Antibiotic-induced disruption of the microbiome exacerbates chemotherapy-induced diarrhoea and can be mitigated with autologous faecal microbiota transplantation

Autor: Wardill, Hannah R., van der Aa, Stijn A.R., da Silva Ferreira, Ana R., Havinga, Rick, Tissing, Wim J.E., Harmsen, Hermie J.M.

Publikováno v: In European Journal of Cancer August 2021 153:27-39

Development of a self-limiting model of methotrexate-induced mucositis reinforces butyrate as a potential therapy.

Autor: da Silva Ferreira, A. R.^1,2 (AUTHOR), van der Aa, S. A. J.^2,3,4 (AUTHOR), Wehkamp, T.^2,4 (AUTHOR), Wardill, H. R.^2,3,5,6 (AUTHOR), ten Klooster, J. P.^2,7 (AUTHOR), Garssen, J.^2,4,7 (AUTHOR), Harthoorn, L. F.^2,4 (AUTHOR), Hartog, A.^2,4 (AUTHOR), Harmsen, H. J. M.^1,2 (AUTHOR) h.j.m.harmsen@umcg.nl, Tissing, W. J. E.^2,3,8 (AUTHOR), van Bergenhenegouwen, J.^2,4,7 (AUTHOR)

Publikováno v: Scientific Reports. 11/25/2021, Vol. 11 Issue 1, p1-11. 11p.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Pre-therapy fasting slows epithelial turnover and modulates the microbiota but fails to mitigate methotrexate-induced gastrointestinal mucositis

Autor: Wardill, H. R., da Silva Ferreira, A. R., Lichtenberg Cloo, S., Havinga, R., Harmsen, H. J. M., Vermeij, W. P., Tissing, W. J. E.

Publikováno v: Gut Microbes; November 2020, Vol. 12 Issue: 1

Supporting the gastrointestinal microenvironment during high-dose chemotherapy and stem cell transplantation by inhibiting IL-1 signaling with anakinra.

Autor: Wardill HR; School of Biomedicine, The University of Adelaide, Adelaide, SA, Australia. hannah.wardill@adelaide.edu.au.; The Supportive Oncology Research Group, Precision Medicine Theme (Cancer), The South Australian Health and Medical Research Institute, Adelaide, SA, Australia. hannah.wardill@adelaide.edu.au.; Department of Pediatrics, The University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. hannah.wardill@adelaide.edu.au., de Mooij CEM; Department of Hematology, Radboud University Medical Center, Nijmegen, The Netherlands., Da Silva Ferreira AR; Department of Medical Microbiology, The University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Havinga H; Department of Pediatrics, The University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Harmsen HJM; Department of Medical Microbiology, The University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., van der Velden WJFM; Department of Hematology, Radboud University Medical Center, Nijmegen, The Netherlands., van Groningen LFJ; Department of Hematology, Radboud University Medical Center, Nijmegen, The Netherlands., Tissing WJE; Department of Pediatrics, The University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; Princes Maxima Center for Pediatric Oncology, Utrecht, The Netherlands., Blijlevens NMA; Department of Hematology, Radboud University Medical Center, Nijmegen, The Netherlands.

Publikováno v: Scientific reports [Sci Rep] 2022 May 11; Vol. 12 (1), pp. 6803. Date of Electronic Publication: 2022 May 11.