Zobrazeno 1 - 10
of 1 005
pro vyhledávání: '"dNTP"'
Publikováno v:
Biology Direct, Vol 19, Iss 1, Pp 1-15 (2024)
Abstract Background Endometrial cancer (EC) presents significant clinical challenges due to its heterogeneity and complex pathophysiology. SAMHD1, known for its role as a deoxynucleotide triphosphate triphosphohydrolase, has been implicated in the pr
Externí odkaz:
https://doaj.org/article/6096e829ab914fcfa1afa9eecc8b480a
Autor:
Miriam Yagüe-Capilla, Sean G. Rudd
Publikováno v:
Disease Models & Mechanisms, Vol 17, Iss 8 (2024)
Externí odkaz:
https://doaj.org/article/a9e5c8a9c2f34d0ea04b807185845130
Publikováno v:
Biomolecules, Vol 14, Iss 8, p 961 (2024)
Human terminal deoxynucleotidyl transferase (TdT) can catalyze template-independent DNA synthesis during the V(D)J recombination and DNA repair through nonhomologous end joining. The capacity for template-independent random addition of nucleotides to
Externí odkaz:
https://doaj.org/article/7de0eb4adcee41ecb55624fd8cc8d8e1
Autor:
Ming-Han C. Tsai, Sarah J. Caswell, Elizabeth R. Morris, Melanie C. Mann, Simon Pennell, Geoff Kelly, Harriet C. T. Groom, Ian A. Taylor, Kate N. Bishop
Publikováno v:
Retrovirology, Vol 20, Iss 1, Pp 1-18 (2023)
Abstract Background SAMHD1 is a deoxynucleotide triphosphohydrolase that restricts replication of HIV-1 in differentiated leucocytes. HIV-1 is not restricted in cycling cells and it has been proposed that this is due to phosphorylation of SAMHD1 at T
Externí odkaz:
https://doaj.org/article/fcc2447b7cb84ebfa5ff96be2eb62e0d
Autor:
Éva Viola Surányi, Viktória Perey-Simon, Rita Hirmondó, Tamás Trombitás, Latifa Kazzazy, Máté Varga, Beáta G. Vértessy, Judit Tóth
Publikováno v:
Biomolecules, Vol 13, Iss 12, p 1801 (2023)
Cells maintain a fine-tuned balance of deoxyribonucleoside 5′-triphosphates (dNTPs), a crucial factor in preserving genomic integrity. Any alterations in the nucleotide pool’s composition or chemical modifications to nucleotides before their inco
Externí odkaz:
https://doaj.org/article/246eae099bce49ec94da410c7a84d56b
Autor:
Thomas Helleday, Sean G. Rudd
Publikováno v:
Molecular Oncology, Vol 16, Iss 21, Pp 3792-3810 (2022)
The exploitation of the DNA damage response and DNA repair proficiency of cancer cells is an important anticancer strategy. The replication and repair of DNA are dependent upon the supply of deoxynucleoside triphosphate (dNTP) building blocks, which
Externí odkaz:
https://doaj.org/article/34eb11aac058474dbfa1c1a3d29fe6b5
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Jichu yixue yu linchuang, Vol 41, Iss 11, Pp 1666-1670 (2021)
Deoxycytidine triphosphate pyrophosphatase 1(dCTP pyrophosphatase 1, DCTPP1) is a newly discovered pyrophosphatase targeting deoxycytidine triphosphate (dCTP). It regulates cytosine metabolism by not only hydrolyzing conventional and modified dCTP, b
Externí odkaz:
https://doaj.org/article/0aca5338ef47476ba8ec85594f062f16