A late-stage diversification via Heck-Matsuda arylation: Straightforward synthesis and cytotoxic/antiproliferative profiling of novel aryl-labdane-type derivatives.

Autor: de Souza-Ferrari J; Department of Chemistry, Federal University of Paraiba, Cidade Universitária, Campus I. CEP 58051-900, João Pessoa, Paraíba, Brazil. Electronic address: jferrari@quimica.ufpb.br., Silva-Júnior EA; Department of Chemistry, Federal University of Paraiba, Cidade Universitária, Campus I. CEP 58051-900, João Pessoa, Paraíba, Brazil., Vale JA; Department of Chemistry, Federal University of Paraiba, Cidade Universitária, Campus I. CEP 58051-900, João Pessoa, Paraíba, Brazil., de Albuquerque Simões LA; Department of Biotechnology, Federal University of Paraiba, Cidade Universitária, Campus I. CEP 58051-900, João Pessoa, Paraíba, Brazil., de Moraes-Júnior MO; Department of Biotechnology, Federal University of Paraiba, Cidade Universitária, Campus I. CEP 58051-900, João Pessoa, Paraíba, Brazil., Dantas BB; Department of Biotechnology, Federal University of Paraiba, Cidade Universitária, Campus I. CEP 58051-900, João Pessoa, Paraíba, Brazil., de Araújo DAM; Department of Biotechnology, Federal University of Paraiba, Cidade Universitária, Campus I. CEP 58051-900, João Pessoa, Paraíba, Brazil.

Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2021 Nov 15; Vol. 52, pp. 128393. Date of Electronic Publication: 2021 Oct 01.