Single-cell RNA sequencing of cystic fibrosis liver disease explants reveals endothelial complement activation.

Autor: Declercq M; Department of Development and Regeneration, Woman and Child Unit, KU Leuven, Leuven, Belgium.; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven, Belgium., Treps L; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven, Belgium.; Nantes Université, INSERM UMR 1307, CNRS UMR 6075, Université d'Angers, CRCI2NA, Nantes, France., Geldhof V; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven, Belgium., Conchinha NV; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven, Belgium.; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal., de Rooij LPMH; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven, Belgium.; The CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Subramanian A; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven, Belgium.; Department of Biotechnology, Indian Institute of Technology, Hyderabad, Telangana, India., Feyeux M; Nantes Université, CHU Nantes, CNRS, Inserm, BioCore, US16, SFR Bonamy, Nantes, France., Cotinat M; Nantes Université, INSERM UMR 1307, CNRS UMR 6075, Université d'Angers, CRCI2NA, Nantes, France., Boeckx B; Laboratory for Translational Genetics, Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory for Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium., Vinckier S; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven, Belgium., Dupont L; Department of Pneumology, UZ Leuven, Leuven, Belgium.; Department of Chronic Diseases and Metabolism, Respiratory Diseases and Thoracic Surgery, KU Leuven, Leuven, Belgium., Vermeulen F; Department of Development and Regeneration, Woman and Child Unit, KU Leuven, Leuven, Belgium.; Department of Pediatrics, Pediatric Pulmonology, University Hospital of Leuven, Leuven, Flanders, Belgium., Boon M; Department of Development and Regeneration, Woman and Child Unit, KU Leuven, Leuven, Belgium.; Department of Pediatrics, Pediatric Pulmonology, University Hospital of Leuven, Leuven, Flanders, Belgium., Proesmans M; Department of Development and Regeneration, Woman and Child Unit, KU Leuven, Leuven, Belgium.; Department of Pediatrics, Pediatric Pulmonology, University Hospital of Leuven, Leuven, Flanders, Belgium., Libbrecht L; Department of Pathology, Cliniques Universitaires Saint-Luc, Brussels, Belgium.; Department of Pathology, AZ Groeninge, Kortrijk, Belgium.; Laboratory of Hepatology, KU Leuven, Leuven, Belgium., Pirenne J; Transplantation Research Group, Department of Immunology, Microbiology and Transplantation, KU Leuven, Leuven, Belgium.; Department of Abdominal Transplant Surgery, University Hospitals Leuven, Leuven, Belgium., Monbaliu D; Transplantation Research Group, Department of Immunology, Microbiology and Transplantation, KU Leuven, Leuven, Belgium.; Department of Abdominal Transplant Surgery, University Hospitals Leuven, Leuven, Belgium., Jochmans I; Transplantation Research Group, Department of Immunology, Microbiology and Transplantation, KU Leuven, Leuven, Belgium.; Department of Abdominal Transplant Surgery, University Hospitals Leuven, Leuven, Belgium., Dewerchin M; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven, Belgium., Eelen G; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven, Belgium., Roskams T; Department of Imaging and Pathology, Translational Cell and Tissue Research, KU Leuven and University Hospitals Leuven, Leuven, Belgium., Verleden S; Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), Department CHROMETA, KU Leuven, Leuven, Belgium.; Department of ASTARC, University of Antwerp, Wilrijk, Belgium., Lambrechts D; Laboratory for Translational Genetics, Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory for Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium., Carmeliet P; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven, Belgium.; Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, United Arab Emirates., Witters P; Department of Development and Regeneration, Woman and Child Unit, KU Leuven, Leuven, Belgium.; Department of Paediatrics and Metabolic Center, University Hospitals Leuven, Leuven, Belgium.

Publikováno v: Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2024 Sep; Vol. 44 (9), pp. 2382-2395. Date of Electronic Publication: 2024 Jun 07.

Transcriptomic signatures of progressive and regressive liver fibrosis and portal hypertension.

