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pro vyhledávání: '"de Matas, Marcel"'
Autor:
Shah, S.M.H., Ullah, F., Khan, Shahzeb, Shah, S.M.M., de Matas, Marcel, Hussain, Z., Minhas, M.U., AbdEl-Salam, N.M., Assi, Khaled H., Isreb, Mohammad
Yes
Artemether (ARTM) is a very effective antimalarial drug with poor solubility and consequently low bioavailability. Smart nanocrystals of ARTM with particle size of 161±1.5 nm and polydispersity index of 0.172±0.01 were produced in
Artemether (ARTM) is a very effective antimalarial drug with poor solubility and consequently low bioavailability. Smart nanocrystals of ARTM with particle size of 161±1.5 nm and polydispersity index of 0.172±0.01 were produced in
Externí odkaz:
http://hdl.handle.net/10454/11037
Quality by design (QbD) is an essential part of the modern approach to pharmaceutical quality. This study was conducted in the framework of a QbD project involving ramipril tablets. Preliminary work included identification of the critical quality att
Externí odkaz:
http://hdl.handle.net/10454/10109
PURPOSE: To explore the use of crystal inter-planar d-spacings and slip-plane interaction energies for predicting and characterising mechanical properties of crystalline solids. METHODS: Potential relationships were evaluated between mechanical prope
Externí odkaz:
http://hdl.handle.net/10454/6184
Of particular importance in recent years has been the development of techniques for producing nanoparticles (NPs) of poorly-water soluble drugs with dimensions less than 1000 nm for which their high surface area can lead to improvements in bioavailab
Externí odkaz:
http://hdl.handle.net/10454/4835
Crystallisation is a widely used technique for purification and manipulation of the final crystal form of therapeutic agents. In particular, potential exists to control the mechanical properties of ibuprofen through control of crystal habit. The aim
Externí odkaz:
http://hdl.handle.net/10454/4834
The increasing prevalence of poorly soluble drugs in development provides notable risk of new products demonstrating low and erratic bioavailabilty with consequences for safety and efficacy, particularly for drugs delivered by the oral route of admin
Externí odkaz:
http://hdl.handle.net/10454/4844
Autor:
Richardson, Catherine H., de Matas, Marcel, Hosker, K., Mukherjee, R., Wong, Ian, Chrystyn, Henry
Purpose The relative lung bioavailability of salbutamol sulfate particles produced using supercritical fluids (SEDS¿) and delivered by dry powder inhaler (DPI) was compared with the performance of a conventional micronized drug DPI using the same de
Externí odkaz:
http://hdl.handle.net/10454/3813
The ability to generate predictive models linking the in vitro assessment of pharmaceutical products with in vivo performance has the potential to enable greater control of clinical quality whilst minimizing the number of in vivo studies in drug deve
Externí odkaz:
http://hdl.handle.net/10454/4161
Akademický článek
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Publikováno v:
Crystal Growth & Design; 11/6/2024, Vol. 24 Issue 21, p9297-9300, 4p
