Zobrazeno 1 - 10 of 62 pro vyhledávání: '"de Dick Zeeuw"'
1
Renal outcomes with aliskiren in patients with type 2 diabetes
Autor: John J.V. McMurray, Hans-Henrik Parving, Patrick Brunel, Frederik Persson, Hiddo J.L. Heerspink, Akshay S. Desai, Marc A. Pfeffer, Scott D. Solomon, Nish Chaturvedi, Barry M. Brenner, de Dick Zeeuw
Publikováno v: Lancet Diabetes & Endocrinology, 4(4), 309-317. ELSEVIER SCIENCE INC
BACKGROUND: The primary results of the ALTITUDE trial showed no benefit of aliskiren on renal outcomes (doubling of serum creatinine and end-stage renal disease) when used as an adjunct to angiotensin-converting enzyme (ACE) inhibitors or angiotensin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51c36b5fcbd4f1e4ced532975aadd181
https://doi.org/10.1016/s2213-8587(15)00469-6
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2
Novel anti-inflammatory drugs for the treatment of diabetic kidney disease
Autor: Hiddo J.L. Heerspink, de Dick Zeeuw
Publikováno v: Diabetologia, 59(8), 1621-1623. SPRINGER
Over the last decade, numerous studies have demonstrated that inflammation is involved in the cascade of events that lead to renal complications in patients with diabetic kidney disease [1]. Experimental studies highlighted the pathogenic role of inf
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7692f6751d0ae1d0eed75229006da20b
https://doi.org/10.1007/s00125-016-4030-4
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4
Determining the Optimal Protocol for Measuring an Albuminuria Class Transition in Clinical Trials in Diabetic Kidney Disease
Autor: Hans-Henrik Parving, Rudy Bilous, Hiddo J.L. Heerspink, Tobias F. Kröpelin, Giuseppe Remuzzi, de Dick Zeeuw
Publikováno v: Journal of the American Society of Nephrology, 27(11), 3405-3412. AMER SOC NEPHROLOGY
Albuminuria class transition (normo-to micro-to macroalbuminuria) is used as an intermediate end point to assess renoprotective drug efficacy. However, definitions of such class transition vary between trials. To determine the most optimal protocol,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84263e9cb16fc2482d9ade4d3eb6833a
https://europepmc.org/articles/PMC5084894/
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5
Renal failure induces telomere shortening in the rat heart
Autor: de Dick Zeeuw, Regina Schoemaker, Ajm Roks, Robert H. Henning, R. P. van Dokkum, L. S. Wong, Willemijn A.K.M. Windt
Publikováno v: Netherlands Heart Journal. 17:190-194
BackgroundRenal failure aggravates pathological cardiac remodelling induced by myocardial infarction (MI). Cardiac remodelling is associated with telomere shortening, a marker for biological ageing. We investigated whether mild and severe renal failu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49870f9c84998ba6c9d46b3aed5b66e2
https://doi.org/10.1007/bf03086245
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6
Selective cyclooxygenase-2 (COX-2) inhibition reduces proteinuria in renal patients
Autor: de Dick Zeeuw, Gerarda Navis, Liffert Vogt, Arend Jan J. Woittiez
Publikováno v: Nephrology, dialysis, transplantation, 24(4), 1182-1189. Oxford University Press
Nephrology Dialysis Transplantation, 24(4), 1182-1189. Oxford University Press
Background. Renoprotection is predicted by the antiproteinuric efficacy of a pharmacological agent. Nonsteroidal anti-inflammatory drugs (NSAIDs) interfering non-selectively in the prostaglandin system have strong antiproteinuric potency without redu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11b666d6315ad7605603de047f41724f
https://doi.org/10.1093/ndt/gfn644
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7
Systemic gene therapy with interleukin-13 attenuates renal ischemia–reperfusion injury
Autor: Wijnand Helfrich, van Harry Goor, Robert H. Henning, Maria Sandovici, de Dick Zeeuw, Leo E. Deelman
Publikováno v: Kidney International, 73(12), 1364-1373. ELSEVIER SCIENCE INC
Ischemia-reperfusion injury is a leading cause of acute renal failure and a major determinant in the outcome of kidney transplantation. Here we explored systemic gene therapy with a modified adenovirus expressing Interleukin (IL)-13, a cytokine with
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15440c07a7df27d673f8a81eefde29f9
https://doi.org/10.1038/ki.2008.18
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8
Unilateral Kidney Blood Flow Measurement Using the 81Rb/8lmKr Ratio
Autor: G. van Herk, de Dick Zeeuw
A new method has been developed for the continuous quantification of kidney blood flow, utilizing the unique physical and biological properties of the radioactive tracer couple: rubidium-81/krypton-81m. After intravenous injection, 81Rb concentrates
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::91dbfe9d1642fdbe69b6dfa3c8908a88
https://doi.org/10.1159/000401779
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