Autor: Petrenko O; Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna 1090, Austria.; Christian Doppler Laboratory for Portal Hypertension and Liver Fibrosis, Medical University of Vienna, Vienna 1090, Austria.; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna 1090, Austria., Königshofer P; Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna 1090, Austria.; Christian Doppler Laboratory for Portal Hypertension and Liver Fibrosis, Medical University of Vienna, Vienna 1090, Austria.; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna 1090, Austria., Brusilovskaya K; Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna 1090, Austria.; Christian Doppler Laboratory for Portal Hypertension and Liver Fibrosis, Medical University of Vienna, Vienna 1090, Austria.; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna 1090, Austria., Hofer BS; Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna 1090, Austria.; Christian Doppler Laboratory for Portal Hypertension and Liver Fibrosis, Medical University of Vienna, Vienna 1090, Austria.; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna 1090, Austria., Bareiner K; Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna 1090, Austria., Simbrunner B; Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna 1090, Austria.; Christian Doppler Laboratory for Portal Hypertension and Liver Fibrosis, Medical University of Vienna, Vienna 1090, Austria.; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna 1090, Austria., Jühling F; Université de Strasbourg, Inserm, Institut de Recherche sur les Maladies Virales et Hepatiques UMR_S1110, Strasbourg 67000, France., Baumert TF; Université de Strasbourg, Inserm, Institut de Recherche sur les Maladies Virales et Hepatiques UMR_S1110, Strasbourg 67000, France.; Service d'hépato-gastroentérologie, Hôpitaux Universitaires de Strasbourg, Strasbourg 67000, France.; Institut Universitaire de France (IUF), 75005 Paris, France., Lupberger J; Université de Strasbourg, Inserm, Institut de Recherche sur les Maladies Virales et Hepatiques UMR_S1110, Strasbourg 67000, France.; Service d'hépato-gastroentérologie, Hôpitaux Universitaires de Strasbourg, Strasbourg 67000, France.; Institut Universitaire de France (IUF), 75005 Paris, France., Trauner M; Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna 1090, Austria., Kauschke SG; Department of CardioMetabolic Diseases Research, Boehringer Ingelheim Pharma GmbH & Co.KG, 88397 Biberach an der Riss, Germany., Pfisterer L; Department of CardioMetabolic Diseases Research, Boehringer Ingelheim Pharma GmbH & Co.KG, 88397 Biberach an der Riss, Germany., Simon E; Global Computational Biology and Digital Sciences, Boehringer Ingelheim Pharma GmbH & Co.KG, 88397 Biberach an der Riss, Germany., Rendeiro AF; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna 1090, Austria., de Rooij LPMH; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna 1090, Austria., Schwabl P; Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna 1090, Austria.; Christian Doppler Laboratory for Portal Hypertension and Liver Fibrosis, Medical University of Vienna, Vienna 1090, Austria.; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna 1090, Austria., Reiberger T; Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna 1090, Austria.; Christian Doppler Laboratory for Portal Hypertension and Liver Fibrosis, Medical University of Vienna, Vienna 1090, Austria.; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna 1090, Austria.

Publikováno v: IScience [iScience] 2024 Feb 20; Vol. 27 (3), pp. 109301. Date of Electronic Publication: 2024 Feb 20 (Print Publication: 2024).

Neuroepithelial organoid patterning is mediated by a neighborhood watch mechanism.

Autor: Abdel Fattah AR; Laboratory of Bioengineering and Morphogenesis, Biomechanics Section, Department of Mechanical Engineering, KU Leuven, Leuven, Belgium., Grebenyuk S; Laboratory of Bioengineering and Morphogenesis, Biomechanics Section, Department of Mechanical Engineering, KU Leuven, Leuven, Belgium., de Rooij LPMH; Laboratory of Bioengineering and Morphogenesis, Biomechanics Section, Department of Mechanical Engineering, KU Leuven, Leuven, Belgium., Salmon I; Laboratory of Bioengineering and Morphogenesis, Biomechanics Section, Department of Mechanical Engineering, KU Leuven, Leuven, Belgium., Ranga A; Laboratory of Bioengineering and Morphogenesis, Biomechanics Section, Department of Mechanical Engineering, KU Leuven, Leuven, Belgium. Electronic address: adrian.ranga@kuleuven.be.

Publikováno v: Cell reports [Cell Rep] 2023 Nov 28; Vol. 42 (11), pp. 113334. Date of Electronic Publication: 2023 Oct 28.

