The harmful acute effects of clomipramine in the rat liver: Impairments in mitochondrial bioenergetics

Autor: Bizerra, Paulo Francisco Veiga, Itou da Silva, Fernanda Sayuri, Gilglioni, Eduardo Hideo, Nanami, Letícia Fernanda, Klosowski, Eduardo Makiyama, de Souza, Byanca Thais Lima, Raimundo, Ana Flávia Gatto, dos Santos, Karina Borba Paulino, Mewes, Juliana Moraes, Constantin, Renato Polimeni, Mito, Márcio Shigueaki, Ishii-Iwamoto, Emy Luiza, Constantin, Jorgete, Mingatto, Fábio Ermínio, Esquissato, Giovana Natiele Machado, Marchiosi, Rogério, dos Santos, Wanderley Dantas, Ferrarese-Filho, Osvaldo, Constantin, Rodrigo Polimeni

Publikováno v: In Toxicology Letters 1 July 2023 383:1-16

The photosensitiser azure A disrupts mitochondrial bioenergetics through intrinsic and photodynamic effects

Autor: de Souza, Byanca Thais Lima, Klosowski, Eduardo Makiyama, Mito, Márcio Shigueaki, Constantin, Renato Polimeni, Mantovanelli, Gislaine Cristiane, Mewes, Juliana Morais, Bizerra, Paulo Francisco Veiga, da Silva, Fernanda Sayuri Itou, Menezes, Paulo Vinicius Moreira da Costa, Gilglioni, Eduardo Hideo, Utsunomiya, Karina Sayuri, Marchiosi, Rogério, dos Santos, Wanderley Dantas, Ferrarese-Filho, Osvaldo, Caetano, Wilker, de Souza Pereira, Paulo Cesar, Gonçalves, Renato Sonchini, Constantin, Jorgete, Ishii-Iwamoto, Emy Luiza, Constantin, Rodrigo Polimeni ^*

Publikováno v: In Toxicology 15 May 2021 455

Toluidine blue O directly and photodynamically impairs the bioenergetics of liver mitochondria: a potential mechanism of hepatotoxicity.

Autor: dos Santos, Karina Borba Paulino, Raimundo, Ana Flavia Gatto, Klosowski, Eduardo Makiyama, de Souza, Byanca Thais Lima, Mito, Márcio Shigueaki, Constantin, Renato Polimeni, Mantovanelli, Gislaine Cristiane, Mewes, Juliana Morais, Bizerra, Paulo Francisco Veiga, da Costa Menezes, Paulo Vinicius Moreira, Utsunomiya, Karina Sayuri, Gilglioni, Eduardo Hideo, Marchiosi, Rogério, dos Santos, Wanderley Dantas, Ferrarese-Filho, Osvaldo, Caetano, Wilker, de Souza Pereira, Paulo Cesar, Gonçalves, Renato Sonchini, Constantin, Jorgete, Ishii-Iwamoto, Emy Luiza

Publikováno v: Photochemical & Photobiological Sciences; Feb2023, Vol. 22 Issue 2, p279-302, 24p

Unraveling the intrinsic and photodynamic effects of aluminum chloride phthalocyanine on bioenergetics and oxidative state in rat liver mitochondria.

Autor: Klosowski EM; Department of Biochemistry, Laboratory of Biological Oxidations, State University of Maringá, Maringá 87020-900, Paraná, Brazil., de Souza BTL; Department of Biochemistry, Laboratory of Biological Oxidations, State University of Maringá, Maringá 87020-900, Paraná, Brazil., Nanami LF; Department of Biochemistry, Laboratory of Biological Oxidations, State University of Maringá, Maringá 87020-900, Paraná, Brazil., Bizerra PFV; Department of Biochemistry, Laboratory of Biological Oxidations, State University of Maringá, Maringá 87020-900, Paraná, Brazil., Mito MS; Department of Biochemistry, Laboratory of Biological Oxidations, State University of Maringá, Maringá 87020-900, Paraná, Brazil., Esquissato GNM; Department of Biochemistry, Laboratory of Biological Oxidations, State University of Maringá, Maringá 87020-900, Paraná, Brazil. Electronic address: gnmesquissato2@uem.br., Constantin RP; Department of Biochemistry, Laboratory of Plant Biochemistry, State University of Maringá, Maringá 87020-900, Paraná, Brazil., Joia BM; Department of Biochemistry, Laboratory of Plant Biochemistry, State University of Maringá, Maringá 87020-900, Paraná, Brazil., Menezes PVMDC; Department of Physiological Sciences, State University of Maringá, Maringá 87020-900, Paraná, Brazil., Caetano W; Department of Chemistry, Research Nucleus in Photodynamic System, State University of Maringá, Maringá 87020-900, Paraná, Brazil. Electronic address: wcaetano@uem.br., Pereira PCS; Department of Chemistry, Research Nucleus in Photodynamic System, State University of Maringá, Maringá 87020-900, Paraná, Brazil., Gonçalves RS; Department of Chemistry, Research Nucleus in Photodynamic System, State University of Maringá, Maringá 87020-900, Paraná, Brazil. Electronic address: rsgoncalves2@uem.br., Garcia FP; Department of Basic Health Sciences, Laboratory of Technological Innovation in the Development of Pharmaceuticals and Cosmetics, State University of Maringá, Maringá 87020-900, Paraná, Brazil. Electronic address: fpgarcia2@uem.br., Bidoia DL; Department of Basic Health Sciences, Laboratory of Technological Innovation in the Development of Pharmaceuticals and Cosmetics, State University of Maringá, Maringá 87020-900, Paraná, Brazil. Electronic address: dlbidoia2@uem.br., Nakamura TU; Department of Basic Health Sciences, Laboratory of Technological Innovation in the Development of Pharmaceuticals and Cosmetics, State University of Maringá, Maringá 87020-900, Paraná, Brazil. Electronic address: tunakamura@uem.br., Nakamura CV; Department of Basic Health Sciences, Laboratory of Technological Innovation in the Development of Pharmaceuticals and Cosmetics, State University of Maringá, Maringá 87020-900, Paraná, Brazil. Electronic address: cvnakamura@uem.br., Ishii-Iwamoto EL; Department of Biochemistry, Laboratory of Biological Oxidations, State University of Maringá, Maringá 87020-900, Paraná, Brazil. Electronic address: eliiwamoto@uem.br., Dos Santos WD; Department of Biochemistry, Laboratory of Plant Biochemistry, State University of Maringá, Maringá 87020-900, Paraná, Brazil. Electronic address: wdsantos@uem.br., Ferrarese-Filho O; Department of Biochemistry, Laboratory of Plant Biochemistry, State University of Maringá, Maringá 87020-900, Paraná, Brazil. Electronic address: oferrarese@uem.br., Marchiosi R; Department of Biochemistry, Laboratory of Plant Biochemistry, State University of Maringá, Maringá 87020-900, Paraná, Brazil. Electronic address: rmarchiosi@uem.br., Constantin RP; Department of Biochemistry, Laboratory of Biological Oxidations, State University of Maringá, Maringá 87020-900, Paraná, Brazil; Department of Biochemistry, Laboratory of Plant Biochemistry, State University of Maringá, Maringá 87020-900, Paraná, Brazil. Electronic address: rpconstantin@uem.br.

Publikováno v: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2024 Nov 17; Vol. 494, pp. 117157. Date of Electronic Publication: 2024 Nov 17.