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The interplay between densification and positional ordering during the process of crystal nucleation is a greatly investigated topic. Even for the simplest colloidal model -- hard spheres -- there has been much debate regarding the potential foreshad
Externí odkaz:
http://arxiv.org/abs/2407.10765
Autor:
de Jager, Marjolein, Vega, Carlos, de Hijes, Pablo Montero, Smallenburg, Frank, Filion, Laura
In the study of crystal nucleation via computer simulations, hard spheres are arguably the most extensively explored model system. Nonetheless, even in this simple model system, the complex thermodynamics of crystal nuclei can sometimes give rise to
Externí odkaz:
http://arxiv.org/abs/2407.04394
One method for computationally determining phase boundaries is to explicitly simulate a direct coexistence between the two phases of interest. Although this approach works very well for fluid-fluid coexistences, it is often considered to be less usef
Externí odkaz:
http://arxiv.org/abs/2403.10891
With the constant spread of misinformation on social media networks, a need has arisen to continuously assess the veracity of digital content. This need has inspired numerous research efforts on the development of misinformation detection (MD) models
Externí odkaz:
http://arxiv.org/abs/2312.04052
Autor:
Gomez-Sarmiento, Isaac Neri, Tho, Daline, Dürrbeck, Christopher, de Jager, Wim, Laurendeau, Denis, Beaulieu, Luc
Electromagnetic tracking (EMT) shows great potential for automating implant reconstruction in brachytherapy. One of the challenges of this technology is that it does not intrinsically share the same reference frame as the patient's medical imaging. T
Externí odkaz:
http://arxiv.org/abs/2308.02009
The interplay between crystal nucleation and the structure of the metastable fluid has been a topic of significant debate over recent years. In particular, it has been suggested that even in simple model systems such as hard or charged colloids, crys
Externí odkaz:
http://arxiv.org/abs/2306.05886
Autor:
Randy L. Parrish, Aron S. Buchman, Shinya Tasaki, Yanling Wang, Denis Avey, Jishu Xu, Philip L. De Jager, David A. Bennett, Michael P. Epstein, Jingjing Yang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Multiple reference panels of a given tissue or multiple tissues often exist, and multiple regression methods could be used for training gene expression imputation models for transcriptome-wide association studies (TWAS). To leverage expressi
Externí odkaz:
https://doaj.org/article/e1438fafdf334bde867c5aecd9114757
Single cell transcriptomes and multiscale networks from persons with and without Alzheimer’s disease
Autor:
Qi Wang, Jerry Antone, Eric Alsop, Rebecca Reiman, Cory Funk, Jaroslav Bendl, Joel T. Dudley, Winnie S. Liang, Timothy L. Karr, Panos Roussos, David A. Bennett, Philip L. De Jager, Geidy E. Serrano, Thomas G. Beach, Kendall Van Keuren-Jensen, Diego Mastroeni, Eric M. Reiman, Benjamin P. Readhead
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The emergence of single nucleus RNA sequencing (snRNA-seq) offers to revolutionize the study of Alzheimer’s disease (AD). Integration with complementary multiomics data such as genetics, proteomics and clinical data provides powerful oppor
Externí odkaz:
https://doaj.org/article/583e7a46c0434985a97259a70db5d4e3
Autor:
Carlijn A Hoekx, Borja Martinez-Tellez, Maaike E Straat, Magdalena M A Verkleij, Mirjam Kemmeren, Sander Kooijman, Martin Uhrbom, Saskia C A de Jager, Patrick C N Rensen, Mariëtte R Boon
Publikováno v:
Endocrine Connections, Vol 13, Iss 7, Pp 1-10 (2024)
Objectives: Cold exposure is linked to cardiometabolic benefits. Cold activates brown adipose tissue (BAT), increases energy expenditure, and induces secretion of the hormones fibroblast growth factor 21 (FGF21) and growth differentiation factor 15 (
Externí odkaz:
https://doaj.org/article/0be410fb04c2444f94093ce16ab04b39
Autor:
Vincent D. de Jager, Jos A. Stigt, Maarten Niemantsverdriet, Arja ter Elst, Anthonie J. van der Wekken
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-4 (2024)
Abstract Precision cancer medicine has changed the treatment paradigm of patients with non-small cell lung cancer (NSCLC) with specific molecular aberrations. A major challenge is management of the resistance that tumor cells eventually develop again
Externí odkaz:
https://doaj.org/article/66cbe8d1f3b64337b77a6fb34250db83