Tumor-Expressed SPPL3 Supports Innate Antitumor Immune Responses.

Autor: Verkerk T; Department of Immunopathology, Sanquin Research, Amsterdam, The Netherlands.; Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., de Waard AA; Department of Immunopathology, Sanquin Research, Amsterdam, The Netherlands.; Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Koomen SJI; Department of Immunopathology, Sanquin Research, Amsterdam, The Netherlands.; Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Sanders J; Department of Immunopathology, Sanquin Research, Amsterdam, The Netherlands.; Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Jorritsma T; Department of Immunopathology, Sanquin Research, Amsterdam, The Netherlands.; Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Pappot AT; Department of Immunopathology, Sanquin Research, Amsterdam, The Netherlands.; Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Zandhuis ND; Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Department of Hematopoiesis, Sanquin Research, Amsterdam, The Netherlands., Zhang T; Center for Proteomics and Metabolomics, LUMC, Leiden, The Netherlands., Wuhrer M; Center for Proteomics and Metabolomics, LUMC, Leiden, The Netherlands., Hoogendijk AJ; Department of Molecular Hematology, Sanquin Research, Amsterdam, The Netherlands., van Alphen FPJ; Department of Molecular Hematology, Sanquin Research, Amsterdam, The Netherlands., van den Biggelaar M; Department of Molecular Hematology, Sanquin Research, Amsterdam, The Netherlands., Stockinger HSJ; Institute for Hygiene and Applied Immunology, Center of Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Wien, Austria., van Gisbergen KPJM; Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Department of Hematopoiesis, Sanquin Research, Amsterdam, The Netherlands., Spaapen RM; Department of Immunopathology, Sanquin Research, Amsterdam, The Netherlands.; Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., van Ham SM; Department of Immunopathology, Sanquin Research, Amsterdam, The Netherlands.; Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, Netherlands.

Publikováno v: European journal of immunology [Eur J Immunol] 2024 Dec 10, pp. e202451129. Date of Electronic Publication: 2024 Dec 10.

PAKC: A novel panel of HLA class I antigen presentation machinery knockout cells from the same genetic origin.

Autor: de Waard AA; Department of Immunopathology, Sanquin Research, Amsterdam, The Netherlands.; Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Verkerk T; Department of Immunopathology, Sanquin Research, Amsterdam, The Netherlands.; Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Jongsma MLM; Department of Immunopathology, Sanquin Research, Amsterdam, The Netherlands.; Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Oncode Institute and Department of Cell and Chemical Biology, LUMC, Leiden, The Netherlands., Hoefakker K; Department of Immunopathology, Sanquin Research, Amsterdam, The Netherlands.; Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Sethumadhavan S; Institute of Biochemistry, Biocenter, Goethe University Frankfurt, Frankfurt, Germany., Gerke C; Institute of Virology, Medical Center University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Spemann Graduate School of Biology and Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany., Bliss S; Department of Immunopathology, Sanquin Research, Amsterdam, The Netherlands.; Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Kong X; Department of Immunopathology, Sanquin Research, Amsterdam, The Netherlands.; Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Janssen GMC; Center for Proteomics and Metabolomics, LUMC, Leiden, The Netherlands., de Ru AH; Center for Proteomics and Metabolomics, LUMC, Leiden, The Netherlands., Claas FHJ; Department of Immunology, LUMC, Leiden, The Netherlands., Mulder A; Department of Immunology, LUMC, Leiden, The Netherlands., Tampé R; Institute of Biochemistry, Biocenter, Goethe University Frankfurt, Frankfurt, Germany., van Veelen PA; Center for Proteomics and Metabolomics, LUMC, Leiden, The Netherlands., Halenius A; Institute of Virology, Medical Center University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany., Spaapen RM; Department of Immunopathology, Sanquin Research, Amsterdam, The Netherlands.; Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.

Publikováno v: European journal of immunology [Eur J Immunol] 2021 Mar; Vol. 51 (3), pp. 734-737. Date of Electronic Publication: 2021 Feb 01.

The SPPL3-Defined Glycosphingolipid Repertoire Orchestrates HLA Class I-Mediated Immune Responses.