The pulmonary vasculature in lethal COVID-19 and idiopathic pulmonary fibrosis at single-cell resolution.

Autor: de Rooij LPMH; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven 3000, Belgium., Becker LM; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven 3000, Belgium., Teuwen LA; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven 3000, Belgium., Boeckx B; Laboratory of Translational Genetics, Center for Cancer Biology, VIB & Department of Genetics, KU Leuven, Leuven 3000, Belgium., Jansen S; Laboratory of Virology & Chemotherapy, KU Leuven, Leuven 3000, Belgium., Feys S; Medical Intensive Care Unit, UZ Gasthuisberg & Laboratory for Clinical Infectious and Inflammatory Disorders, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven 3000, Belgium., Verleden S; Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), KU Leuven, Leuven 3000, Belgium., Liesenborghs L; Laboratory of Virology & Chemotherapy, KU Leuven, Leuven 3000, Belgium., Stalder AK; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel 4031, Switzerland., Libbrecht S; Department of Pathology, Ghent University Hospital, Ghent University, Ghent 9000, Belgium., Van Buyten T; Laboratory of Virology & Chemotherapy, KU Leuven, Leuven 3000, Belgium., Philips G; Laboratory of Translational Genetics, Center for Cancer Biology, VIB & Department of Genetics, KU Leuven, Leuven 3000, Belgium., Subramanian A; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven 3000, Belgium., Dumas SJ; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven 3000, Belgium., Meta E; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven 3000, Belgium., Borri M; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven 3000, Belgium., Sokol L; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven 3000, Belgium., Dendooven A; Department of Pathology, Ghent University Hospital, Ghent University, Ghent 9000, Belgium.; University of Antwerp, Faculty of Medicine, Wilrijk 2610, Belgium., Truong AK; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven 3000, Belgium., Gunst J; Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Leuven 3000, Belgium., Van Mol P; Laboratory of Translational Genetics, Center for Cancer Biology, VIB & Department of Genetics, KU Leuven, Leuven 3000, Belgium., Haslbauer JD; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, VIB, Leuven 3000, Belgium., Rohlenova K; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven 3000, Belgium., Menter T; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel 4031, Switzerland., Boudewijns R; Laboratory of Virology & Chemotherapy, KU Leuven, Leuven 3000, Belgium., Geldhof V; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven 3000, Belgium., Vinckier S; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven 3000, Belgium., Amersfoort J; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven 3000, Belgium., Wuyts W; Department of Respiratory Medicine, Unit for Interstitial Lung Diseases, UZ Gasthuisberg, Leuven 3000, Belgium., Van Raemdonck D; Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), KU Leuven, Leuven 3000, Belgium., Jacobs W; Medical CBRNe unit, Queen Astrid Military Hospital, Belgian Defense, Neder-Over-Heembeek 1120, Belgium.; Department of Forensic Pathology, ASTARC Antwerp University Hospital and University of Antwerp, Antwerp 2610, Belgium., Ceulemans LJ; Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), KU Leuven, Leuven 3000, Belgium., Weynand B; Translational Cell & Tissue Research, Department of Imaging & Pathology, KU Leuven, Leuven 3000, Belgium., Thienpont B; Laboratory for Functional Epigenetics, Department of Human Genetics, KU Leuven, Leuven 3000, Belgium., Lammens M; Department of Pathology Antwerp University Hospital, Edegem 2560, Belgium.; Center for Oncological Research, University of Antwerp, Antwerp 2000, Belgium., Kuehnel M; Medizinische Hochschule Hannover (MHH), Institut für Pathologie, D-30625 Hannover, Germany.; Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH) Member of the German Centre for Lung research (DZL), Hannover 30625, Germany., Eelen G; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven 3000, Belgium., Dewerchin M; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven 3000, Belgium., Schoonjans L; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven 3000, Belgium.; Laboratory of Translational Genetics, Center for Cancer Biology, VIB & Department of Genetics, KU Leuven, Leuven 3000, Belgium., Jonigk D; Medizinische Hochschule Hannover (MHH), Institut für Pathologie, D-30625 Hannover, Germany.; Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH) Member of the German Centre for Lung research (DZL), Hannover 30625, Germany., van Dorpe J; Department of Pathology, Ghent University Hospital, Ghent University, Ghent 9000, Belgium., Tzankov A; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel 4031, Switzerland., Wauters E; Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), KU Leuven, Leuven 3000, Belgium.; Respiratory Oncology Unit, University Hospital KU Leuven, Leuven 3000, Belgium., Mazzone M; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, VIB, Leuven 3000, Belgium.; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, Department of Oncology, KU Leuven, Leuven 3000, Belgium., Neyts J; Laboratory of Virology & Chemotherapy, KU Leuven, Leuven 3000, Belgium., Wauters J; Medical Intensive Care Unit, UZ Gasthuisberg & Laboratory for Clinical Infectious and Inflammatory Disorders, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven 3000, Belgium., Lambrechts D; Laboratory of Translational Genetics, Center for Cancer Biology, VIB & Department of Genetics, KU Leuven, Leuven 3000, Belgium., Carmeliet P; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, VIB, Leuven 3000, Belgium.; Laboratory of Angiogenesis and Vascular Heterogeneity, Department of Biomedicine, Aarhus University, Aarhus 8000, Denmark.; Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, United Arab Emirates.

