Severe COVID-19 Shares a Common Neutrophil Activation Signature with Other Acute Inflammatory States.

Autor: Schimke LF; Department of Imunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508-000, Brazil., Marques AHC; Department of Imunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508-000, Brazil., Baiocchi GC; Department of Imunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508-000, Brazil., de Souza Prado CA; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, São Paulo 05508-000, Brazil., Fonseca DLM; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, São Paulo 05508-000, Brazil., Freire PP; Department of Imunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508-000, Brazil., Rodrigues Plaça D; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, São Paulo 05508-000, Brazil., Salerno Filgueiras I; Department of Imunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508-000, Brazil., Coelho Salgado R; Department of Imunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508-000, Brazil., Jansen-Marques G; Information Systems, School of Arts, Sciences and Humanities, University of Sao Paulo, São Paulo 03828-000, Brazil., Rocha Oliveira AE; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, São Paulo 05508-000, Brazil., Peron JPS; Department of Imunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508-000, Brazil., Cabral-Miranda G; Department of Imunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508-000, Brazil., Barbuto JAM; Department of Imunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508-000, Brazil.; Laboratory of Medical Investigation in Pathogenesis, Targeted Therapy in Onco-Immuno-Hematology (LIM-31), Department of Hematology, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo 05403-000, Brazil., Camara NOS; Department of Imunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508-000, Brazil., Calich VLG; Department of Imunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508-000, Brazil., Ochs HD; Department of Pediatrics, Seattle Children's Research Institute, University of Washington School of Medicine, Seattle, WA 98101, USA., Condino-Neto A; Department of Imunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508-000, Brazil., Overmyer KA; National Center for Quantitative Biology of Complex Systems, Madison, WI 53562, USA.; Morgridge Institute for Research, Madison, WI 53562, USA., Coon JJ; National Center for Quantitative Biology of Complex Systems, Madison, WI 53562, USA.; Morgridge Institute for Research, Madison, WI 53562, USA.; Department of Biomolecular Chemistry, University of Wisconsin, Madison, WI 53506, USA.; Department of Chemistry, University of Wisconsin, Madison, WI 53506, USA., Balnis J; Division of Pulmonary and Critical Care Medicine, Albany Medical Center, Albany, NY 12208, USA.; Department of Molecular and Cellular Physiology, Albany Medical College, Albany, NY 12208, USA., Jaitovich A; Division of Pulmonary and Critical Care Medicine, Albany Medical Center, Albany, NY 12208, USA.; Department of Molecular and Cellular Physiology, Albany Medical College, Albany, NY 12208, USA., Schulte-Schrepping J; Life and Medical Sciences (LIMES) Institute, University of Bonn, 53115 Bonn, Germany.; Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), University of Bonn, 53127 Bonn, Germany., Ulas T; Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), University of Bonn, 53127 Bonn, Germany.; German Center for Neurodegenerative Diseases (DZNE), PRECISE Platform for Genomics and Epigenomics at DZNE, University of Bonn, 53127 Bonn, Germany., Schultze JL; Life and Medical Sciences (LIMES) Institute, University of Bonn, 53115 Bonn, Germany.; Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), University of Bonn, 53127 Bonn, Germany.; German Center for Neurodegenerative Diseases (DZNE), PRECISE Platform for Genomics and Epigenomics at DZNE, University of Bonn, 53127 Bonn, Germany., Nakaya HI; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, São Paulo 05508-000, Brazil.; Hospital Israelita Albert Einstein, São Paulo 05652-900, Brazil.; Scientific Platform Pasteur, University of São Paulo, São Paulo 05508-020, Brazil., Jurisica I; Osteoarthritis Research Program, Division of Orthopedic Surgery, Schroeder Arthritis Institute and Data Science Discovery Centre for Chronic Diseases, Krembil Research Institute, University Health Network, Toronto, ON M5T 0S8, Canada.; Departments of Medical Biophysics and Computer Science, Faculty of Dentistry, University of Toronto, Toronto, ON M5G 1L7, Canada.; Institute of Neuroimmunology, Slovak Academy of Sciences, 845 10 Bratislava, Slovakia., Cabral-Marques O; Department of Imunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508-000, Brazil.; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, São Paulo 05508-000, Brazil.; Network of Immunity in Infection, Malignancy, Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), São Paulo 05508-000, Brazil.

Publikováno v: Cells [Cells] 2022 Mar 01; Vol. 11 (5). Date of Electronic Publication: 2022 Mar 01.