Zobrazeno 1 - 10
of 59
pro vyhledávání: '"dantong sun"'
Autor:
Dantong Sun, Lipin Tan, Yongbing Chen, Qiang Yuan, Kanqiu Jiang, Yangyang Liu, Yuhang Xue, Jinzhi Zhang, Xianbao Cao, Minzhao Xu, Yang Luo, Zhonghua Xu, Zhonghen Xu, Weihua Xu, Mingjing Shen
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-15 (2024)
Abstract Background Lung cancer remains one of the most prevalent cancer types worldwide, with a high mortality rate. Upregulation of programmed cell death protein 1 (PD-1) and its ligand (PD-L1) may represent a key mechanism for evading immune surve
Externí odkaz:
https://doaj.org/article/a5c8c51ef27847c69ee69bbe67c23fcd
Autor:
Hai Zhou, Dantong Sun, Shanai Song, Yurong Niu, Yuming Zhang, Hongwei Lan, Jiali Cui, Houde Liu, Ning Liu, Helei Hou
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Background Immune checkpoint inhibitors (ICIs), especially those targeting programmed cell death-1 (PD-1) and programmed cell death ligand-1 (PD-L1), have introduced a new treatment landscape for many types of tumors. However, they only achi
Externí odkaz:
https://doaj.org/article/bced8f661c30458c8cb8acbead51cd59
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-12 (2024)
Abstract MDM2 has been established as a biomarker indicating poor prognosis for individuals undergoing immune checkpoint inhibitor (ICI) treatment for different malignancies by various pancancer studies. Specifically, patients who have MDM2 amplifica
Externí odkaz:
https://doaj.org/article/59fe2c9011b647189678356b0bd7de4f
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-11 (2024)
Abstract Targeted therapy for malignancies has developed rapidly in recent years, benefiting patients harboring genetic mutations sensitive to relevant tyrosine kinase inhibitors (TKIs). With the development of targeted sequencing techniques, an incr
Externí odkaz:
https://doaj.org/article/2961009cac3b441c8e633c54283c3b3f
Publikováno v:
Cancer Innovation, Vol 2, Iss 3, Pp 210-218 (2023)
Abstract YES proto‐oncogene 1 (YES1) is an SRC family kinase (SFK) that plays a key role in cancer cell proliferation, adhesion, invasion, survival, and angiogenesis during tumorigenesis and tumor development. Reports suggest that YES1 amplificatio
Externí odkaz:
https://doaj.org/article/fca4756009d14c7885f1732360d6769b
Autor:
Dantong Sun, Feiyue Feng, Fei Teng, Tongji Xie, Jinsong Wang, Puyuan Xing, Haili Qian, Junling Li
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Introduction Dysregulated ARID1A expression is frequently detected in lung adenocarcinoma (LUAD) and mediates significant changes in cancer behaviors and a poor prognosis. ARID1A deficiency in LUAD enhances proliferation and metastasis, whic
Externí odkaz:
https://doaj.org/article/b44b859bf4da482ab95281c171696e57
Autor:
Dantong Sun, Weizheng Wu, Li Wang, Jialin Qu, Qiman Han, Huiyun Wang, Shanai Song, Ning Liu, Yongjie Wang, Helei Hou
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-10 (2023)
Abstract Introduction Alterations in the MET gene, including amplifications and exon 14 skipping mutations, have been identified as actionable oncogenic alterations. However, MET fusions are rarely detected in lung cancer, and their sensitivity to th
Externí odkaz:
https://doaj.org/article/2d54b954775848f1adcfe3892c2ff310
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-16 (2022)
Abstract Introduction EGFR mutations in non-small cell lung cancer (NSCLC) are associated with a poor response to immune checkpoint inhibitors (ICIs), and only 20% of NSCLC patients harboring EGFR mutations benefit from immunotherapy. Novel biomarker
Externí odkaz:
https://doaj.org/article/9a8ab563b265415784c3f95e460f70bd
Publikováno v:
Translational Oncology, Vol 33, Iss , Pp 101685- (2023)
Background: ARID1A alterations have been detected in 40% of endometrial carcinomas (ECs) and are associated with loss of its expression. The role of ARID1A in tumorigenesis and development is complex, and the prognostic role in EC remains controversi
Externí odkaz:
https://doaj.org/article/5f588572c17243568452deb1d2e71f15
Publikováno v:
Molecular Medicine, Vol 27, Iss 1, Pp 1-8 (2021)
Abstract ARID1A is a key component of the SWI/SNF chromatin remodeling complexes which is important for the maintaining of biological processes of cells. Recent studies had uncovered the potential role of ARID1A alterations or expression loss in the
Externí odkaz:
https://doaj.org/article/41c7687466ae41a58d537046f5c0be91