Cell fate determination by Lamarckian molecule-inheritance and chance

Autor: Schouten J, Frank J. Bruggeman, Robert Planqué, de Groot Dh

Single, isogenic cells can differ in their survival and adaptation capacity. This phenotypic diversity is generally due to stochastic molecular events. Since mother cells on average pass half of their molecular content on to their daughters, the stat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6ea74893cb7de4d89aa1ba93dd108ca

Effective bet-hedging through growth rate dependent stability.

Autor: de Groot DH; Biozentrum and Swiss Institute of Bioinformatics, University of Basel, Basel 4056, Switzerland.; Systems Biology Lab, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit, Amsterdam 1081HZ, The Netherlands., Tjalma AJ; Systems Biology Lab, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit, Amsterdam 1081HZ, The Netherlands.; Institute for Atomic and Molecular Physics, Amsterdam 1098XG, The Netherlands., Bruggeman FJ; Systems Biology Lab, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit, Amsterdam 1081HZ, The Netherlands., van Nimwegen E; Biozentrum and Swiss Institute of Bioinformatics, University of Basel, Basel 4056, Switzerland.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Feb 21; Vol. 120 (8), pp. e2211091120. Date of Electronic Publication: 2023 Feb 13.

Metabolic control of nitrogen fixation in rhizobium-legume symbioses.

Autor: Schulte CCM; Department of Plant Sciences, University of Oxford, Oxford, UK.; Department of Engineering Science, University of Oxford, Oxford, UK., Borah K; Department of Plant Sciences, University of Oxford, Oxford, UK., Wheatley RM; Department of Plant Sciences, University of Oxford, Oxford, UK., Terpolilli JJ; John Innes Centre, Norwich Research Park, Norwich, UK., Saalbach G; John Innes Centre, Norwich Research Park, Norwich, UK., Crang N; Department of Plant Sciences, University of Oxford, Oxford, UK., de Groot DH; Systems Biology Lab, AIMMS, Vrije Universiteit Amsterdam, Amsterdam, Netherlands., Ratcliffe RG; Department of Plant Sciences, University of Oxford, Oxford, UK. george.ratcliffe@plants.ox.ac.uk nick.kruger@plants.ox.ac.uk antonis@eng.ox.ac.uk philip.poole@plants.ox.ac.uk., Kruger NJ; Department of Plant Sciences, University of Oxford, Oxford, UK. george.ratcliffe@plants.ox.ac.uk nick.kruger@plants.ox.ac.uk antonis@eng.ox.ac.uk philip.poole@plants.ox.ac.uk., Papachristodoulou A; Department of Engineering Science, University of Oxford, Oxford, UK. george.ratcliffe@plants.ox.ac.uk nick.kruger@plants.ox.ac.uk antonis@eng.ox.ac.uk philip.poole@plants.ox.ac.uk., Poole PS; Department of Plant Sciences, University of Oxford, Oxford, UK. george.ratcliffe@plants.ox.ac.uk nick.kruger@plants.ox.ac.uk antonis@eng.ox.ac.uk philip.poole@plants.ox.ac.uk.; John Innes Centre, Norwich Research Park, Norwich, UK.

Publikováno v: Science advances [Sci Adv] 2021 Jul 30; Vol. 7 (31). Date of Electronic Publication: 2021 Jul 30 (Print Publication: 2021).

Unlocking Elementary Conversion Modes: ecmtool Unveils All Capabilities of Metabolic Networks.

Autor: Clement TJ; Systems Biology Lab, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1087, 1081 HV Amsterdam, the Netherlands., Baalhuis EB; Department of Mathematics, Vrije Universiteit Amsterdam, De Boelelaan 1081a, 1081 HV Amsterdam, the Netherlands., Teusink B; Systems Biology Lab, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1087, 1081 HV Amsterdam, the Netherlands., Bruggeman FJ; Systems Biology Lab, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1087, 1081 HV Amsterdam, the Netherlands., Planqué R; Systems Biology Lab, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1087, 1081 HV Amsterdam, the Netherlands.; Department of Mathematics, Vrije Universiteit Amsterdam, De Boelelaan 1081a, 1081 HV Amsterdam, the Netherlands., de Groot DH; Systems Biology Lab, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1087, 1081 HV Amsterdam, the Netherlands.

Publikováno v: Patterns (New York, N.Y.) [Patterns (N Y)] 2020 Dec 29; Vol. 2 (1), pp. 100177. Date of Electronic Publication: 2020 Dec 29 (Print Publication: 2021).

Elementary Growth Modes provide a molecular description of cellular self-fabrication.

Autor: de Groot DH; Systems Bioinformatics, Amsterdam Institute for Molecules, Medicines & Systems, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Hulshof J; Department of Mathematics, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Teusink B; Systems Bioinformatics, Amsterdam Institute for Molecules, Medicines & Systems, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Bruggeman FJ; Systems Bioinformatics, Amsterdam Institute for Molecules, Medicines & Systems, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Planqué R; Systems Bioinformatics, Amsterdam Institute for Molecules, Medicines & Systems, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Department of Mathematics, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

Publikováno v: PLoS computational biology [PLoS Comput Biol] 2020 Jan 27; Vol. 16 (1), pp. e1007559. Date of Electronic Publication: 2020 Jan 27 (Print Publication: 2020).