Prediction of individual lifetime cardiovascular risk and potential treatment benefit: development and recalibration of the LIFE-CVD2 model to four European risk regions.

Autor: Hageman SHJ; Department of Vascular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., Kaptoge S; Department of Public Health and Primary Care, University of Cambridge, CambridgeUK., de Vries TI; Department of Vascular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., Lu W; Department of Epidemiology and Public Health, University College London, London, UK., Kist JM; Health Campus The Hague, Leiden University Medical Center, The Hague, the Netherlands.; National eHealth Living Lab, Leiden University Medical Center, The Hague, the Netherlands., van Os HJA; Health Campus The Hague, Leiden University Medical Center, The Hague, the Netherlands., Numans ME; Health Campus The Hague, Leiden University Medical Center, The Hague, the Netherlands., Läll K; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Bobak M; Department of Epidemiology and Public Health, University College London, London, UK.; RECETOX, Masaryk University, Brno, Czech Republic., Pikhart H; Department of Epidemiology and Public Health, University College London, London, UK.; RECETOX, Masaryk University, Brno, Czech Republic., Kubinova R; National Institute of Public Health, Prague, Czech Republic., Malyutina S; Independent Researcher., Pająk A; Department of Epidemiology and Population Studies, Institute of Public Health, Faculty of Health Sciences, Jagiellonian University Medical College, Kraków, Poland., Tamosiunas A; Institute of Cardiology, Lithuanian University of Health Sciences, Kaunas, Lithuania., Erbel R; Institute for Medical Informatics, Biometry and Epidemiology, University Hospital Essen, University Duisburg-Essen, Essen, Germany., Stang A; Institute for Medical Informatics, Biometry and Epidemiology, University Hospital Essen, University Duisburg-Essen, Essen, Germany., Schmidt B; Institute for Medical Informatics, Biometry and Epidemiology, University Hospital Essen, University Duisburg-Essen, Essen, Germany., Schramm S; Institute for Medical Informatics, Biometry and Epidemiology, University Hospital Essen, University Duisburg-Essen, Essen, Germany., Bolton TR; British Heart Foundation Data Science Centre, Health Data Research UK, London, UK.; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Spackman S; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, CambridgeUK., Bakker SJL; Department of Internal Medicine, University Medical Centre Groningen, University of Groningen, Groningen, Netherlands., Blaha M; Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Johns Hopkins Hospital, Baltimore, MD, USA., Boer JMA; Centre for Prevention, Lifestyle and Health, National Institute for Public Health and the Environment, Bilthoven, The Netherlands., Bonnefond A; Inserm/CNRS UMR 1283/8199, Pasteur Institute of Lille, EGID, Lille, France.; University of Lille, Lille, France; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK., Brenner H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany.; Network Aging Research, University of Heidelberg, Heidelberg, Germany., Brunner EJ; Department of Epidemiology and Public Health, University College London, London, UK., Cook NR; Brigham & Women's Hospital, Harvard Medical School Harvard University, Boston, MA, USA., Davidson K; Feinstein Institutes for Medical Research, Northwell Health, New York, NY, USA., Dennison E; MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK., Donfrancesco C; Department of Cardiovascular, Endocrine-Metabolic Diseases and Aging, Istituto Superiore di Sanita', Rome, Italy., Dörr M; Institute for Community Medicine, University Medicine Greifswald, University of Greifswald, Greifswald, Germany.; German Centre for Cardiovascular Disease (DZHK), Partner Site Greifswald.; German Centre for Cardiovascular Disease (DZD), Site Greifswald, Greifswald, Germany., Floyd JS; Cardiovascular Health Research Unit, Departments of Medicine and Epidemiology, University of Washington, Seattle, WA, USA., Ford I; Robertson Center for Biostatistics, University of Glasgow, Glasgow, UK., Fu M; Department of Medicine, Sahlgrenska University Hospital/Östra Hospital, Gothenburg, Sweden., Gansevoort RT; Department of Internal Medicine, University Medical Centre Groningen, University of Groningen, Groningen, Netherlands., Giampaoli S; former Istituto Superiore di Sanità, Rome, Italy., Gillum RF; Howard University Hospital, Washington, DC, USA., Gómez-de-la-Cámara A; Instituto de Investigación Hospital 12 de Octubre, Madrid, Spain., Håheim LL; Institute of Oral Biology, Faculty of Dentistry, University of Oslo, Oslo, Norway., Hansson PO; Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, Sahlgrenska Academy, Gothenburg, Sweden., Harms P; Department