Zobrazeno 1 - 10
of 30
pro vyhledávání: '"de Vries Le"'
Autor:
Julie M. J. Verhoef, Rosemary Rochford, Philip J. Rosenthal, Graham P. Trevitt, Patrick K Tumwebaze, Barcelo C, Manuel Llinás, Jacquin C. Niles, Koen J. Dechering, Henderson R, Roger Bonnert, Dhelio Batista Pereira, Anna Caroline Campos Aguiar, Huijs T, Judith M. Bolscher, David A. Fidock, Tomas Yeo, Robert W. Sauerwein, Pasaje Cfa, Jake Baum, Patrick A. M. Jansen, Brice Campo, Roland A. Cooper, Taco W. A. Kooij, de Vries Le, María Belén Jiménez-Díaz, Iñigo Angulo-Barturen, Francisco J. Gamo, Josefine Striepen, Pedro H. H. Hermkens, Sergio Wittlin, Rafael Victorio Carvalho Guido, Kelly Rubiano, Justin Munro, Fernandez Bc, Laura M. Sanz, Karin M. J. Koolen, J. Schalkwijk, Alisje Churchyard
Drug resistance and a dire lack of transmission-blocking antimalarials hamper malaria elimination. Here, we present the pantothenamide MMV693183 as a first-in-class acetyl-CoA synthetase (ACS) inhibitor to enter preclinical development. Our studies d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::defffb247aaafa1d1e8ba557aa91a1d8
https://doi.org/10.1101/2021.05.12.443866
https://doi.org/10.1101/2021.05.12.443866
Akademický článek
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Publikováno v:
In Value in Health 2002 5(6):590-590
Publikováno v:
In Value in Health 2002 5(6):589-589
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
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Autor:
Darif ND; European Molecular Biology Laboratory, Heidelberg, Germany., Ganter M; Heidelberg University, Heidelberg, Germany., Dziekan JM; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia., Kilian N; Department of Biological Sciences, California State University, Chico, CA, USA; Department of Medical Biochemistry, Faculty of Basic Medical Sciences, Delta State University, Abraka, Nigeria., Brancucci N; Swiss Tropical and Public Health Institute, University of Basel, Basel, Switzerland., Ng C; University of Nebraska Medical Center, Omaha, NE, USA., de Vries LE; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Guttery D; University of Leicester, Leicester, UK., Philip N; University of Edinburgh, Edinburgh, UK., Boddey JA; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia., Metwally NG; Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany., Okumu F; Ifakara Health Institute, Ifakara, Tanzania; School of Biodiversity, One Health and Veterinary Medicine, University of Glasgow, Glasgow, UK. Electronic address: fredros@ihi.or.tz., Kooij TWA; Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands. Electronic address: Taco.Kooij@radboudumc.nl., Absalon S; Department of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, IN, USA. Electronic address: sabsalon@iu.edu., Bryant JM; Institut Pasteur, Université Paris Cité, INSERM U1201, CNRS EMR9195, Biology of Host-Parasite Interactions Unit, F-75015 Paris, France. Electronic address: jessica.bryant@pasteur.fr.
Publikováno v:
Trends in parasitology [Trends Parasitol] 2024 Aug; Vol. 40 (8), pp. 651-656. Date of Electronic Publication: 2024 Jul 15.
