A transcriptomic and epigenomic cell atlas of the mouse primary motor cortex.

Autor: Yao Z; Allen Institute for Brain Science, Seattle, WA, USA., Liu H; Genomic Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA., Xie F; Department of Physics, University of California, San Diego, La Jolla, CA, USA., Fischer S; Stanley Institute for Cognitive Genomics, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Adkins RS; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA., Aldridge AI; Genomic Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA., Ament SA; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA., Bartlett A; Genomic Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA., Behrens MM; Computational Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA., Van den Berge K; Department of Statistics, University of California, Berkeley, Berkeley, CA, USA.; Department of Applied Mathematics, Computer Science and Statistics, Ghent University, Gent, Belgium., Bertagnolli D; Allen Institute for Brain Science, Seattle, WA, USA., de Bézieux HR; Division of Biostatistics, School of Public Health, University of California, Berkeley, Berkeley, CA, USA., Biancalani T; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Booeshaghi AS; California Institute of Technology, Pasadena, CA, USA., Bravo HC; Center for Bioinformatics and Computational Biology, University of Maryland, College Park, College Park, MD, USA., Casper T; Allen Institute for Brain Science, Seattle, WA, USA., Colantuoni C; Johns Hopkins School of Medicine, Department of Neurology, Baltimore, MD, USA.; Johns Hopkins School of Medicine, Department of Neuroscience, Baltimore, MD, USA.; University of Maryland School of Medicine, Institute for Genome Sciences, Baltimore, MD, USA., Crabtree J; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA., Creasy H; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA., Crichton K; Allen Institute for Brain Science, Seattle, WA, USA., Crow M; Stanley Institute for Cognitive Genomics, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Dee N; Allen Institute for Brain Science, Seattle, WA, USA., Dougherty EL; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Doyle WI; Department of Cognitive Science, University of California, San Diego, La Jolla, CA, USA., Dudoit S; Department of Statistics, University of California, Berkeley, Berkeley, CA, USA., Fang R; Bioinformatics and Systems Biology Graduate Program, University of California, San Diego, San Diego, CA, USA., Felix V; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA., Fong O; Allen Institute for Brain Science, Seattle, WA, USA., Giglio M; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA., Goldy J; Allen Institute for Brain Science, Seattle, WA, USA., Hawrylycz M; Allen Institute for Brain Science, Seattle, WA, USA., Herb BR; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA., Hertzano R; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Otorhinolaryngology, Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD, USA., Hou X; Center for Epigenomics, Department of Cellular and Molecular Medicine, University of California, San Diego School of Medicine, La Jolla, CA, USA., Hu Q; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA., Kancherla J; Center for Bioinformatics and Computational Biology, University of Maryland, College Park, College Park, MD, USA., Kroll M; Allen Institute for Brain Science, Seattle, WA, USA., Lathia K; Allen Institute for Brain Science, Seattle, WA, USA., Li YE; Ludwig Institute for Cancer Research, La Jolla, CA, USA., Lucero JD; Computational Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA., Luo C; Genomic Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA.; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA.; Howard Hughes Medical Institute, The Salk Institute for Biological Studies, La Jolla, CA, USA., Mahurkar A; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA., McMillen D; Allen Institute for Brain Science, Seattle, WA, USA., Nadaf NM; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Nery JR; Genomic Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA., Nguyen TN; Allen Institute for Brain Science, Seattle, WA, USA., Niu SY; Genomic Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA., Ntranos V; University of California, San Francisco, San Francisco, CA, USA., Orvis J; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA., Osteen JK; Computational Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA., Pham T; Allen Institute for Brain Science, Seattle, WA, USA., Pinto-Duarte A; Computational Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA., Poirion O; Center for Epigenomics, Department of Cellular and Molecular Medicine, University of California, San Diego School of Medicine, La Jolla, CA, USA., Preissl S; Center for Epigenomics, Department of Cellular and Molecular Medicine, University of California, San Diego School of Medicine, La Jolla, CA, USA., Purdom E; Department of Statistics, University of California, Berkeley, Berkeley, CA, USA., Rimorin C; Allen Institute for Brain Science, Seattle, WA, USA., Risso D; Department of Statistical Sciences, University of Padova, Padova, Italy., Rivkin AC; Howard Hughes Medical Institute, The Salk Institute for Biological Studies, La Jolla, CA, USA., Smith K; Allen Institute for Brain Science, Seattle, WA, USA., Street K; Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA, USA., Sulc J; Allen Institute for Brain Science, Seattle, WA, USA., Svensson V; California Institute of Technology, Pasadena, CA, USA., Tieu M; Allen Institute for Brain Science, Seattle, WA, USA., Torkelson A; Allen Institute for Brain Science, Seattle, WA, USA., Tung H; Allen Institute for Brain Science, Seattle, WA, USA., Vaishnav ED; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Vanderburg CR; Broad Institute of MIT and Harvard, Cambridge, MA, USA., van Velthoven C; Allen Institute for Brain Science, Seattle, WA, USA., Wang X; Center for Epigenomics, Department of Cellular and Molecular Medicine, University of California, San Diego School of Medicine, La Jolla, CA, USA.; McDonnell Genome Institute, Washington University School of Medicine, St Louis, MO, USA., White OR; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA., Huang ZJ; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Kharchenko PV; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA., Pachter L; California Institute of Technology, Pasadena, CA, USA., Ngai J; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA., Regev A; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Howard Hughes Medical Institute, Department of Biology, MIT, Cambridge, MA, USA., Tasic B; Allen Institute for Brain Science, Seattle, WA, USA., Welch JD; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA., Gillis J; Stanley Institute for Cognitive Genomics, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Macosko EZ; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Ren B; Center for Epigenomics, Department of Cellular and Molecular Medicine, University of California, San Diego School of Medicine, La Jolla, CA, USA.; Ludwig Institute for Cancer Research, La Jolla, CA, USA., Ecker JR; Genomic Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA.; Howard Hughes Medical Institute, The Salk Institute for Biological Studies, La Jolla, CA, USA., Zeng H; Allen Institute for Brain Science, Seattle, WA, USA. HongkuiZ@alleninstitute.org., Mukamel EA; Department of Cognitive Science, University of California, San Diego, La Jolla, CA, USA. emukamel@ucsd.edu.

Publikováno v: Nature [Nature] 2021 Oct; Vol. 598 (7879), pp. 103-110. Date of Electronic Publication: 2021 Oct 06.