Zobrazeno 1 - 10
of 119
pro vyhledávání: '"de Esch IJ"'
Autor:
Bosma R; Amsterdam Institute for Molecules, Medicines and Systems, Division of Medicinal Chemistry, Faculty of Science , VU University Amsterdam , De Boelelaan 1083 , 1081 HV Amsterdam , The Netherlands., Wang Z; Amsterdam Institute for Molecules, Medicines and Systems, Division of Medicinal Chemistry, Faculty of Science , VU University Amsterdam , De Boelelaan 1083 , 1081 HV Amsterdam , The Netherlands., Kooistra AJ; Amsterdam Institute for Molecules, Medicines and Systems, Division of Medicinal Chemistry, Faculty of Science , VU University Amsterdam , De Boelelaan 1083 , 1081 HV Amsterdam , The Netherlands., Bushby N; Operations, BioPharmaceuticals R&D , AstraZeneca , Alderley Park , Macclesfield SK10 4TG , United Kingdom., Kuhne S; Amsterdam Institute for Molecules, Medicines and Systems, Division of Medicinal Chemistry, Faculty of Science , VU University Amsterdam , De Boelelaan 1083 , 1081 HV Amsterdam , The Netherlands., van den Bor J; Amsterdam Institute for Molecules, Medicines and Systems, Division of Medicinal Chemistry, Faculty of Science , VU University Amsterdam , De Boelelaan 1083 , 1081 HV Amsterdam , The Netherlands., Waring MJ; Medicinal Chemistry, Research and Early Development, Oncology R&D , AstraZeneca , Alderley Park , Macclesfield SK10 4TG , United Kingdom., de Graaf C; Amsterdam Institute for Molecules, Medicines and Systems, Division of Medicinal Chemistry, Faculty of Science , VU University Amsterdam , De Boelelaan 1083 , 1081 HV Amsterdam , The Netherlands., de Esch IJ; Amsterdam Institute for Molecules, Medicines and Systems, Division of Medicinal Chemistry, Faculty of Science , VU University Amsterdam , De Boelelaan 1083 , 1081 HV Amsterdam , The Netherlands., Vischer HF; Amsterdam Institute for Molecules, Medicines and Systems, Division of Medicinal Chemistry, Faculty of Science , VU University Amsterdam , De Boelelaan 1083 , 1081 HV Amsterdam , The Netherlands., Sheppard RJ; Medicinal Chemistry, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D , AstraZeneca , Gothenburg 431 50 , Sweden., Wijtmans M; Amsterdam Institute for Molecules, Medicines and Systems, Division of Medicinal Chemistry, Faculty of Science , VU University Amsterdam , De Boelelaan 1083 , 1081 HV Amsterdam , The Netherlands., Leurs R; Amsterdam Institute for Molecules, Medicines and Systems, Division of Medicinal Chemistry, Faculty of Science , VU University Amsterdam , De Boelelaan 1083 , 1081 HV Amsterdam , The Netherlands.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2019 Jul 25; Vol. 62 (14), pp. 6630-6644. Date of Electronic Publication: 2019 Jul 05.
Autor:
McGuire R; Centre for Molecular and Biomolecular Informatics (CMBI), Radboudumc , 6525 GA Nijmegen, The Netherlands.; BioAxis Research , Pivot Park, 5349 AE Oss, The Netherlands., Verhoeven S; Netherlands eScience Center , 1098 XG Amsterdam, The Netherlands., Vass M; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Vrije Universiteit Amsterdam , 1081 HZ Amsterdam, The Netherlands., Vriend G; Centre for Molecular and Biomolecular Informatics (CMBI), Radboudumc , 6525 GA Nijmegen, The Netherlands., de Esch IJ; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Vrije Universiteit Amsterdam , 1081 HZ Amsterdam, The Netherlands., Lusher SJ; Centre for Molecular and Biomolecular Informatics (CMBI), Radboudumc , 6525 GA Nijmegen, The Netherlands.; Netherlands eScience Center , 1098 XG Amsterdam, The Netherlands., Leurs R; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Vrije Universiteit Amsterdam , 1081 HZ Amsterdam, The Netherlands., Ridder L; Netherlands eScience Center , 1098 XG Amsterdam, The Netherlands., Kooistra AJ; Centre for Molecular and Biomolecular Informatics (CMBI), Radboudumc , 6525 GA Nijmegen, The Netherlands.; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Vrije Universiteit Amsterdam , 1081 HZ Amsterdam, The Netherlands., Ritschel T; Centre for Molecular and Biomolecular Informatics (CMBI), Radboudumc , 6525 GA Nijmegen, The Netherlands., de Graaf C; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Vrije Universiteit Amsterdam , 1081 HZ Amsterdam, The Netherlands.
