The Constrained Maximal Expression Level Owing to Haploidy Shapes Gene Content on the Mammalian X Chromosome

Autor: Hurst, LD, Ghanbarian, AT, Forrest, ARR, Huminiecki, L, Rehli, M, Kenneth Baillie, J, de Hoon, MJL, Haberle, V, Lassmann, T, Kulakovskiy, IV, Lizio, M, Itoh, M, Andersson, R, Mungall, CJ, Meehan, TF, Schmeier, S, Bertin, N, Jørgensen, M, Dimont, E, Arner, E, Schmidl, C, Schaefer, U, Medvedeva, YA, Plessy, C, Vitezic, M, Severin, J, Semple, CA, Ishizu, Y, Young, RS, Francescatto, M, Alam, I, Albanese, D, Altschuler, GM, Arakawa, T, Archer, JAC, Arner, P, Babina, M, Baker, S, Balwierz, PJ, Beckhouse, AG, Pradhan, SB, Blake, JA, Blumenthal, A, Bodega, B, Bonetti, A, Briggs, J, Brombacher, F, Maxwell Burroughs, A, Califano, A, Cannistraci, CV, Carbajo, D, Chen, Y, Chierici, M, Ciani, Y, Clevers, HC, Dalla, E, Davis, CA, Detmar, M, Diehl, AD, Dohi, T, Drabløs, F, Edge, ASB, Edinger, M, Ekwall, K, Endoh, M, Enomoto, H, Fagiolini, M, Fairbairn, L, Fang, H

Publikováno v: Hurst, LD; Ghanbarian, AT; Forrest, ARR; Huminiecki, L; Rehli, M; Kenneth Baillie, J; et al.(2015). The Constrained Maximal Expression Level Owing to Haploidy Shapes Gene Content on the Mammalian X Chromosome. PLoS Biology, 13(12). doi: 10.1371/journal.pbio.1002315. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/6m82k3gd

© 2015 Hurst et al. X chromosomes are unusual in many regards, not least of which is their nonrandom gene content. The causes of this bias are commonly discussed in the context of sexual antagonism and the avoidance of activity in the male germline.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::194414dad11085846528df656e8039b3
http://www.escholarship.org/uc/item/6m82k3gd

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Annotation of nuclear lncRNAs based on chromatin interactions.

Autor: Agrawal S; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Buyan A; Autosome.org, Russia.; FANTOM Consortium, Dolgoprudny, Russia., Severin J; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Koido M; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Institute of Medical Science, The University of Tokyo, Tokyo, Japan., Alam T; College of Science and Engineering, Hamad Bin Khalifa University, Doha, Qatar., Abugessaisa I; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Chang HY; Center for Personal Dynamic Regulome, Stanford University, Stanford, California, United States of America., Dostie J; Department of Biochemistry, Rosalind and Morris Goodman Cancer Research Center, McGill University, Montréal, Québec, Canada., Itoh M; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; RIKEN Preventive Medicine and Diagnosis Innovation Program, Wako, Japan., Kere J; Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden.; Stem Cells and Metabolism Research Program, University of Helsinki and Folkhälsan Research Center, Helsinki, Finland., Kondo N; RIKEN Center for Life Science Technologies, Yokohama, Japan., Li Y; Division of Biostatistics, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada., Makeev VJ; FANTOM Consortium, Dolgoprudny, Russia., Mendez M; Department of Computer Science, University of Toronto, Toronto, Ontario, Canada., Okazaki Y; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Ramilowski JA; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Advanced Medical Research Center, Yokohama City University, Yokohama, Japan., Sigorskikh AI; FANTOM Consortium, Dolgoprudny, Russia., Strug LJ; Division of Biostatistics, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.; Department of Computer Science, University of Toronto, Toronto, Ontario, Canada.; Department of Statistical Sciences, University of Toronto, Ontario, Canada.; The Centre for Applied Genomics and Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada., Yagi K; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Yasuzawa K; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Yip CW; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Hon CC; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Hoffman MM; Department of Computer Science, University of Toronto, Toronto, Ontario, Canada.; Princess Margaret Cancer Centre, Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.; Vector Institute, Toronto, Ontario, Canada., Terao C; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Kulakovskiy IV; Autosome.org, Russia.; FANTOM Consortium, Dolgoprudny, Russia., Kasukawa T; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Shin JW; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore., Carninci P; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Human Technopole, Milan, Italy., de Hoon MJL; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.

Publikováno v: PloS one [PLoS One] 2024 May 06; Vol. 19 (5), pp. e0295971. Date of Electronic Publication: 2024 May 06 (Print Publication: 2024).

The choice of negative control antisense oligonucleotides dramatically impacts downstream analysis depending on the cellular background.

Autor: Ducoli L; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology (ETH) Zurich, Vladimir-Prelog-Weg 3, 8093, Zurich, Switzerland.; Molecular Life Sciences PhD Program, Swiss Federal Institute of Technology and University of Zurich, Zurich, Switzerland., Agrawal S; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies, Yokohama, Kanagawa, 230-0045, Japan., Hon CC; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies, Yokohama, Kanagawa, 230-0045, Japan., Ramilowski JA; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies, Yokohama, Kanagawa, 230-0045, Japan., Sibler E; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology (ETH) Zurich, Vladimir-Prelog-Weg 3, 8093, Zurich, Switzerland.; Molecular Life Sciences PhD Program, Swiss Federal Institute of Technology and University of Zurich, Zurich, Switzerland., Tagami M; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies, Yokohama, Kanagawa, 230-0045, Japan., Itoh M; RIKEN Preventive Medicine and Diagnosis Innovation Program, RIKEN Center for Life Science Technologies, Yokohama, Kanagawa, 230-0045, Japan., Kondo N; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies, Yokohama, Kanagawa, 230-0045, Japan., Abugessaisa I; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies, Yokohama, Kanagawa, 230-0045, Japan., Hasegawa A; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies, Yokohama, Kanagawa, 230-0045, Japan., Kasukawa T; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies, Yokohama, Kanagawa, 230-0045, Japan., Suzuki H; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies, Yokohama, Kanagawa, 230-0045, Japan., Carninci P; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies, Yokohama, Kanagawa, 230-0045, Japan.; Human Technopole, Via Cristina Belgioioso 171, 20157, Milan, Italy., Shin JW; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies, Yokohama, Kanagawa, 230-0045, Japan., de Hoon MJL; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies, Yokohama, Kanagawa, 230-0045, Japan., Detmar M; Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology (ETH) Zurich, Vladimir-Prelog-Weg 3, 8093, Zurich, Switzerland. michael.detmar@pharma.ethz.ch.

Publikováno v: BMC genomic data [BMC Genom Data] 2021 Sep 14; Vol. 22 (1), pp. 33. Date of Electronic Publication: 2021 Sep 14.