N-cadherin-mediated interaction with multiple myeloma cells inhibits osteoblast differentiation

Autor: Richard W.J. Groen, Martin F.M. de Rooij, Kinga A. Kocemba, Rogier M. Reijmers, Anneke de Haan-Kramer, Marije B. Overdijk, Linda Aalders, Henk Rozemuller, Anton C.M. Martens, P. Leif Bergsagel, Marie José Kersten, Steven T. Pals, Marcel Spaargaren

Publikováno v: Haematologica, Vol 96, Iss 11 (2011)

Background Multiple myeloma is a hematologic malignancy characterized by a clonal expansion of malignant plasma cells in the bone marrow, which is accompanied by the development of osteolytic lesions and/or diffuse osteopenia. The intricate bi-direct

Externí odkaz: https://doaj.org/article/4eb6c435303b45fba49c3954e4209c32

The hypoxia target adrenomedullin is aberrantly expressed in multiple myeloma and promotes angiogenesis

Autor: H van Andel, Marcel Spaargaren, Marie-Jose Kersten, Kinga A. Kocemba, Steven T. Pals, Karène Mahtouk, Rogier Versteeg, A de Haan-Kramer

Publikováno v: Leukemia, 27(8), 1729-1737. Nature Publishing Group

In multiple myeloma (MM), angiogenesis is strongly correlated to disease progression and unfavorable outcome, and may be promoted by bone marrow hypoxia. Employing gene-expression profiling, we here identified the pro-angiogenic factor adrenomedullin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf5c0875bb4999429c72647eadd2516e
https://doi.org/10.1038/leu.2013.76

N-cadherin-mediated interaction with multiple myeloma cells inhibits osteoblast differentiation

Autor: P. Leif Bergsagel, Kinga A. Kocemba, Martin F. M. de Rooij, Anton C.M. Martens, Marcel Spaargaren, Anneke de Haan-Kramer, Richard W.J. Groen, Marie José Kersten, Steven T. Pals, Henk Rozemuller, Marije B. Overdijk, Rogier M. Reijmers, Linda Aalders

Publikováno v: Haematologica, 96(11), 1653-1661. Ferrata Storti Foundation
Haematologica, 96(11), 1653-61. Ferrata Storti Foundation
Haematologica, 96(11), 1653. Ferrata Storti Foundation
Groen, R W J, de Rooij, M F M, Kocemba, K A, Reijmers, R M, de Haan-Kramer, A, Overdijk, M B, Aalders, L, Rozemuller, H, Martens, A C M, Bergsagel, P L, Kersten, M J, Pals, S T & Spaargaren, M 2011, ' N-cadherin-mediated interaction with multiple myeloma cells inhibits osteoblast differentiation ', Haematologica, vol. 96, no. 11, pp. 1653-61 . https://doi.org/10.3324/haematol.2010.038133

BACKGROUND: Multiple myeloma is a hematologic malignancy characterized by a clonal expansion of malignant plasma cells in the bone marrow, which is accompanied by the development of osteolytic lesions and/or diffuse osteopenia. The intricate bi-direc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::733fd87c94636c7076444e62eaa471ba
https://dare.uva.nl/personal/pure/en/publications/ncadherinmediated-interaction-with-multiple-myeloma-cells-inhibits-osteoblast-differentiation(7a94f0dc-cd04-4ebc-910d-c9146278fe71).html

Targeting EXT1 reveals a crucial role for heparan sulfate in the growth of multiple myeloma

Autor: Reijmers, Rogier M. ^*, Groen, Richard W.J. ^*, Rozemuller, Henk, Kuil, Annemieke, de Haan-Kramer, Anneke, Csikós, Tamás, Martens, Anton C.M., Spaargaren, Marcel, Pals, Steven T. ^*

Publikováno v: In Blood 21 January 2010 115(3):601-604

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.