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pro vyhledávání: '"ddc:61"'
Publikováno v:
Computational and Structural Biotechnology Journal. 21:780-795
Molecular interaction networks lay the foundation for studying how biological functions are controlled by the complex interplay of genes and proteins. Investigating perturbed processes using biological networks has been instrumental in uncovering mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::947acb9900c43710c8a632ef7b86fbf6
https://doi.org/10.1016/j.csbj.2022.12.022
https://doi.org/10.1016/j.csbj.2022.12.022
Autor:
Ledwig, Verena, Reichl, Stephan
The blood-brain barrier (BBB) is the bottleneck in the development of new drugs to reach the brain. Due to the BBB, toxic substances cannot enter the brain, but promising drug candidates also pass the BBB poorly. Suitable in vitro BBB models are ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______719::fed8243b6924cddabb453e0e0f30ed29
https://leopard.tu-braunschweig.de/servlets/MCRFileNodeServlet/dbbs_derivate_00051898/pharmaceutics-15-01688.pdf
https://leopard.tu-braunschweig.de/servlets/MCRFileNodeServlet/dbbs_derivate_00051898/pharmaceutics-15-01688.pdf
Publikováno v:
Separations; Volume 10; Issue 5; Pages: 320
Capillary zone electrophoresis (CZE) is an important technique for the analysis of monoclonal antibodies (mAbs). A recently released light-emitting diode (LED)-induced fluorescence (LEDIF) detector equipped with a 275 nm LED for the detection of prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6216936d20d2077161b8746bee10391b
https://leopard.tu-braunschweig.de/receive/dbbs_mods_00073370
https://leopard.tu-braunschweig.de/receive/dbbs_mods_00073370
Autor:
Demuth, Hendrik, Hosseini, Shirin, Düsedau, Henning Peter, Dunay, Ildikò Rita, Korte, Martin, Zagrebelsky, Marta
Publikováno v:
Frontiers in Molecular Neuroscience. 16
IntroductionAlzheimer’s disease (AD), is characterized by a gradual cognitive decline associated with the accumulation of Amyloid beta (Aβ)-oligomers, progressive neuronal degeneration and chronic neuroinflammation. Among the receptors shown to bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cbdce2580b33e988e993043573593f3
https://doi.org/10.3389/fnmol.2023.1163087
https://doi.org/10.3389/fnmol.2023.1163087
It is insightful to report an estimator that describes how certain a model is in a prediction, additionally to the prediction alone. For regression tasks, most approaches implement a variation of the ensemble method, apart from few exceptions. Instea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfc9fdccc240454be7512d6d6a2601d8
https://leopard.tu-braunschweig.de/servlets/MCRFileNodeServlet/dbbs_derivate_00051897/s13321-023-00709-9.pdf
https://leopard.tu-braunschweig.de/servlets/MCRFileNodeServlet/dbbs_derivate_00051897/s13321-023-00709-9.pdf
Autor:
Alessandro Dorigo, Komali Valishetti, Florian Hetsch, Hideaki Matsui, Jochen C. Meier, Kazuhiko Namikawa, Reinhard W. Köster
IntroductionThe cerebellum is organized into functional regions each dedicated to process different motor or sensory inputs for controlling different locomotor behaviors. This functional regionalization is prominent in the evolutionary conserved sing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35597503e49cf839c826b703de78830e
https://leopard.tu-braunschweig.de/servlets/MCRFileNodeServlet/dbbs_derivate_00051905/fnmol-16-1166900.pdf
https://leopard.tu-braunschweig.de/servlets/MCRFileNodeServlet/dbbs_derivate_00051905/fnmol-16-1166900.pdf
Autor:
Sol Pose-Méndez, Paul Schramm, Barbara Winter, Jochen C Meier, Konstantinos Ampatzis, Reinhard W Köster
Zebrafish have an impressive capacity to regenerate neurons in the central nervous system. However, regeneration of the principal neuron of the evolutionary conserved cerebellum, the Purkinje cell (PC), is believed to be limited to developmental stag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::178f2e8dc743bad20ad343443c976ef4
https://leopard.tu-braunschweig.de/receive/dbbs_mods_00073373
https://leopard.tu-braunschweig.de/receive/dbbs_mods_00073373
Autor:
Liebmann, Moritz
Die weltweit zunehmende Prävalenz macht den Gestationsdiabetes (GDM) zu einer wachsenden Belastung für die Gesundheitssysteme. Dieser ist als eine erstmals während der Schwangerschaft diagnostizierte Glucosetoleranzstörung (IGT) definiert, wobei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55a838e3562e6d300d74c02ef0620855
Autor:
Demuth, Luisa, Ohm, Melanie, Michaelsen-Preusse, Kristin, Schulze, Kai, Riese, Peggy, Guzmán, Carlos A., Korte, Martin, Hosseini, Shirin
Influenza A virus (IAV) subtypes are a major cause of illness and mortality worldwide and pose a threat to human health. Although IAV infection is considered a self-limiting respiratory syndrome, an expanded spectrum of cerebral manifestations has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::921b232f041bccc8fb12649ccb7ead75
https://leopard.tu-braunschweig.de/servlets/MCRFileNodeServlet/dbbs_derivate_00051888/fphar-14-1142639.pdf
https://leopard.tu-braunschweig.de/servlets/MCRFileNodeServlet/dbbs_derivate_00051888/fphar-14-1142639.pdf
Autor:
Lindhof, Jens Christian
Trypanosoma- und Leishmania-Parasiten lösen verheerende Infektionskrankheiten in den Tropen aus, die von der Weltgesundheitsorganisation zu den vernachlässigten Tropenkrankheiten gezählt werden. Die aktuell zugelassenen Chemotherapeutika erfüllen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::368060b0ae99628d63be1e8ee51e9302