of General Practice, Amsterdam University Medical Center, Amsterdam, Netherlands., Humphries SE; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, UK., Ikram MK; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands., Jukema JW; Department of Cardiology, Leiden University Medical Center, The Netherlands.; Netherlands Heart Institute, Leiden, the Netherlands., Kavousi M; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands., Kiechl S; Department of Neurology, Innsbruck Medical University and VASCage, Research Centre on Vascular Ageing and Stroke, Innsbruck, Austria., Kucharska-Newton A; College of Public Health, Department of Epidemiology, University of Kentucky, KY, USA., Pablos DL; Instituto de Investigación Hospital 12 de Octubre, Universidad Complutense de Madrid (UCM), Madrid, Spain., Matsushita K; Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA., Meyer HE; Norwegian Institute of Public Health, Oslo, Norway., Moons KGM; Julius Center for Health Sciences and Primary Care, UMC Utrecht, Utrecht University, Utrecht, The Netherlands., Mortensen MB; Department of Clinical Biochemistry, Copenhagen University Hospital - Herlev Gentofte, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Muilwijk M; Department of Epidemiology and Data Science, Amsterdam University Medical Center, Amsterdam, Netherlands., Nordestgaard BG; Department of Clinical Biochemistry, Copenhagen University Hospital - Herlev Gentofte, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Packard C; School of Cardiovascular & Metabolic Health, University of Glasgow, Glasgow, UK., Pamieri L; Department of Cardiovascular, Dysmetabolic and Aging-associated Diseases, Istituto Superiore di Sanità, Rome, Italy., Panagiotakos D; Harokopio University, Athens, Greece., Peters A; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; IBE, Pettenkofer School of Public Health, Medical Faculty, Ludwig-Maximilians-Universität, Munich, Germany.; German Centre for Cardiovascular Research (DZHK e.V.), partner site Munich Heart Alliance, Munich, Germany., Potier L; Université Paris City, Paris, France.; Department of Diabetology, Endocrinology and Nutrition, Assistance Publique - Hôpitaux de Paris, Bichat Hospital, Paris, France., Providencia R; Institute of Health Informatics Research, University College London, London, UK., Psaty BM; Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA., Ridker PM; Brigham & Women's Hospital, Harvard Medical School Harvard University, Boston, MA, USA., Rodriguez B; University of Hawaii and Tecnologico de Monterrey, Honolulu, HI, USA., Rosengren A; Sahlgrenska University Hospital and Östra Hospital, Göteborg, Sweden., Sattar N; School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK., Schöttker B; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany.; Network Aging Research, University of Heidelberg, Heidelberg, Germany., Schwartz JE; Columbia University, New York, NY, USA., Shea S; College of Physicians & Surgeons and Mailman School of Public Health, Columbia University, NY, USA., Shipley MJ; Department of Epidemiology and Public Health, University College London, London, UK., Sofat R; Department of Pharmacology and Therapeutics, University of Liverpool, Liverpool, UK., Thorand B; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; IBE, Pettenkofer School of Public Health, Medical Faculty, Ludwig-Maximilians-Universität, Munich, Germany., Verschuren WMM; Centre for Prevention, Lifestyle and Health, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.; Julius Center for Health Sciences and Primary Care, UMC Utrecht, Utrecht University, Utrecht, The Netherlands., Völzke H; Institute for Community Medicine, University Medicine Greifswald, University of Greifswald, Greifswald, Germany.; German Centre for Cardiovascular Disease (DZHK), Partner Site Greifswald.; German Centre for Cardiovascular Disease (DZD), Site Greifswald, Greifswald, Germany., Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, University of Cambridge, Cambridge, UK., Westbury L; MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK., Willeit P; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Department of Medical Statistics, Informatics and Health Economics, Medical University of Innsbruck, Innsbruck, Austria., Zhou B; Faculty of Medicine, School of Public Health, Imperial College London, London, UK., Danesh J; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, CambridgeUK., Visseren FLJ; Department of Vascular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., Di Angelantonio E; Department of Public Health and Primary Care, University of Cambridge, CambridgeUK., Pennells L; Department of Public Health and Primary Care, University of Cambridge, CambridgeUK., Dorresteijn JAN; Department of Vascular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.

