The adipokine sFRP4 induces insulin resistance and lipogenesis in the liver.

Autor: Hörbelt T; Institute of Clinical Biochemistry and Pathobiochemistry, German Diabetes Center at the Heinrich-Heine-University Duesseldorf, Leibniz Center for Diabetes Research, Auf'm Hennekamp 65, 40225 Duesseldorf, Germany; German Center of Diabetes Research Partner, Duesseldorf, Germany; Medical Faculty, Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center (DDZ), Heinrich Heine University, Düsseldorf, Germany., Knebel B; Institute of Clinical Biochemistry and Pathobiochemistry, German Diabetes Center at the Heinrich-Heine-University Duesseldorf, Leibniz Center for Diabetes Research, Auf'm Hennekamp 65, 40225 Duesseldorf, Germany; German Center of Diabetes Research Partner, Duesseldorf, Germany., Fahlbusch P; Institute of Clinical Biochemistry and Pathobiochemistry, German Diabetes Center at the Heinrich-Heine-University Duesseldorf, Leibniz Center for Diabetes Research, Auf'm Hennekamp 65, 40225 Duesseldorf, Germany; German Center of Diabetes Research Partner, Duesseldorf, Germany; Medical Faculty, Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center (DDZ), Heinrich Heine University, Düsseldorf, Germany., Barbosa D; Institute of Clinical Biochemistry and Pathobiochemistry, German Diabetes Center at the Heinrich-Heine-University Duesseldorf, Leibniz Center for Diabetes Research, Auf'm Hennekamp 65, 40225 Duesseldorf, Germany; German Center of Diabetes Research Partner, Duesseldorf, Germany; Medical Faculty, Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center (DDZ), Heinrich Heine University, Düsseldorf, Germany., de Wiza DH; Institute of Clinical Biochemistry and Pathobiochemistry, German Diabetes Center at the Heinrich-Heine-University Duesseldorf, Leibniz Center for Diabetes Research, Auf'm Hennekamp 65, 40225 Duesseldorf, Germany; German Center of Diabetes Research Partner, Duesseldorf, Germany., Van de Velde F; Department of Endocrinology, Ghent University Hospital, Ghent, Belgium., Van Nieuwenhove Y; Department of Gastrointestinal Surgery, Ghent University Hospital, Ghent, Belgium., Lapauw B; Department of Endocrinology, Ghent University Hospital, Ghent, Belgium., Thoresen GH; Section for Pharmacology and Pharmaceutical Biosciences, Department of Pharmacy, University of Oslo, Oslo, Norway; Department of Pharmacology, Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Al-Hasani H; Institute of Clinical Biochemistry and Pathobiochemistry, German Diabetes Center at the Heinrich-Heine-University Duesseldorf, Leibniz Center for Diabetes Research, Auf'm Hennekamp 65, 40225 Duesseldorf, Germany; German Center of Diabetes Research Partner, Duesseldorf, Germany; Medical Faculty, Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center (DDZ), Heinrich Heine University, Düsseldorf, Germany., Müller-Wieland D; Clinical Research Centre, Department of Internal Medicine I, University Hospital Aachen, Aachen, Germany., Ouwens DM; Institute of Clinical Biochemistry and Pathobiochemistry, German Diabetes Center at the Heinrich-Heine-University Duesseldorf, Leibniz Center for Diabetes Research, Auf'm Hennekamp 65, 40225 Duesseldorf, Germany; German Center of Diabetes Research Partner, Duesseldorf, Germany; Department of Endocrinology, Ghent University Hospital, Ghent, Belgium., Kotzka J; Institute of Clinical Biochemistry and Pathobiochemistry, German Diabetes Center at the Heinrich-Heine-University Duesseldorf, Leibniz Center for Diabetes Research, Auf'm Hennekamp 65, 40225 Duesseldorf, Germany; German Center of Diabetes Research Partner, Duesseldorf, Germany. Electronic address: joerg.kotzka@ddz.de.

Publikováno v: Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2019 Oct 01; Vol. 1865 (10), pp. 2671-2684. Date of Electronic Publication: 2019 Jul 20.

Role of secreted frizzled-related protein 4 in prediabetes and type 2 diabetes: a cross sectional study.

Autor: Sánchez-Pozos, Katy¹, Granados-Silvestre, MA¹, Nieto-Velázquez, NG¹, Mejía-Blanquel, María Alicia¹, Galicia-Martínez, Natsyelli¹, Mandujano-Cerón, Jessica¹, Jaimes-Santoyo, Joel¹, Ortiz-López, María Guadalupe¹ gortizl@prodigy.net.mx

Publikováno v: BMC Endocrine Disorders. 6/4/2024, Vol. 24 Issue 1, p1-10. 10p.

Secretory products from epicardial adipose tissue of patients with type 2 diabetes mellitus induce cardiomyocyte dysfunction.

Autor: Greulich S, Maxhera B, Vandenplas G, de Wiza DH, Smiris K, Mueller H, Heinrichs J, Blumensatt M, Cuvelier C, Akhyari P, Ruige JB, Ouwens DM, Eckel J

Publikováno v: Circulation; 11/6/2012, Vol. 126 Issue 19, p2324-2334, 11p

Sirtuin1, not NAMPT, possesses anti-inflammatory effects in epicardial, pericardial and subcutaneous adipose tissue in patients with CHD.

Autor: Opstad, Trine Baur^1,2 (AUTHOR) t.b.opstad@medisin.uio.no, Papotti, Bianca³ (AUTHOR), Åkra, Sissel¹ (AUTHOR), Hansen, Charlotte Holst¹ (AUTHOR), Braathen, Bjørn⁴ (AUTHOR), Tønnessen, Theis^2,4 (AUTHOR), Solheim, Svein¹ (AUTHOR), Seljeflot, Ingebjørg^1,2 (AUTHOR)

Publikováno v: Journal of Translational Medicine. Dec20239/21/2023, Vol. 21 Issue 1, p1-12. 12p.

Cardioprotective properties of omentin-1 in type 2 diabetes: evidence from clinical and in vitro studies.

Autor: Greulich S; Institute of Clinical Biochemistry and Pathobiochemistry, German Diabetes Center, Duesseldorf, Germany., Chen WJ, Maxhera B, Rijzewijk LJ, van der Meer RW, Jonker JT, Mueller H, de Wiza DH, Floerke RR, Smiris K, Lamb HJ, de Roos A, Bax JJ, Romijn JA, Smit JW, Akhyari P, Lichtenberg A, Eckel J, Diamant M, Ouwens DM

Publikováno v: PloS one [PLoS One] 2013; Vol. 8 (3), pp. e59697. Date of Electronic Publication: 2013 Mar 29.