Nebulized enriched heparin improves respiratory parameters in patients with COVID-19: a phase I/II randomized and triple-blind clinical trial.

Autor: Ramos da Silva Grillo VT; Department of Surgery and Orthopedics, Botucatu Medical School, São Paulo State University - UNESP, Clinical Hospital, Professor Montenegro Avenue, Botucatu, SP, 18618687, Brazil., Bertanha M; Department of Surgery and Orthopedics, Botucatu Medical School, São Paulo State University - UNESP, Clinical Hospital, Professor Montenegro Avenue, Botucatu, SP, 18618687, Brazil. matheusbertanha@gmail.com.; Applied Biotechnology Laboratory, Research Nucleus of Clinical Hospital, Botucatu Medical School, São Paulo State University - UNESP, Botucatu, SP, Brazil. matheusbertanha@gmail.com., da Silva Rodrigues L; Department of Surgery and Orthopedics, Botucatu Medical School, São Paulo State University - UNESP, Clinical Hospital, Professor Montenegro Avenue, Botucatu, SP, 18618687, Brazil.; Applied Biotechnology Laboratory, Research Nucleus of Clinical Hospital, Botucatu Medical School, São Paulo State University - UNESP, Botucatu, SP, Brazil., de Lima MA; Centre for Glycoscience, School of Life Sciences, Keele University, Newcastle-Under-Lyme, Staffordshire, UK., Mellucci Filho PL; Department of Surgery and Orthopedics, Botucatu Medical School, São Paulo State University - UNESP, Clinical Hospital, Professor Montenegro Avenue, Botucatu, SP, 18618687, Brazil., Rahal Guaragna Machado R; Department of Microbiology, Institute of Biomedical Sciences, University of Sao Paulo, - USP, São Paulo, Brazil., Durigon EL; Department of Microbiology, Institute of Biomedical Sciences, University of Sao Paulo, - USP, São Paulo, Brazil.; Scientific Platform Pasteur USP (SPPU), University of São Paulo, São Paulo, Brazil., Dias Sertorio N; Department of Surgery and Orthopedics, Botucatu Medical School, São Paulo State University - UNESP, Clinical Hospital, Professor Montenegro Avenue, Botucatu, SP, 18618687, Brazil., de Assis Golim M; Applied Biotechnology Laboratory, Research Nucleus of Clinical Hospital, Botucatu Medical School, São Paulo State University - UNESP, Botucatu, SP, Brazil., Moroz A; Department of Bioprocess and Biotechnology, School of Pharmaceutical Sciences, São Paulo State University - UNESP, Araraquara, SP, Brazil., Marques Braz AM; Applied Biotechnology Laboratory, Research Nucleus of Clinical Hospital, Botucatu Medical School, São Paulo State University - UNESP, Botucatu, SP, Brazil., de Moraes LN; Applied Biotechnology Laboratory, Research Nucleus of Clinical Hospital, Botucatu Medical School, São Paulo State University - UNESP, Botucatu, SP, Brazil., Leite MA; Clinical Hospital of the Botucatu Medical School, São Paulo State University - UNESP, Botucatu, SP, Brazil., Bonciani Nader H; Department of Biochemistry, Federal University of São Paulo - UNIFESP, São Paulo, SP, Brazil., de Campos GC; Department of Orthopedics and Traumatology, School of Medical Sciences, University of Campinas - UNICAMP, Campinas, SP, Brazil., Rodrigues Guzzo Carvalho C; Department of Microbiology, Institute of Biomedical Sciences, University of Sao Paulo, - USP, São Paulo, Brazil., Florença Cardoso F; Department of Biophysics and Pharmacology, Institute of Biosciences, São Paulo State University - UNESP, Botucatu, SP, Brazil., Magro AJ; Department of Biophysics and Pharmacology, Institute of Biosciences, São Paulo State University - UNESP, Botucatu, SP, Brazil., Caputo Nunes H; Teaching and Research Center of the Albert Einstein Hospital, São Paulo, SP, Brazil., Tommasini Grotto RM; Applied Biotechnology Laboratory, Research Nucleus of Clinical Hospital, Botucatu Medical School, São Paulo State University - UNESP, Botucatu, SP, Brazil.; Bioprocessing and Biotechnology Department, School of Agriculture, São Paulo State University - UNESP, Botucatu, SP, Brazil., de Cássia Alvarado R; Applied Biotechnology Laboratory, Research Nucleus of Clinical Hospital, Botucatu Medical School, São Paulo State University - UNESP, Botucatu, SP, Brazil., de Moura Campos Pardini MI; Internal Medicine Division, Botucatu Medical School, São Paulo State University - UNESP, Botucatu, SP, Brazil., Lima Sobreira M; Department of Surgery and Orthopedics, Botucatu Medical School, São Paulo State University - UNESP, Clinical Hospital, Professor Montenegro Avenue, Botucatu, SP, 18618687, Brazil., da Costa EAPN; Department of Infectious Diseases, Botucatu Medical School, São Paulo State University - UNESP, Botucatu, SP, Brazil., Naime Barbosa A; Department of Infectious Diseases, Botucatu Medical School, São Paulo State University - UNESP, Botucatu, SP, Brazil., Fortaleza CMCB; Department of Infectious Diseases, Botucatu Medical School, São Paulo State University - UNESP, Botucatu, SP, Brazil.