Publikováno v:
Journal of chemical information and modeling [J Chem Inf Model] 2017 Feb 27; Vol. 57 (2), pp. 115-121. Date of Electronic Publication: 2017 Feb 14.
Autor:
Kuhne S; Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam , De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands., Kooistra AJ; Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam , De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands., Bosma R; Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam , De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands., Bortolato A; Heptares Therapeutics Ltd. , BioPark, Broadwater Road, Welwyn Garden City, Herts AL7 3AX, U.K., Wijtmans M; Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam , De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands., Vischer HF; Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam , De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands., Mason JS; Heptares Therapeutics Ltd. , BioPark, Broadwater Road, Welwyn Garden City, Herts AL7 3AX, U.K., de Graaf C; Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam , De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands., de Esch IJ; Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam , De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands., Leurs R; Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam , De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2016 Oct 13; Vol. 59 (19), pp. 9047-9061. Date of Electronic Publication: 2016 Sep 27.
Autor:
Vass M; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands., Kooistra AJ; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands; Centre for Molecular and Biomolecular Informatics (CMBI), Radboud University Medical Center, Geert Grooteplein-Zuid 26-28, 6525 GA Nijmegen, The Netherlands., Ritschel T; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands; Centre for Molecular and Biomolecular Informatics (CMBI), Radboud University Medical Center, Geert Grooteplein-Zuid 26-28, 6525 GA Nijmegen, The Netherlands., Leurs R; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands., de Esch IJ; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands., de Graaf C; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands. Electronic address: c.de.graaf@vu.nl.
Publikováno v:
Current opinion in pharmacology [Curr Opin Pharmacol] 2016 Oct; Vol. 30, pp. 59-68. Date of Electronic Publication: 2016 Jul 29.
Autor:
Jansen C; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute of Molecules, Medicines and Systems (AIMMS), Vrije Universiteit Amsterdam , De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands., Kooistra AJ; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute of Molecules, Medicines and Systems (AIMMS), Vrije Universiteit Amsterdam , De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands., Kanev GK; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute of Molecules, Medicines and Systems (AIMMS), Vrije Universiteit Amsterdam , De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands., Leurs R; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute of Molecules, Medicines and Systems (AIMMS), Vrije Universiteit Amsterdam , De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands., de Esch IJ; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute of Molecules, Medicines and Systems (AIMMS), Vrije Universiteit Amsterdam , De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands., de Graaf C; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute of Molecules, Medicines and Systems (AIMMS), Vrije Universiteit Amsterdam , De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2016 Aug 11; Vol. 59 (15), pp. 7029-65. Date of Electronic Publication: 2016 Mar 18.
Autor:
Kooistra AJ; Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands., Vischer HF; Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands., McNaught-Flores D; Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands., Leurs R; Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands., de Esch IJ; Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands., de Graaf C; Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Division of Medicinal Chemistry, Faculty of Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands.
Publikováno v:
Scientific reports [Sci Rep] 2016 Jun 24; Vol. 6, pp. 28288. Date of Electronic Publication: 2016 Jun 24.
