Radiosynthesis of ( E)- N-(2-[ 11C]methoxybenzyl)-3-phenyl-acrylamidine, a novel subnanomolar NR2B subtype-selective NMDA receptor antagonist

Autor: Thominiaux, Cyrille, de Bruin, Béatrice, Bramoullé, Yann, Hinnen, Françoise, Demphel, Stéphane, Valette, Heric, Bottlaender, Michel, Besret, Laurent, Kassiou, Michael, Dollé, Frédéric

Publikováno v: In Applied Radiation and Isotopes 2006 64(3):348-354

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The use of biocatalysis in the synthesis of labelled compounds.

Autor: Allen, John, Brasseur, Denis M., De Bruin, Béatrice, Denoux, Mireille, Pérard, Serge, Philippe, Nicolas, Roy, Sébastien N.

Publikováno v: Journal of Labelled Compounds & Radiopharmaceuticals; Apr2007, Vol. 50 Issue 5/6, p342-346, 5p

Evaluation of drug penetration into the brain: a double study by in vivo imaging with positron emission tomography and using an in vitro model of the human blood-brain barrier.

Autor: Josserand, Véronique, Pélerin, Hélène, de Bruin, Béatrice, Jego, Benoît, Kuhnast, Bertrand, Hinnen, Françoise, Ducongé, Frédéric, Boisgard, Raphaël, Beuvon, Frédéric, Chassoux, Francine, Daumas-Duport, Catherine, Ezan, Eric, Dollé, Frédéric, Mabondzo, Aloïse, Tavitian, Bertrand

Publikováno v: The Journal of Pharmacology and Experimental Therapeutics; January 2006, Vol. 316 Issue: 1 p79-86, 8p

1-[3-(2-[18F]fluoropyridin-3-yloxy)propyl]pyrrole-2,5-dione: design, synthesis, and radiosynthesis of a new [18F]fluoropyridine-based maleimide reagent for the labeling of peptides and proteins.

Autor: de Bruin B; Service Hospitalier Frédéric Joliot, Département de Recherche Médicale, CEA/DSV, 4 place du Général Leclerc, F-91401 Orsay, France., Kuhnast B, Hinnen F, Yaouancq L, Amessou M, Johannes L, Samson A, Boisgard R, Tavitian B, Dollé F

Publikováno v: Bioconjugate chemistry [Bioconjug Chem] 2005 Mar-Apr; Vol. 16 (2), pp. 406-20.