Autor: Jongsma MLM; Department of Immunopathology, Sanquin Research, Amsterdam, the Netherlands; Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands; Cancer Center Amsterdam, Amsterdam, the Netherlands; Oncode Institute and Department of Cell and Chemical Biology, LUMC, Leiden, the Netherlands., de Waard AA; Department of Immunopathology, Sanquin Research, Amsterdam, the Netherlands; Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands; Cancer Center Amsterdam, Amsterdam, the Netherlands., Raaben M; Oncode Institute, Division of Biochemistry, the Netherlands Cancer Institute, Amsterdam, the Netherlands., Zhang T; Center for Proteomics and Metabolics, LUMC, Leiden, the Netherlands., Cabukusta B; Oncode Institute and Department of Cell and Chemical Biology, LUMC, Leiden, the Netherlands., Platzer R; Institut für Hygiene und Angewandte Immunologie, Vienna, Austria., Blomen VA; Oncode Institute, Division of Biochemistry, the Netherlands Cancer Institute, Amsterdam, the Netherlands., Xagara A; Department of Immunopathology, Sanquin Research, Amsterdam, the Netherlands; Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands; Cancer Center Amsterdam, Amsterdam, the Netherlands., Verkerk T; Department of Immunopathology, Sanquin Research, Amsterdam, the Netherlands; Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands; Cancer Center Amsterdam, Amsterdam, the Netherlands., Bliss S; Department of Immunopathology, Sanquin Research, Amsterdam, the Netherlands; Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands; Cancer Center Amsterdam, Amsterdam, the Netherlands., Kong X; Department of Immunopathology, Sanquin Research, Amsterdam, the Netherlands; Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands; Cancer Center Amsterdam, Amsterdam, the Netherlands., Gerke C; Institute of Virology, Medical Center University of Freiburg, Freiburg, Germany; Faculty of Medicine, University of Freiburg, Freiburg, Germany; Spemann Graduate School of Biology and Medicine, University of Freiburg, Freiburg, Germany; Faculty of Biology, University of Freiburg, Freiburg, Germany., Janssen L; Oncode Institute and Department of Cell and Chemical Biology, LUMC, Leiden, the Netherlands., Stickel E; Oncode Institute, Division of Biochemistry, the Netherlands Cancer Institute, Amsterdam, the Netherlands., Holst S; Center for Proteomics and Metabolics, LUMC, Leiden, the Netherlands., Plomp R; Center for Proteomics and Metabolics, LUMC, Leiden, the Netherlands., Mulder A; Department of Immunology, LUMC, Leiden, the Netherlands., Ferrone S; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Claas FHJ; Department of Immunology, LUMC, Leiden, the Netherlands., Heemskerk MHM; Department of Hematology, Leiden University Medical Center, Leiden, the Netherlands., Griffioen M; Department of Hematology, Leiden University Medical Center, Leiden, the Netherlands., Halenius A; Institute of Virology, Medical Center University of Freiburg, Freiburg, Germany; Faculty of Medicine, University of Freiburg, Freiburg, Germany., Overkleeft H; Leiden Institute of Chemistry, Leiden University, Leiden, the Netherlands., Huppa JB; Institut für Hygiene und Angewandte Immunologie, Vienna, Austria., Wuhrer M; Center for Proteomics and Metabolics, LUMC, Leiden, the Netherlands., Brummelkamp TR; Oncode Institute, Division of Biochemistry, the Netherlands Cancer Institute, Amsterdam, the Netherlands; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria; Cancer Genomics Center, Amsterdam, the Netherlands., Neefjes J; Oncode Institute and Department of Cell and Chemical Biology, LUMC, Leiden, the Netherlands., Spaapen RM; Department of Immunopathology, Sanquin Research, Amsterdam, the Netherlands; Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands; Cancer Center Amsterdam, Amsterdam, the Netherlands. Electronic address: r.spaapen@sanquin.nl.

Publikováno v: Immunity [Immunity] 2021 Jan 12; Vol. 54 (1), pp. 132-150.e9. Date of Electronic Publication: 2020 Dec 02.

The Role of Glycosphingolipids in Immune Cell Functions.

Autor: Zhang T; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, Netherlands., de Waard AA; Department of Immunopathology, Sanquin Research, Amsterdam, Netherlands.; Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands., Wuhrer M; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, Netherlands., Spaapen RM; Department of Immunopathology, Sanquin Research, Amsterdam, Netherlands.; Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.

Publikováno v: Frontiers in immunology [Front Immunol] 2019 Jan 29; Vol. 10, pp. 90. Date of Electronic Publication: 2019 Jan 29 (Print Publication: 2019).