Zobrazeno 1 - 5
of 5
pro vyhledávání: '"de Tfa Tom Greef"'
Autor:
Sergey Semenov, de Tfa Tom Greef, van Hwh Rik Roekel, Joost Groen, van der R M Made, Sgj Postma, Wilhelm T. S. Huck, Albert S. Y. Wong
Publikováno v:
Nature Chemistry, 7, 2, pp. 160-165
Nature Chemistry, 7, 160-165
Nature Chemistry, 7(2), 160-165. Nature Publishing Group
Nature Chemistry, 7, 160-165
Nature Chemistry, 7(2), 160-165. Nature Publishing Group
Life is sustained by complex systems operating far from equilibrium and consisting of a multitude of enzymatic reaction networks. The operating principles of biology's regulatory networks are known, but the in vitro assembly of out-of-equilibrium enz
Autor:
S.F. Teunissen, van de E Steeg, Els Wagenaar, Jan H.M. Schellens, A.H. Schinkel, Maj Vlaming, de Tfa Tom Greef, Jos H. Beijnen, Luc Brunsveld, Hilde Rosing, van A Esch
Publikováno v:
Molecular Pharmacology, 85(3), 520-530
Molecular Pharmacology, 3, 85, 520-530
Molecular Pharmacology, 3, 85, 520-530
The multidrug transporters breast cancer resistance protein (BCRP), multidrug-resistance protein 1 (MDR1), and multidrug-resistance-associated protein (MRP) 2 and 3 eliminate toxic compounds from tissues and the body and affect the pharmacokinetics o
Autor:
Luc Brunsveld, S.F. Teunissen, Hilde Rosing, J. H. M. Schellens, de Tfa Tom Greef, Jos H. Beijnen, A.H. Schinkel, Selvi Durmus
Publikováno v:
Chromatographia, 74(3-4), 215-226. Springer
2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is an abundantly present heterocyclic aromatic amine which is found to be carcinogenic in rodents, mice and rats. The biotransformation of PhIP is extensive and involves both the formation of bio
Autor:
Ara Anja Palmans, Robert Graf, Martin Wegner, Dmytro Dudenko, Daniel Sebastiani, de Tfa Tom Greef, Hans-Wolfgang Spiess
Publikováno v:
Chemical Science, 2(10), 2040-2049. Royal Society of Chemistry
Solid-state NMR experiments as well as extensive Car–Parrinello Molecular Dynamics simulations are used to study the dependence of supramolecular self-organization of benzene-1,3,5-tricarboxamides (BTA) on the local orientation of the amide functio
Publikováno v:
Angewandte Chemie. International Edition, 53, 31, pp. 8066-8069
Angewandte Chemie. International Edition, 53, 8066-8069
Angewandte Chemie-International Edition, 53(31), 8806-8069. Wiley
Angewandte Chemie. International Edition, 53, 8066-8069
Angewandte Chemie-International Edition, 53(31), 8806-8069. Wiley
A wet stamping method to precisely control concentrations of enzymes and inhibitors in place and time inside layered gels is reported. By combining enzymatic reactions such as autocatalysis and inhibition with spatial delivery of components through s