Autor:
de Vries LE; Department of Neuroregeneration, Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Meibergdreef 47, 1105 BA, Amsterdam, The Netherlands. l.de.vries@nin.knaw.nl., Jongejan A; Amsterdam UMC Location University of Amsterdam, Epidemiology and Data Science, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.; Amsterdam Public Health, Methodology, Amsterdam, The Netherlands.; Amsterdam Infection and Immunity, Inflammatory Diseases, Amsterdam, The Netherlands., Monteiro Fortes J; Department of Neuropsychiatric Disorders, Netherlands Institute for Neuroscience, Institute of the Royal Netherlands Academy of Arts and Sciences, Meibergdreef 47, 1105 BA, Amsterdam, The Netherlands., Balesar R; Department of Neuropsychiatric Disorders, Netherlands Institute for Neuroscience, Institute of the Royal Netherlands Academy of Arts and Sciences, Meibergdreef 47, 1105 BA, Amsterdam, The Netherlands., Rozemuller AJM; Department of Pathology, Amsterdam Neuroscience, Amsterdam UMC - Location VUmc, Amsterdam, The Netherlands., Moerland PD; Amsterdam UMC Location University of Amsterdam, Epidemiology and Data Science, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.; Amsterdam Public Health, Methodology, Amsterdam, The Netherlands.; Amsterdam Infection and Immunity, Inflammatory Diseases, Amsterdam, The Netherlands., Huitinga I; Department of Neuroimmunology, Netherlands Institute for Neuroscience, Institute of the Royal Netherlands Academy of Arts and Sciences, Meibergdreef 47, 1105 BA, Amsterdam, The Netherlands.; Center for Neuroscience, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, The Netherlands., Swaab DF; Department of Neuropsychiatric Disorders, Netherlands Institute for Neuroscience, Institute of the Royal Netherlands Academy of Arts and Sciences, Meibergdreef 47, 1105 BA, Amsterdam, The Netherlands., Verhaagen J; Department of Neuroregeneration, Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Meibergdreef 47, 1105 BA, Amsterdam, The Netherlands. j.verhaagen@nin.knaw.nl.; Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University, Boelelaan 1085, 1081 HV, Amsterdam, The Netherlands. j.verhaagen@nin.knaw.nl.
Publikováno v:
Acta neuropathologica communications [Acta Neuropathol Commun] 2024 Apr 25; Vol. 12 (1), pp. 68. Date of Electronic Publication: 2024 Apr 25.
Autor:
de Vries LE; Department of Neuroregeneration, Netherlands Institute for Neuroscience, Institute of the Royal Netherlands Academy of Arts and Sciences, 1105 BA, Amsterdam, The Netherlands. l.de.vries@nin.knaw.nl., Huitinga I; Department of Neuroimmunology, Netherlands Institute for Neuroscience, Institute of the Royal Netherlands Academy of Arts and Sciences, 1105 BA, Amsterdam, The Netherlands., Kessels HW; Swammerdam Institute for Life Sciences, Amsterdam Neuroscience, University of Amsterdam, 1098 XH, Amsterdam, the Netherlands., Swaab DF; Department of Neuropsychiatric Disorders, Netherlands Institute for Neuroscience, an Institute of the Royal Netherlands Academy of Arts and Sciences, 1105 BA, Amsterdam, Netherlands., Verhaagen J; Department of Neuroregeneration, Netherlands Institute for Neuroscience, Institute of the Royal Netherlands Academy of Arts and Sciences, 1105 BA, Amsterdam, The Netherlands.; Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University, Boelelaan 1085, 1081 HV, Amsterdam, The Netherlands.
Publikováno v:
Molecular neurodegeneration [Mol Neurodegener] 2024 Apr 08; Vol. 19 (1), pp. 33. Date of Electronic Publication: 2024 Apr 08.
