Maternal High-Protein and Low-Protein Diets Perturb Hypothalamus and Liver Transcriptome and Metabolic Homeostasis in Adult Mouse Offspring

Autor: Lisa J. Martin, Qingying Meng, Montgomery Blencowe, Sandrine Lagarrigue, Sheila Xiao, Calvin Pan, Julian Wier, William C. Temple, Sherin U. Devaskar, Aldons J. Lusis, Xia Yang

Publikováno v: Frontiers in Genetics
Frontiers in Genetics, Frontiers, 2018, 9, ⟨10.3389/fgene.2018.00642⟩
Frontiers in Genetics (9), . (2018)
Frontiers in Genetics, Vol 9 (2018)

Early life nutritional imbalances are risk factors for metabolic dysfunctions in adulthood, but the long term effects of perinatal exposure to high versus low protein diets are not completely understood. We exposed C57BL/6J offspring to a high protei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1006ad46d280cdf1d75bceeb89437eb6
https://doi.org/10.3389/fgene.2018.00642

Changes in body composition and metabolic profile during interleukin 6 inhibition in rheumatoid arthritis

Autor: Pereira, Bruno, Dutheil, Fréderic, Giraud, Charlotte, Courteix, Daniel, Sapin, Vincent, Frayssac, Thomas, Mathieu, Sylvain, Malochet-Guinamand, Sandrine, Soubrier, Martin

Publikováno v: Journal of Cachexia, Sarcopenia and Muscle 4 (8), 639-646. (2017)

BACKGROUND: Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by increased mortality associated with cardiometabolic disorders including dyslipidaemia, insulin resistance, and cachectic obesity. Tumour necrosis factor inhibito

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1582::ae0a6995bd7f501301c73036477fa166
http://prodinra.inra.fr/record/390353

Metabolomics as a new key actor in systems biology for better understanding nutrition-health relationship

Autor: Pujos-Guillot, Estelle, Petera, Mélanie, Brandolini-Bunlon, Marion, Liu, Yunfei, Giacomoni, Franck, Comte, Blandine

Publikováno v: 8. Santorini Conference "Systems Medicine, personalised health and therapy"
8. Santorini Conference "Systems Medicine, personalised health and therapy", Oct 2016, Thira-Santorini, Greece. 2016
1. Conference of the European Association of Systems Medicine (EASyM)
1. Conference of the European Association of Systems Medicine (EASyM), Oct 2016, Berlin, Germany. 223 p., 2016, First Conference of the European Association of Systems Medicine-conference programme
8. Santorini Conference "Systems Medicine, personalised health and therapy", Oct 2016, Thira-Santorini, Greece., 2016
1. Conference of the European Association of Systems Medicine (EASyM), Oct 2016, Berlin, Germany. 223 p., 2016

International audience; Background: Human body responses to nutrition and chronic metabolic disorders represent complex features that require integrated systems biology approach to better understand their relationship. Metabolomics, as a powerful phe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d924e626c887187ad1d5e7f440224bbb
https://hal.inrae.fr/hal-02740744

Influence d’un régime hypercalorique maternel et post-sevrage sur l’état métabolique de la descendance. Implication de l’activité mitochondriale et de la méthylation de l’ADN

Autor: Wrutniak-Cabello, Chantal

Publikováno v: 2. Réunion d'Animation épiPHASE
2. Réunion d'Animation épiPHASE, Institut National de Recherche Agronomique (INRA). UAR Département Physiologie Animale et Systèmes d'Elevage (0558)., Mar 2016, Saint-Pée-sur-Nivelle, France
2. Réunion d'Animation épiPHASE, Mar 2016, Saint-Pée-sur-Nivelle, France

La consommation maternelle d'une alimentation déséquilibrée pendant la gestation induit non seulement obésité et diabète de type 2 chez les mères, mais également des désordres métaboliques de longue durée chez leur descendance. Les mitocho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::88bb1f01cf1b4b227c2f72330bd3d525
https://hal.archives-ouvertes.fr/hal-01837645

Metabolism of bile acids in the post-prandial state

Autor: Fiamoncini, Jarlei, Curi, Rui, Daniel, Hannelore

Publikováno v: Metabolomics and Lipidomics in Nutrition and Metabolism Research
Metabolomics and Lipidomics in Nutrition and Metabolism Research, 60, Portland Press, 2016, Essays in Biochemistry, 978-1-85578-204-4. ⟨10.1042/ebc20160052⟩
Metabolomics and Lipidomics in Nutrition and Metabolism Research, 60, Portland Press, 2016, Essays in Biochemistry, 978-1-85578-204-4 ⟨10.1042/ebc20160052⟩

PubMed: 27980090; The modulation of energy expenditure by dietary administration of cholic acid in mice promoted interest in studying bile acid(s) (BA) as adjuvants in the treatment of metabolic diseases such as obesity and diabetes. Bile acids can m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::72bb4b3b749b50bc5b7a7d06fac81ad7
https://hal.archives-ouvertes.fr/hal-01575934