Publikováno v: Scientific reports [Sci Rep] 2024 Aug 27; Vol. 14 (1), pp. 19902. Date of Electronic Publication: 2024 Aug 27.

Cytotoxic Activity and Lymphocyte Subtypes in Mice Selected for Maximal and Minimal Inflammatory Response after Transplantation of B16F10 and S91 Melanoma Cells.

Autor: Castoldi L; Health Sciences Institute, Federal University of Mato Grosso-UFMT, Sinop, Mato Grosso, Brazil., Romagnoli GG; Department of Chemical and Biological Sciences, Institute of Bioscience of Botucatu, São Paulo State University-UNESP, Botucatu, São Paulo, Brazil.; Department Health Science, Oeste Paulista University-UNOESTE, Jaú, São Paulo, Brazil., de Assis Golim M; Hemocentro Division, School of Medicine of Botucatu, São Paulo State University-UNESP, Botucatu, São Paulo, Brazil., Ribeiro OG; Laboratory of Immunogenetics, Institute Butantan, São Paulo, São Paulo, Brazil., Martinez Ibañez OC; Laboratory of Immunogenetics, Institute Butantan, São Paulo, São Paulo, Brazil., Maria DA; Laboratory of Biochemistry and Biophysics, Institute Butantan, São Paulo, São Paulo, Brazil., Pinto Domeneghini AV; Central Paulista University Center - UNICEP, São Carlos, São Paulo, Brazil., Gameiro MC; Department of Chemical and Biological Sciences, Institute of Bioscience of Botucatu, São Paulo State University-UNESP, Botucatu, São Paulo, Brazil., Martins PR; Department of Chemical and Biological Sciences, Institute of Bioscience of Botucatu, São Paulo State University-UNESP, Botucatu, São Paulo, Brazil., Mischan MM; Department of Biostatistics, Institute of Bioscience of Botucatu, São Paulo State University-UNESP, Botucatu, São Paulo, Brazil., Kaneno R; Department of Chemical and Biological Sciences, Institute of Bioscience of Botucatu, São Paulo State University-UNESP, Botucatu, São Paulo, Brazil.

Publikováno v: International journal of inflammation [Int J Inflam] 2022 Feb 28; Vol. 2022, pp. 3298542. Date of Electronic Publication: 2022 Feb 28 (Print Publication: 2022).

Propolis increases Foxp3 expression and lymphocyte proliferation in HIV-infected people: A randomized, double blind, parallel-group and placebo-controlled study.

Autor: Conte FL; São Paulo State University (UNESP), Institute of Biosciences, Campus Botucatu, São Paulo, Brazil; São Paulo State University (UNESP), Botucatu Medical School, Campus Botucatu, São Paulo, Brazil., Tasca KI; São Paulo State University (UNESP), Institute of Biosciences, Campus Botucatu, São Paulo, Brazil., Santiago KB; São Paulo State University (UNESP), Institute of Biosciences, Campus Botucatu, São Paulo, Brazil., de Oliveira Cardoso E; São Paulo State University (UNESP), Institute of Biosciences, Campus Botucatu, São Paulo, Brazil., Romagnoli GG; São Paulo State University (UNESP), Institute of Biosciences, Campus Botucatu, São Paulo, Brazil., de Assis Golim M; São Paulo State University (UNESP), Botucatu Medical School, Campus Botucatu, São Paulo, Brazil., Braz AMM; São Paulo State University (UNESP), Botucatu Medical School, Campus Botucatu, São Paulo, Brazil., Berretta AA; Research, Development & Innovation Laboratory, Apis Flora Indl. Coml. Ltda., Ribeirão Preto, São Paulo, Brazil., do Rosário de Souza L; São Paulo State University (UNESP), Botucatu Medical School, Campus Botucatu, São Paulo, Brazil., Sforcin JM; São Paulo State University (UNESP), Institute of Biosciences, Campus Botucatu, São Paulo, Brazil. Electronic address: jose.m.sforcin@unesp.br.

