Corticosteroids Do Not Reverse the Inhibitory Effect of Cyclosporine on Regulatory T-Cell Activity in Contrast to Mycophenolate Mofetil

Autor: Miroux, C., Morales, O., Ouaguia, L., Aoudjehane, L., Boleslawski, E., Pancré, V., de Launoit, Y., Calmus, Y., Conti, F., Delhem, N.

Publikováno v: In Transplantation Proceedings November 2012 44(9):2834-2839

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Viral oncoproteins target the DNA methyltransferases

Autor: Burgers, T, Blanchon, Loïc, Pradhan, S, de Launoit, Y, Kouzarides, T, Fuks, F, Burgers, W, Launoit, y De

Publikováno v: Oncogene
Oncogene, 2007, 26 (11), pp.1650-1655. ⟨10.1038/sj.onc.1209950⟩
Oncogene, Nature Publishing Group, 2007, 26 (11), pp.1650-1655. ⟨10.1038/sj.onc.1209950⟩

International audience; Small DNA tumour viruses have evolved a number of mechanisms to drive nondividing cells into S phase. Virally encoded oncoproteins such as adenovirus E1A and human papillomavirus (HPV) E7 can bind an array of cellular proteins

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dad3ba725d3b29f45198440919e2a70
https://doi.org/10.1038/sj.onc.1209950

Structure of the gene for the human 17β-hydroxysteroid dehydrogenase type IV

Autor: Dolez, Jerzy Adamski, Leenders F, Agnès Begue, Gloeckner Jc, de Launoit Y, Gabriele Möller

Publikováno v: Mammalian Genome. 9:1036-1041

The 17beta-hydroxysteroid dehydrogenase type IV (17beta-HSD IV) is a multifunctional enzyme that is localized in the peroxisomes. The N-terminal part has dehydrogenase activity, the central part has hydratase activity, and the carboxy-terminal part i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7588ae3bd3e614cbd73691577a342ca5
https://doi.org/10.1007/s003359900921

[Multiple post-translational modifications implied in the gene expression regulation: example of the sumoylation of Ets factors]

Autor: de Launoit Y, Degerny C, Alexandre Wohlkonig, Jl, Baert

Publikováno v: Europe PubMed Central

To regulate the spatiotemporal expression of their target genes, the transcription factors undergo post-translational modifications of which the most studied is phosphorylation. Acetylation and ubiquitinylation on lysine residues also exert a role in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::75c06eb4e9879e7a785a65e8f7aea615
https://pubmed.ncbi.nlm.nih.gov/18404999