Publikováno v: Cardiovascular research [Cardiovasc Res] 2023 Mar 31; Vol. 119 (2), pp. 520-535.

Generation of vessel co-option lung metastases mouse models for single-cell isolation of metastases-derived cells and endothelial cells.

Autor: Cuypers A; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology (CCB), VIB, Department of Oncology, Leuven Cancer Institute, KU Leuven, 3000 Leuven, Belgium., Teuwen LA; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology (CCB), VIB, Department of Oncology, Leuven Cancer Institute, KU Leuven, 3000 Leuven, Belgium; Translational Cancer Research Unit, GZA Hospitals Sint-Augustinus, 2610 Antwerp, Belgium; Center for Oncological Research, University of Antwerp, 2000 Antwerp, Belgium., Bridgeman VL; Tumour Host Interaction Laboratory, The Francis Crick Institute, London NW1 1AT, UK., de Rooij LPMH; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology (CCB), VIB, Department of Oncology, Leuven Cancer Institute, KU Leuven, 3000 Leuven, Belgium., Eelen G; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology (CCB), VIB, Department of Oncology, Leuven Cancer Institute, KU Leuven, 3000 Leuven, Belgium., Dewerchin M; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology (CCB), VIB, Department of Oncology, Leuven Cancer Institute, KU Leuven, 3000 Leuven, Belgium., Cantelmo AR; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology (CCB), VIB, Department of Oncology, Leuven Cancer Institute, KU Leuven, 3000 Leuven, Belgium., Kalucka J; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology (CCB), VIB, Department of Oncology, Leuven Cancer Institute, KU Leuven, 3000 Leuven, Belgium., Bouché A; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology (CCB), VIB, Department of Oncology, Leuven Cancer Institute, KU Leuven, 3000 Leuven, Belgium., Vinckier S; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology (CCB), VIB, Department of Oncology, Leuven Cancer Institute, KU Leuven, 3000 Leuven, Belgium., Carton A; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology (CCB), VIB, Department of Oncology, Leuven Cancer Institute, KU Leuven, 3000 Leuven, Belgium., Manderveld A; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology (CCB), VIB, Department of Oncology, Leuven Cancer Institute, KU Leuven, 3000 Leuven, Belgium., Vermeulen PB; Translational Cancer Research Unit, GZA Hospitals Sint-Augustinus, 2610 Antwerp, Belgium; Center for Oncological Research, University of Antwerp, 2000 Antwerp, Belgium., Reynolds AR; Oncology R&D, AstraZeneca, Cambridge CB2 0AA, UK., Carmeliet P; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology (CCB), VIB, Department of Oncology, Leuven Cancer Institute, KU Leuven, 3000 Leuven, Belgium; Laboratory of Angiogenesis and Vascular Heterogeneity, Department of Biomedicine, Aarhus University, 8000 Aarhus, Denmark; Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi 127788, United Arab Emirates. Electronic address: peter.carmeliet@kuleuven.be.

Publikováno v: STAR protocols [STAR Protoc] 2022 Dec 16; Vol. 3 (4), pp. 101691. Date of Electronic Publication: 2022 Sep 28.