Publikováno v: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 Oct; Vol. 142, pp. 111984. Date of Electronic Publication: 2021 Aug 05.

Transcriptional analysis of THP-1 cells infected with Leishmania infantum indicates no activation of the inflammasome platform.

Autor: Gatto M; Tropical Diseases Department, Botucatu Medical School - UNESP, Botucatu, Brazil., Borim PA; Tropical Diseases Department, Botucatu Medical School - UNESP, Botucatu, Brazil., Wolf IR; Bioprocess and Biotechnology Department, Agronomic Sciences School - UNESP, Botucatu, Brazil., Fukuta da Cruz T; Microbiology and Immunology Department, Biosciences Institute - UNESP, Botucatu, Brazil., Ferreira Mota GA; Internal Medicine Department, Botucatu Medical School - UNESP, Botucatu, Brazil., Marques Braz AM; Internal Medicine Department, Botucatu Medical School - UNESP, Botucatu, Brazil., Casella Amorim B; Tropical Diseases Department, Botucatu Medical School - UNESP, Botucatu, Brazil., Targino Valente G; Bioprocess and Biotechnology Department, Agronomic Sciences School - UNESP, Botucatu, Brazil., de Assis Golim M; Flow Cytometry Laboratory, Botucatu Medical School - UNESP, Botucatu, Brazil., Venturini J; Medical School - UFMS, Campo Grande, Brazil., Araújo Junior JP; Bioprocess and Biotechnology Department, Agronomic Sciences School - UNESP, Botucatu, Brazil., Pontillo A; Immunology Department, São Paulo University - USP, São Paulo, Brazil., Sartori A; Tropical Diseases Department, Botucatu Medical School - UNESP, Botucatu, Brazil.

Publikováno v: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2020 Jan 21; Vol. 14 (1), pp. e0007949. Date of Electronic Publication: 2020 Jan 21 (Print Publication: 2020).

Sonic hedgehog drives layered double hydroxides-induced acute inflammatory landscape.

Autor: da Silva Feltran G; Lab. de Bioensaios e Dinâmica Celular, Departamento de Química e Bioquímica, Instituto de Biociências, Universidade Estadual Paulista - UNESP, campus Botucatu, São Paulo, CEP 18618-970, Brazil., da Costa Fernandes CJ; Lab. de Bioensaios e Dinâmica Celular, Departamento de Química e Bioquímica, Instituto de Biociências, Universidade Estadual Paulista - UNESP, campus Botucatu, São Paulo, CEP 18618-970, Brazil., Rodrigues Ferreira M; Lab. de Bioensaios e Dinâmica Celular, Departamento de Química e Bioquímica, Instituto de Biociências, Universidade Estadual Paulista - UNESP, campus Botucatu, São Paulo, CEP 18618-970, Brazil., Kang HR; Lab. de Bioensaios e Dinâmica Celular, Departamento de Química e Bioquímica, Instituto de Biociências, Universidade Estadual Paulista - UNESP, campus Botucatu, São Paulo, CEP 18618-970, Brazil., de Carvalho Bovolato AL; Lab. de Engenharia Celular, Hemocentro, Hospital das Clínicas, Faculdade de Medicina de Botucatu, São Paulo, CEP 18618-688, Brazil., de Assis Golim M; Lab. de Engenharia Celular, Hemocentro, Hospital das Clínicas, Faculdade de Medicina de Botucatu, São Paulo, CEP 18618-688, Brazil., Deffune E; Lab. de Engenharia Celular, Hemocentro, Hospital das Clínicas, Faculdade de Medicina de Botucatu, São Paulo, CEP 18618-688, Brazil., Koh IHJ; Departamento de Cirurgia, Universidade Federal de São Paulo-UNIFESP, Rua Botucatu 740, CEP 04023-900, São Paulo, SP, Brazil., Constantino VRL; Departamento de Química Fundamental, Instituto de Química, Universidade de São Paulo-USP, Av. Prof. Lineu Prestes 748, CEP 05508-000, São Paulo, SP, Brazil., Zambuzzi WF; Lab. de Bioensaios e Dinâmica Celular, Departamento de Química e Bioquímica, Instituto de Biociências, Universidade Estadual Paulista - UNESP, campus Botucatu, São Paulo, CEP 18618-970, Brazil. Electronic address: w.zambuzzi@unesp.br.

Publikováno v: Colloids and surfaces. B, Biointerfaces [Colloids Surf B Biointerfaces] 2019 Feb 01; Vol. 174, pp. 467-475. Date of Electronic Publication: 2018 Nov 22.