Blocking IL-10 signaling with soluble IL-10 receptor restores in vitro specific lymphoproliferative response in dogs with leishmaniasis caused by Leishmania infantum.

Autor: Santos CO; Oswaldo Cruz Foundation, Gonçalo Moniz Research Center, Laboratory of Structural and Molecular Pathology (LAPEM), Tissue Engineering and Immunopharmacology Laboratory (LETI) or Pathology and Molecular Biology Laboratory (LPBM), Candeal, Salvador, Brazil., Costa SF; Department of Clinical Medicine, Surgery and Animal Reproduction, São Paulo State University (UNESP), School of Veterinary Medicine, Araçatuba, Brazil., Souza FS; Oswaldo Cruz Foundation, Gonçalo Moniz Research Center, Laboratory of Structural and Molecular Pathology (LAPEM), Tissue Engineering and Immunopharmacology Laboratory (LETI) or Pathology and Molecular Biology Laboratory (LPBM), Candeal, Salvador, Brazil., Mendes JMF; Oswaldo Cruz Foundation, Gonçalo Moniz Research Center, Laboratory of Structural and Molecular Pathology (LAPEM), Tissue Engineering and Immunopharmacology Laboratory (LETI) or Pathology and Molecular Biology Laboratory (LPBM), Candeal, Salvador, Brazil., de Pinheiro CGM; Oswaldo Cruz Foundation, Gonçalo Moniz Research Center, Laboratory of Structural and Molecular Pathology (LAPEM), Tissue Engineering and Immunopharmacology Laboratory (LETI) or Pathology and Molecular Biology Laboratory (LPBM), Candeal, Salvador, Brazil., Moreira DRM; Oswaldo Cruz Foundation, Gonçalo Moniz Research Center, Laboratory of Structural and Molecular Pathology (LAPEM), Tissue Engineering and Immunopharmacology Laboratory (LETI) or Pathology and Molecular Biology Laboratory (LPBM), Candeal, Salvador, Brazil., Silva LK; Oswaldo Cruz Foundation, Gonçalo Moniz Research Center, Laboratory of Structural and Molecular Pathology (LAPEM), Tissue Engineering and Immunopharmacology Laboratory (LETI) or Pathology and Molecular Biology Laboratory (LPBM), Candeal, Salvador, Brazil., de Lima VMF; Department of Clinical Medicine, Surgery and Animal Reproduction, São Paulo State University (UNESP), School of Veterinary Medicine, Araçatuba, Brazil., de Sá Oliveira GG; Oswaldo Cruz Foundation, Gonçalo Moniz Research Center, Laboratory of Structural and Molecular Pathology (LAPEM), Tissue Engineering and Immunopharmacology Laboratory (LETI) or Pathology and Molecular Biology Laboratory (LPBM), Candeal, Salvador, Brazil.

Publikováno v: PloS one [PLoS One] 2021 Jan 19; Vol. 16 (1), pp. e0239171. Date of Electronic Publication: 2021 Jan 19 (Print Publication: 2021).