Autor:
de Vries LE; Department of Medical Microbiology, Radboudumc Center for Infectious Diseases, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Jansen PAM; Department of Dermatology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands., Barcelo C; Medicines for Malaria Venture, Geneva, Switzerland., Munro J; Department of Chemistry and Huck Center for Malaria Research, The Pennsylvania State University, University Park, PA, USA., Verhoef JMJ; Department of Medical Microbiology, Radboudumc Center for Infectious Diseases, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands., Pasaje CFA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Rubiano K; Department of Microbiology & Immunology, Columbia University Irving Medical Center, New York, NY, USA., Striepen J; Department of Microbiology & Immunology, Columbia University Irving Medical Center, New York, NY, USA., Abla N; Medicines for Malaria Venture, Geneva, Switzerland., Berning L; TropIQ Health Sciences, Nijmegen, The Netherlands., Bolscher JM; TropIQ Health Sciences, Nijmegen, The Netherlands., Demarta-Gatsi C; Medicines for Malaria Venture, Geneva, Switzerland., Henderson RWM; TropIQ Health Sciences, Nijmegen, The Netherlands., Huijs T; TropIQ Health Sciences, Nijmegen, The Netherlands., Koolen KMJ; TropIQ Health Sciences, Nijmegen, The Netherlands., Tumwebaze PK; Infectious Diseases Research Collaboration, Kampala, Uganda., Yeo T; Department of Microbiology & Immunology, Columbia University Irving Medical Center, New York, NY, USA., Aguiar ACC; Sao Carlos Institute of Physics, University of São Paulo, São Carlos, São Paulo, Brazil, São Carlos, SP, Brazil., Angulo-Barturen I; The Art of Discovery, Derio, Spain., Churchyard A; Department of Life Sciences, Imperial College London, South Kensington, London, United Kingdom., Baum J; Department of Life Sciences, Imperial College London, South Kensington, London, United Kingdom., Fernández BC; Global Health, GlaxoSmithKline, Tres Cantos, Madrid, Spain., Fuchs A; Medicines for Malaria Venture, Geneva, Switzerland., Gamo FJ; Global Health, GlaxoSmithKline, Tres Cantos, Madrid, Spain., Guido RVC; Sao Carlos Institute of Physics, University of São Paulo, São Carlos, São Paulo, Brazil, São Carlos, SP, Brazil., Jiménez-Diaz MB; The Art of Discovery, Derio, Spain., Pereira DB; Research Center for Tropical Medicine of Rondonia, Porto Velho, Brazil., Rochford R; Department of Immunology and Microbiology, University of Colorado Anschutz School of Medicine, Aurora, CO, USA., Roesch C; Malaria Molecular Epidemiology Unit, Institut Pasteur du Cambodge, Phnom Penh, Cambodia.; Malaria Translational Research Unit, Institut Pasteur, Paris & Institut Pasteur du Cambodge, Phnom Penh, Cambodia., Sanz LM; Global Health, GlaxoSmithKline, Tres Cantos, Madrid, Spain., Trevitt G; Sygnature Discovery, Nottingham, United Kingdom., Witkowski B; Malaria Molecular Epidemiology Unit, Institut Pasteur du Cambodge, Phnom Penh, Cambodia.; Malaria Translational Research Unit, Institut Pasteur, Paris & Institut Pasteur du Cambodge, Phnom Penh, Cambodia., Wittlin S; Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland., Cooper RA; Department of Natural Sciences and Mathematics, Dominican University of California, San Rafael, CA, USA., Rosenthal PJ; Department of Medicine, University of California, San Francisco, CA, USA., Sauerwein RW; Department of Medical Microbiology, Radboudumc Center for Infectious Diseases, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.; TropIQ Health Sciences, Nijmegen, The Netherlands., Schalkwijk J; Department of Dermatology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands., Hermkens PHH; Hermkens Pharma Consultancy, Oss, The Netherlands., Bonnert RV; Medicines for Malaria Venture, Geneva, Switzerland., Campo B; Medicines for Malaria Venture, Geneva, Switzerland., Fidock DA; Department of Microbiology & Immunology, Columbia University Irving Medical Center, New York, NY, USA.; Center for Malaria Therapeutics and Antimicrobial Resistance, Division of Infectious Diseases, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA., Llinás M; Department of Chemistry and Huck Center for Malaria Research, The Pennsylvania State University, University Park, PA, USA.; Department of Biochemistry & Molecular Biology, The Pennsylvania State University, University Park, PA, USA., Niles JC; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Kooij TWA; Department of Medical Microbiology, Radboudumc Center for Infectious Diseases, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands. taco.kooij@radboudumc.nl., Dechering KJ; TropIQ Health Sciences, Nijmegen, The Netherlands. k.dechering@tropiq.nl.
Publikováno v:
Nature communications [Nat Commun] 2022 Apr 20; Vol. 13 (1), pp. 2158. Date of Electronic Publication: 2022 Apr 20.