss 11, Pp 7275-7286 (2024)
Immunotherapy, particularly immune checkpoint inhibitors like PD-1, PD-L1, and CTLA-4, has revolutionized cancer treatment. However, the role of the innate immune system, especially pattern recognition receptors, in cancer development and immunity is
Externí odkaz:
https://doaj.org/article/07ca66ae0ac448a9b3f795bacc1244a7
Autor:
Mónica Cufré, Mercedes Pastorini, Ignacio Martín, Rodrigo Failde, Domingo Palmero, Mercedes Alemán
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-9 (2024)
Abstract Background Dectin-1 is a transmembrane receptor that plays a pivotal role in recognising fungi and Mycobacterium tuberculosis (Mtb). A specific variant, DECTIN-1 rs16910526, results in a truncated receptor that disrupts membrane expression a
Externí odkaz:
https://doaj.org/article/b039a1fdfead429781030e626bc8475c
Autor:
Liu Guibo, Dong Chunxu, Chen Biao, Hu Zhaolei, Liu Wenwen, Ji Xiangnan, Peng Wentao, Chang Hongmin, Li Yonghua, Zhu Guoqiang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
AimThe aim of this study was to investigate whether Dectin-1 influences the immune-inflammatory response in A. fumigatus keratitis by modulating macrophage polarization.Methods1. The models of 1-day, 3-day, and 5-day of fungal keratitis were establis
Externí odkaz:
https://doaj.org/article/27b0078af0074f27a0dad48d94919307
Autor:
Satya Ranjan Sahu, Abinash Dutta, Doureradjou Peroumal, Premlata Kumari, Bhabasha Gyanadeep Utakalaja, Shraddheya Kumar Patel, Narottam Acharya
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 6, Pp 1254-1283 (2024)
Abstract Disseminated fungal infections account for ~1.5 million deaths per year worldwide, and mortality may increase further due to a rise in the number of immunocompromised individuals and drug-resistance fungal species. Since an approved antifung
Externí odkaz:
https://doaj.org/article/b93bc1c0f9664b2b9dc23a43d020d6e8
Autor:
Nilanjan Ganguly, Tapasi Das, Avishek Bhuniya, Ipsita Guha, Mohona Chakravarti, Sukanya Dhar, Anirban Sarkar, Saurav Bera, Jesmita Dhar, Shayani Dasgupta, Akata Saha, Tithi Ghosh, Juhina Das, Ugir Hossain Sk, Saptak Banerjee, Subrata Laskar, Anamika Bose, Rathindranath Baral
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-26 (2024)
Abstract Background A water-soluble ingredient of mature leaves of the tropical mahogany ‘Neem’ (Azadirachta indica), was identified as glycoprotein, thus being named as ‘Neem Leaf Glycoprotein’ (NLGP). This non-toxic leaf-component regressed
Externí odkaz:
https://doaj.org/article/57ec6b66f76846b985ce042d2195c007
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Valéria Lima Kaminski, Bruno Montanari Borges, Bianca Vieira Santos, Nycolas Willian Preite, Vera Lucia Garcia Calich, Flávio Vieira Loures
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
BackgroundParacoccidioidomycosis (PCM) is a systemic endemic fungal disease prevalent in Latin America. Previous studies revealed that host immunity against PCM is tightly regulated by several suppressive mechanisms mediated by tolerogenic plasmacyto
Externí odkaz:
https://doaj.org/article/11d84f92488b4fcf9accbaf4d1190a89
Autor:
Runjin Cai, Xiaoxiao Gong, Xiaozhao Li, Yuanyuan Jiang, Shuanglinzi Deng, Jiale Tang, Huan Ge, Chendong Wu, Huan Tang, Guo Wang, Lei Xie, Xuemei Chen, Xinyue Hu, Juntao Feng
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-19 (2024)
Abstract Background The pattern recognition receptor Dectin-1 was initially discovered to play a pivotal role in mediating pulmonary antifungal immunity and promoting neutrophil-driven inflammation. Recent studies have revealed that Dectin-1 is overe
Externí odkaz:
https://doaj.org/article/e5c539ccbd7b4c0f9210dacfc28c209d