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An epoxide hydrolase from endophytic Streptomyces shows unique structural features and wide biocatalytic activity.

Autor: Tormet-González, Gabriela D., Wilson, Carolina, de Oliveira, Gabriel Stephani, dos Santos, Jademilson Celestino, de Oliveira, Luciana G., Dias, Marcio Vinicius Bertacine

Publikováno v: Acta Crystallographica: Section D, Structural Biology; Sep2020, Vol. 76 Issue 9, p868-875, 8p

Zileuton, a 5-Lypoxigenase Inhibitor, is Antiparasitic and Prevents Inflammation in the Chronic Stage of Heart Chagas Disease.

Autor: Ricci MF; Department of Biochemistry and Immunology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Minas Gerais, Brazil., Lourenço EMG; Department of Biochemistry and Immunology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Minas Gerais, Brazil., Pereira RDD; Department of Biochemistry and Immunology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Minas Gerais, Brazil., Araújo RRS; Department of Biochemistry and Immunology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Minas Gerais, Brazil., Oliveira FBR; Department of Biochemistry and Immunology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Minas Gerais, Brazil., Barbosa da Silva E; Department of Biochemistry and Immunology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Minas Gerais, Brazil., de Oliveira GS; Department of Microbiology, Institute of Biomedical Sciences, Universidade de São Paulo, São Paulo 05508-000, Brazil., Teixeira MM; Department of Biochemistry and Immunology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Minas Gerais, Brazil.; Program in Health Sciences: Infectious Diseases and Tropical Medicine/Interdisciplinary Laboratory of Medical Investigation, Faculty of Medicine, Universidade Federal de Minas Gerais, Belo Horizonte 30130-100, Minas Gerais, Brazil., Rocha NN; Department of Physiology and Pharmacology, Biomedical Institute, Universidade Federal Fluminense, Niterói 24020-141, Rio de Janeiro, Brazil., Chambergo FS; School of Arts, Sciences and Humanities, Universidade de São Paulo, São Paulo 03828-000, Brazil., Roman-Campos D; Department of Biophysics, Universidade Federal de São Paulo, São Paulo 04023-062, Brazil., Cruz JS; Department of Biochemistry and Immunology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Minas Gerais, Brazil., Ferreira RS; Department of Biochemistry and Immunology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Minas Gerais, Brazil., Machado FS; Department of Biochemistry and Immunology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Minas Gerais, Brazil.; Program in Health Sciences: Infectious Diseases and Tropical Medicine/Interdisciplinary Laboratory of Medical Investigation, Faculty of Medicine, Universidade Federal de Minas Gerais, Belo Horizonte 30130-100, Minas Gerais, Brazil.

Publikováno v: ACS infectious diseases [ACS Infect Dis] 2024 Nov 28. Date of Electronic Publication: 2024 Nov 28.