The DNA Sensor AIM2 Protects against Streptozotocin-Induced Type 1 Diabetes by Regulating Intestinal Homeostasis via the IL-18 Pathway.

Autor: Leite JA; Department of Biochemistry and Immunology, Ribeirão Preto Medical School, USP-Avenida Bandeirantes 3900, Monte Alegre, Ribeirão Preto, São Paulo 14049-900, Brazil.; Institute of Biomedical Science IV-University of São Paulo (USP), São Paulo, São Paulo 14049-900, Brazil., Pessenda G; Department of Biochemistry and Immunology, Ribeirão Preto Medical School, USP-Avenida Bandeirantes 3900, Monte Alegre, Ribeirão Preto, São Paulo 14049-900, Brazil., Guerra-Gomes IC; Department of Biochemistry and Immunology, Ribeirão Preto Medical School, USP-Avenida Bandeirantes 3900, Monte Alegre, Ribeirão Preto, São Paulo 14049-900, Brazil., de Santana AKM; Department of Biochemistry and Immunology, Ribeirão Preto Medical School, USP-Avenida Bandeirantes 3900, Monte Alegre, Ribeirão Preto, São Paulo 14049-900, Brazil., André Pereira C; Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, São Paulo 14049-900, Brazil., Ribeiro Campos Costa F; Department of Biochemistry and Immunology, Ribeirão Preto Medical School, USP-Avenida Bandeirantes 3900, Monte Alegre, Ribeirão Preto, São Paulo 14049-900, Brazil., Ramos SG; Department of Pathology and Legal Medicine, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, São Paulo 14049-900, Brazil., Simões Zamboni D; Department of Molecular and Cell Biology, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, São Paulo 14049-900, Brazil., Caetano Faria AM; Department of Biochemistry and Immunology, Institute of Biological Science-Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais 31270-901, Brazil., Candido de Almeida D; Department of Immunology-Federal University of São Paulo (UNIFESP), São Paulo, São Paulo 04021-001, Brazil., Olsen Saraiva Câmara N; Department of Biochemistry and Immunology, Ribeirão Preto Medical School, USP-Avenida Bandeirantes 3900, Monte Alegre, Ribeirão Preto, São Paulo 14049-900, Brazil.; Institute of Biomedical Science IV-University of São Paulo (USP), São Paulo, São Paulo 14049-900, Brazil.; Department of Immunology-Federal University of São Paulo (UNIFESP), São Paulo, São Paulo 04021-001, Brazil., Tostes RC; Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, São Paulo 14049-900, Brazil., Santana Silva J; Fiocruz- Bi-Institutional Translational Medicine Platform, Ribeirão Preto, São Paulo 14049-900, Brazil., Carlos D; Department of Biochemistry and Immunology, Ribeirão Preto Medical School, USP-Avenida Bandeirantes 3900, Monte Alegre, Ribeirão Preto, São Paulo 14049-900, Brazil.

Publikováno v: Cells [Cells] 2020 Apr 14; Vol. 9 (4). Date of Electronic Publication: 2020 Apr 14.