Lorcaserin improves glycemic control via a melanocortin neurocircuit.

Autor: Burke LK; Department of Pharmacology, University of Cambridge, Cambridge, UK; Department of Medicine and Wellcome Trust/MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Ogunnowo-Bada E; Department of Medicine and Wellcome Trust/MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Georgescu T; The Rowett Institute, University of Aberdeen, Aberdeen, UK., Cristiano C; The Rowett Institute, University of Aberdeen, Aberdeen, UK., de Morentin PBM; The Rowett Institute, University of Aberdeen, Aberdeen, UK., Valencia Torres L; Department of Pharmacology, University of Cambridge, Cambridge, UK; The Rowett Institute, University of Aberdeen, Aberdeen, UK., D'Agostino G; Department of Pharmacology, University of Cambridge, Cambridge, UK; The Rowett Institute, University of Aberdeen, Aberdeen, UK., Riches C; Department of Medicine and Wellcome Trust/MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Heeley N; Department of Medicine and Wellcome Trust/MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Ruan Y; Department of Medicine and Wellcome Trust/MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Rubinstein M; Instituto de Investigaciones en Ingeniería Genética y Biología Molecular, Consejo Nacional de Investigaciones Científicas y Técnicas, 1428 Buenos Aires, Argentina., Low MJ; Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, MI, USA., Myers MG; Division of Metabolism, Endocrinology, and Diabetes, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA., Rochford JJ; The Rowett Institute, University of Aberdeen, Aberdeen, UK., Evans ML; Department of Medicine and Wellcome Trust/MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK. Electronic address: mle24@cam.ac.uk., Heisler LK; Department of Pharmacology, University of Cambridge, Cambridge, UK; The Rowett Institute, University of Aberdeen, Aberdeen, UK. Electronic address: lora.heisler@abdn.ac.uk.

Publikováno v: Molecular metabolism [Mol Metab] 2017 Oct; Vol. 6 (10), pp. 1092-1102. Date of Electronic Publication: 2017 Jul 21.