Publikováno v: European journal of preventive cardiology [Eur J Prev Cardiol] 2024 Oct 10; Vol. 31 (14), pp. 1690-1699.

Impact of a Patient's Baseline Risk on the Relative Benefit and Harm of a Preventive Treatment Strategy: Applying Trial Results in Clinical Decision Making.

Autor: de Vries TI; Department of Vascular Medicine University Medical Center Utrecht Utrecht the Netherlands., Stam-Slob MC; Department of Vascular Medicine University Medical Center Utrecht Utrecht the Netherlands., Peters RJG; Department of Cardiology Amsterdam University Medical CenterAcademic Medical Center/University of Amsterdam Amsterdam the Netherlands., van der Graaf Y; Julius Center for Health Sciences and Primary Care Utrecht the Netherlands., Westerink J; Department of Vascular Medicine University Medical Center Utrecht Utrecht the Netherlands., Visseren FLJ; Department of Vascular Medicine University Medical Center Utrecht Utrecht the Netherlands.

Publikováno v: Journal of the American Heart Association [J Am Heart Assoc] 2022 Jan 04; Vol. 11 (1), pp. e017605. Date of Electronic Publication: 2021 Dec 22.

Cardiovascular risk prediction tools made relevant for GPs and patients.

Autor: de Vries TI; Department of Vascular Medicine, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands., Visseren FLJ; Department of Vascular Medicine, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands F.L.J.Visseren@umcutrecht.nl.

Publikováno v: Heart (British Cardiac Society) [Heart] 2020 Oct 19. Date of Electronic Publication: 2020 Oct 19.

Estimating individual lifetime benefit and bleeding risk of adding rivaroxaban to aspirin for patients with stable cardiovascular disease: results from the COMPASS trial.

Autor: de Vries TI; Department of Vascular Medicine, University Medical Center Utrecht, University Utrecht, GA Utrecht, The Netherlands., Eikelboom JW; Population Health Research Institute, McMaster University and Hamilton Health Sciences, 237 Barton Street East, Hamilton, ON, Canada., Bosch J; Population Health Research Institute, McMaster University and Hamilton Health Sciences, 237 Barton Street East, Hamilton, ON, Canada., Westerink J; Department of Vascular Medicine, University Medical Center Utrecht, University Utrecht, GA Utrecht, The Netherlands., Dorresteijn JAN; Department of Vascular Medicine, University Medical Center Utrecht, University Utrecht, GA Utrecht, The Netherlands., Alings M; Department of Cardiology, Amphia Hospital, Langendijk 75, EV Breda, The Netherlands., Dyal L; Population Health Research Institute, McMaster University and Hamilton Health Sciences, 237 Barton Street East, Hamilton, ON, Canada., Berkowitz SD; Clinical Development, Thrombosis, Bayer U.S. LLC, Whippany, NJ, USA., van der Graaf Y; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, University Utrecht, Universiteitsweg 100, CG Utrecht, The Netherlands., Fox KAA; Centre for Cardiovascular Science, University of Edinburgh, 49 Little France Crescent, Edinburgh, UK., Visseren FLJ; Department of Vascular Medicine, University Medical Center Utrecht, University Utrecht, GA Utrecht, The Netherlands.

Publikováno v: European heart journal [Eur Heart J] 2019 Dec 07; Vol. 40 (46), pp. 3771-3778a.

Heterogeneity of Treatment Effects From an Intensive Lifestyle Weight Loss Intervention on Cardiovascular Events in Patients With Type 2 Diabetes: Data From the Look AHEAD Trial.

Autor: de Vries TI; Department of Vascular Medicine, University Medical Center Utrecht, Utrecht, the Netherlands., Dorresteijn JAN; Department of Vascular Medicine, University Medical Center Utrecht, Utrecht, the Netherlands., van der Graaf Y; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands., Visseren FLJ; Department of Vascular Medicine, University Medical Center Utrecht, Utrecht, the Netherlands., Westerink J; Department of Vascular Medicine, University Medical Center Utrecht, Utrecht, the Netherlands j.westerink-3@umcutrecht.nl.

Publikováno v: Diabetes care [Diabetes Care] 2019 Oct; Vol. 42 (10), pp. 1988-1994. Date of Electronic Publication: 2019 Aug 15.