The C‑Terminal VPRTES Tail of LL-37 Influences the Mode of Attachment to a Lipid Bilayer and Antimicrobial Activity.

Autor: de Miguel Catalina, Alejandra, Forbrig, Enrico, Kozuch, Jacek, Nehls, Christian, Paulowski, Laura, Gutsmann, Thomas, Hildebrandt, Peter, Mroginski, Maria Andrea

Publikováno v: Biochemistry; 5/14/2019, Vol. 58 Issue 19, p2447-2462, 16p

A Computational Modeling Approach Predicts Interaction of the Antifungal Protein AFP from Aspergillus giganteus with Fungal Membranes via Its γ-Core Motif.

Autor: Utesch T; Institut für Chemie, Technische Universität Berlin, Berlin, Germany., de Miguel Catalina A; Institut für Chemie, Technische Universität Berlin, Berlin, Germany., Schattenberg C; Institut für Chemie, Technische Universität Berlin, Berlin, Germany., Paege N; Institute of Biotechnology, Department Applied and Molecular Microbiology, Technische Universität Berlin, Berlin, Germany., Schmieder P; Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany., Krause E; Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany., Miao Y; Center for Computational Biology, University of Kansas, Lawrence, Kansas, USA.; Department of Molecular Biosciences, University of Kansas, Lawrence, Kansas, USA., McCammon JA; Department of Chemistry & Biochemistry, University of California, San Diego, La Jolla, California, USA.; Department of Pharmacology, University of California, San Diego, La Jolla, California, USA., Meyer V; Institute of Biotechnology, Department Applied and Molecular Microbiology, Technische Universität Berlin, Berlin, Germany., Jung S; Institute of Biotechnology, Department Applied and Molecular Microbiology, Technische Universität Berlin, Berlin, Germany., Mroginski MA; Institut für Chemie, Technische Universität Berlin, Berlin, Germany andrea.mroginski@tu-berlin.de.

Publikováno v: MSphere [mSphere] 2018 Oct 03; Vol. 3 (5). Date of Electronic Publication: 2018 Oct 03.