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Integrin alpha9 emerges as a key therapeutic target to reduce metastasis in rhabdomyosarcoma and neuroblastoma.

Autor: Navarro, Natalia, Molist, Carla, Sansa-Girona, Júlia, Zarzosa, Patricia, Gallo-Oller, Gabriel, Pons, Guillem, Magdaleno, Ainara, Guillén, Gabriela, Hladun, Raquel, Garrido, Marta, Segura, Miguel F., Hontecillas-Prieto, Lourdes, de Álava, Enrique, Ponsati, Berta, Fernández-Carneado, Jimena, Almazán-Moga, Ana, Vallès-Miret, Mariona, Farrera-Sinfreu, Josep, de Toledo, Josep Sánchez, Moreno, Lucas

Publikováno v: Cellular & Molecular Life Sciences; Nov2022, Vol. 79 Issue 11, p1-16, 16p

Functional high-throughput screening reveals miR-323a-5p and miR-342-5p as new tumor-suppressive microRNA for neuroblastoma

Autor: Soriano, Aroa, Masanas, Marc, Boloix, Ariadna, Masiá, Núria, París-Coderch, Laia, Piskareva, Olga, Jiménez, Carlos, Henrich, Kai-Oliver, Roma, Josep, Westermann, Frank, Stallings, Raymond L., Sábado, Constantino, de Toledo, Josep Sánchez, Santamaria, Anna, Gallego, Soledad, Segura, Miguel F., Universitat Autònoma de Barcelona, Hospital Universitari Vall d'Hebron

Publikováno v: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Cellular and Molecular Life Sciences
Digital.CSIC. Repositorio Institucional del CSIC
instname

Current therapies for most non-infectious diseases are directed at or affect functionality of the human translated genome, barely 2% of all genetic information. By contrast, the therapeutic potential of targeting the transcriptome, ~ 70% of the genom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::462c75c0ae55f7ed615d0c1990bdbfe2
https://ddd.uab.cat/record/226350

MicroRNA-497 impairs the growth of chemoresistant neuroblastoma cells by targeting cell cycle, survival and vascular permeability genes

Autor: Soriano, Aroa, París-Coderch, Laia, Jubierre Zapater, Luz, Martínez, Alba, Zhou, Xiangyu, Piskareva, Olga, Bray, Isabella, Vidal, Isaac, Almazán-Moga, Anna, Molist, Carla, Roma, Josep, Bayascas Ramírez, José Ramón., Casanovas, Oriol, Stallings, Raymond L., de Toledo, Josep Sánchez, Gallego, Soledad, Segura, Miguel F., Universitat Autònoma de Barcelona. Vall d'Hebron Institut de Recerca (VHIR)

Publikováno v: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Oncotarget

Despite multimodal therapies, a high percentage of high-risk neuroblastoma (NB) become refractory to current treatments, most of which interfere with cell cycle and DNA synthesis or function, activating the DNA damage response (DDR). In cancer, this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::865fb8bb1f70d540662d87872c43b9d2
https://ddd.uab.cat/record/185779

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