The calculated genetic barrier for antiretroviral drug resistance substitutions is largely similar for different HIV-1 subtypes

Autor: van de Vijver, DA Wensing, AMJ Angarano, G Asjo, B and Balotta, C Boeri, E Camacho, R Chaix, ML Costagliola, D and De Luca, A Derdelinckx, I Grossman, Z Hamouda, O and Hatzakis, A Hemmer, R Hoepelman, A Horban, A Korn, K and Kucherer, C Leitner, T Loveday, C MacRae, E Maljkovic, I and de Mendoza, C Meyer, L Nielsen, C de Coul, ELMO and Ormaasen, V Paraskevis, D Perrin, L Puchhammer-Stockl, E and Ruiz, L Salminen, M Schmit, JC Schneider, F Schuurman, R and Soriano, V Stanczak, G Stanojevic, M Vandamme, AM and Van Laethem, K Violin, M Wilbe, K Yerly, S Zazzi, M and Boucher, CAB SPREAD Programme

Background: The genetic barrier, defined as the number of mutations required to overcome drug-selective pressure, is an important factor for the development of HIV drug resistance. Because of high variability between subtypes, particular HIV-1 subtyp

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https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3098985

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Substantial impact of the COVID-19 pandemic on the reported number of diagnosed chronic hepatitis C virus infections in the Netherlands, 2019-2021.

Autor: den Boogert EM; Centre for Infectious Disease Control, Epidemiology and Surveillance, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands. e.den.boogert@ggdhvb.nl.; ECDC Fellowship Programme, Field Epidemiology Path (EPIET), European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden. e.den.boogert@ggdhvb.nl., Veldhuijzen IK; Centre for Infectious Disease Control, Epidemiology and Surveillance, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands., Generaal E; Department of Infectious Diseases, Research and Prevention, Public Health Service of Amsterdam, Amsterdam, the Netherlands., Prins M; Department of Infectious Diseases, Research and Prevention, Public Health Service of Amsterdam, Amsterdam, the Netherlands.; Department of Infectious Diseases, Amsterdam UMC, Amsterdam Infection and Immunity (AII), University of Amsterdam, Amsterdam, the Netherlands., Sonneveld MJ; Department of Gastroenterology & Hepatology, Erasmus MC University Medical Center, Rotterdam, the Netherlands., van der Meer AJ; Department of Gastroenterology & Hepatology, Erasmus MC University Medical Center, Rotterdam, the Netherlands., Zantkuijl P; Soa Aids Nederland, Amsterdam, the Netherlands., van Benthem BHB; Centre for Infectious Disease Control, Epidemiology and Surveillance, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands., de Coul ELMO; Centre for Infectious Disease Control, Epidemiology and Surveillance, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.

Publikováno v: BMC public health [BMC Public Health] 2023 Jun 27; Vol. 23 (1), pp. 1244. Date of Electronic Publication: 2023 Jun 27.