Generating in vitro models of NTRK-fusion mesenchymal neoplasia as tools for investigating kinase oncogenic activation and response to targeted therapy.

Autor: Vanoli F; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Herviou L; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Tsuda Y; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Sung P; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Xie Z; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Fishinevich E; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Min SS; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Mallen W; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., de Wardin HT; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Zhang Y; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Jasin M; Developmental Biology Program, Sloan Kettering Institute, New York, NY, USA., Antonescu CR; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA. antonesc@mskcc.org.

Publikováno v: Oncogenesis [Oncogenesis] 2023 Feb 17; Vol. 12 (1), pp. 8. Date of Electronic Publication: 2023 Feb 17.

FGFR3::TACC3 fusions in head and neck carcinomas: a study of nine cases highlighting phenotypic heterogeneity, frequent HPV association, and a morphologically distinct subset in favor of a putative entity.

Autor: Agaimy A; Institute of Pathology, Erlangen University Hospital, Friedrich Alexander University of Erlangen-Nuremberg, Krankenhausstrasse 8-10, 91054, Erlangen, Germany. abbas.agaimy@uk-erlangen.de.; Comprehensive Cancer Center, European Metropolitan Area Erlangen-Nuremberg (CCC ER-EMN), Friedrich Alexander University of Erlangen-Nuremberg, Erlangen, Germany. abbas.agaimy@uk-erlangen.de., Antonescu CR; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Bell D; Head and Neck/Endocrine Pathology Center of Excellence, Division of Anatomic Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA., Breimer GE; Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands., Dermawan JK; Department of Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH, USA., Kester LA; Department of Head and Neck Surgical Oncology, University Medical Center Utrecht, Utrecht, The Netherlands., Laco J; The Fingerland Department of Pathology, Charles University Faculty of Medicine in Hradec Kralove and University Hospital Hradec Kralove, Hradec Kralove, Czech Republic., Rijken JA; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Whaley RD; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA., Stoehr R; Institute of Pathology, Erlangen University Hospital, Friedrich Alexander University of Erlangen-Nuremberg, Krankenhausstrasse 8-10, 91054, Erlangen, Germany.; Comprehensive Cancer Center, European Metropolitan Area Erlangen-Nuremberg (CCC ER-EMN), Friedrich Alexander University of Erlangen-Nuremberg, Erlangen, Germany., Cramer T; Department of Otorhinolaryngology, Head and Neck Surgery, Bundeswehrkrankenhaus Berlin, Berlin, Germany., Bishop JA; Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX, USA.

Publikováno v: Virchows Archiv : an international journal of pathology [Virchows Arch] 2024 Oct 10. Date of Electronic Publication: 2024 Oct 10.