Characterization of Triptolide-Induced Hepatotoxicity by Imaging and Transcriptomics in a Novel Zebrafish Model.

Autor: Vliegenthart ADB; Edinburgh University/BHF Centre for Cardiovascular Science, The Queen's Medical Research Institute, Edinburgh EH16?4TJ, UK., Wei C; Edinburgh University/BHF Centre for Cardiovascular Science, The Queen's Medical Research Institute, Edinburgh EH16 4TJ, UK.; Center for Drug Evaluation, China Food and Drug Agency, Beijing 100083, China., Buckley C; Edinburgh University/BHF Centre for Cardiovascular Science, The Queen's Medical Research Institute, Edinburgh EH16?4TJ, UK., Berends C; Edinburgh University/BHF Centre for Cardiovascular Science, The Queen's Medical Research Institute, Edinburgh EH16?4TJ, UK., de Potter CMJ; Edinburgh University/BHF Centre for Cardiovascular Science, The Queen's Medical Research Institute, Edinburgh EH16?4TJ, UK., Schneemann S; Edinburgh University/BHF Centre for Cardiovascular Science, The Queen's Medical Research Institute, Edinburgh EH16?4TJ, UK., Del Pozo J; Easter Bush Pathology, Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Easter Bush Campus, Roslin, Midlothian EH25?9RG, UK., Tucker C; Biomedical Research Resources, The College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh EH16?4TJ, UK., Mullins JJ; Edinburgh University/BHF Centre for Cardiovascular Science, The Queen's Medical Research Institute, Edinburgh EH16?4TJ, UK., Webb DJ; Edinburgh University/BHF Centre for Cardiovascular Science, The Queen's Medical Research Institute, Edinburgh EH16?4TJ, UK., Dear JW; Edinburgh University/BHF Centre for Cardiovascular Science, The Queen's Medical Research Institute, Edinburgh EH16?4TJ, UK.

Publikováno v: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2017 Oct 01; Vol. 159 (2), pp. 380-391.