Autor:
Siderius M; Amsterdam Institute of Molecules, Medicines and Systems (AIMMS), Division of Medicinal Chemistry, VU University Amsterdam, De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands. Electronic address: m.siderius@vu.nl., Shanmugham A; IOTA Pharmaceuticals, St. John's Innovation Centre, Cowley Road, Cambridge CB4 0WS, United Kingdom., England P; IOTA Pharmaceuticals, St. John's Innovation Centre, Cowley Road, Cambridge CB4 0WS, United Kingdom., van der Meer T; Amsterdam Institute of Molecules, Medicines and Systems (AIMMS), Division of Medicinal Chemistry, VU University Amsterdam, De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands., Bebelman JP; Amsterdam Institute of Molecules, Medicines and Systems (AIMMS), Division of Medicinal Chemistry, VU University Amsterdam, De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands., Blaazer AR; Amsterdam Institute of Molecules, Medicines and Systems (AIMMS), Division of Medicinal Chemistry, VU University Amsterdam, De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands., de Esch IJ; Amsterdam Institute of Molecules, Medicines and Systems (AIMMS), Division of Medicinal Chemistry, VU University Amsterdam, De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands; IOTA Pharmaceuticals, St. John's Innovation Centre, Cowley Road, Cambridge CB4 0WS, United Kingdom., Leurs R; Amsterdam Institute of Molecules, Medicines and Systems (AIMMS), Division of Medicinal Chemistry, VU University Amsterdam, De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands; IOTA Pharmaceuticals, St. John's Innovation Centre, Cowley Road, Cambridge CB4 0WS, United Kingdom.
Publikováno v:
Analytical biochemistry [Anal Biochem] 2016 Jun 15; Vol. 503, pp. 41-9. Date of Electronic Publication: 2016 Mar 28.
Autor:
Kooistra AJ; Division of Medicinal Chemistry, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Vrije Universiteit Amsterdam, Amsterdam, 1081 HV, The Netherlands., Kanev GK; Division of Medicinal Chemistry, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Vrije Universiteit Amsterdam, Amsterdam, 1081 HV, The Netherlands., van Linden OP; Division of Medicinal Chemistry, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Vrije Universiteit Amsterdam, Amsterdam, 1081 HV, The Netherlands., Leurs R; Division of Medicinal Chemistry, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Vrije Universiteit Amsterdam, Amsterdam, 1081 HV, The Netherlands., de Esch IJ; Division of Medicinal Chemistry, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Vrije Universiteit Amsterdam, Amsterdam, 1081 HV, The Netherlands., de Graaf C; Division of Medicinal Chemistry, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Vrije Universiteit Amsterdam, Amsterdam, 1081 HV, The Netherlands c.de.graaf@vu.nl.
Publikováno v:
Nucleic acids research [Nucleic Acids Res] 2016 Jan 04; Vol. 44 (D1), pp. D365-71. Date of Electronic Publication: 2015 Oct 22.
Autor:
Ruepp MD; Department of Chemistry and Biochemistry, University of Bern, Freiestrasse 3, CH-3012 Bern, Switzerland., Brozik JA; Washington State University, Department of Chemistry, Pullman, WA 99164-4630, USA., de Esch IJ; Medicinal Chemistry, VU University Amsterdam, Amsterdam, The Netherlands., Farndale RW; Department of Biochemistry, University of Cambridge, Cambridge CB2 1QW, UK., Murrell-Lagnado RD; Department of Pharmacology, Tennis Court Road, Cambridge CB2 1PD, UK., Thompson AJ; Department of Pharmacology, Tennis Court Road, Cambridge CB2 1PD, UK. Electronic address: ajt44@cam.ac.uk.
Publikováno v:
Neuropharmacology [Neuropharmacology] 2015 Nov; Vol. 98, pp. 13-21. Date of Electronic Publication: 2015 May 28.
Autor:
Hameetman L; Department of Dermatology, Leiden University Medical Center, Leiden, The Netherlands., van der Fits L; Department of Dermatology, Leiden University Medical Center, Leiden, The Netherlands., Zoutman WH; Department of Dermatology, Leiden University Medical Center, Leiden, The Netherlands., Out-Luiting JJ; Department of Dermatology, Leiden University Medical Center, Leiden, The Netherlands., Siegal G; Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands., de Esch IJ; Leiden/Amsterdam Center for Drug Research (LACDR), Division of Medicinal Chemistry, Faculty of Sciences, VU University Amsterdam, Amsterdam, The Netherlands., Vermeer MH; Department of Dermatology, Leiden University Medical Center, Leiden, The Netherlands., Tensen CP; Department of Dermatology, Leiden University Medical Center, Leiden, The Netherlands.
Publikováno v:
Oncotarget [Oncotarget] 2015 Oct 13; Vol. 6 (31), pp. 31868-76.