Zobrazeno 1 - 10
of 3 206
pro vyhledávání: '"cytotrophoblast"'
Publikováno v:
PeerJ, Vol 12, p e18227 (2024)
Background As one of the most common and abundant internal modifications of eukaryotic mRNA, N6-methyladenosine (m6A) modifications are closely related to placental development. Ferroptosis is a newly discovered form of programmed cell death. During
Externí odkaz:
https://doaj.org/article/f977bf36bb124dc8a54466ee33271fcd
Autor:
Rafaela J. da Silva, Leah F. Cabo, Jada L. George, Laty A. Cahoon, Liheng Yang, Carolyn B. Coyne, Jon P. Boyle
Publikováno v:
mSphere, Vol 9, Iss 6 (2024)
ABSTRACT The placenta is a critical barrier against viral, bacterial, and eukaryotic pathogens. For most teratogenic pathogens, the precise molecular mechanisms of placental resistance are still being unraveled. Given the importance of understanding
Externí odkaz:
https://doaj.org/article/a82f1a3d2b6545439bca76c37e1aa2d1
Autor:
Ahmed F. Pantho, Sara Mohamed, Janhavi V. Govande, Riddhi Rane, Niraj Vora, Kelsey R. Kelso, Thomas J. Kuehl, Steven R. Lindheim, Mohammad N. Uddin
Publikováno v:
Cells, Vol 13, Iss 18, p 1534 (2024)
There are no effective therapies to prevent preeclampsia (PE). Pravastatin shows promise by attenuating processes associated with PE such as decreased cytotrophoblast (CTB) migration, aberrant angiogenesis, and increased oxidative stress. This study
Externí odkaz:
https://doaj.org/article/4dc79c0ac4aa44208a3500ba676c9a50
Publikováno v:
Microorganisms, Vol 12, Iss 8, p 1640 (2024)
Malaria during pregnancy has been associated with significant risks to both the mother and the fetus, leading to complications such as anemia, low birth weight, and increased infant mortality. The trophoblast cells, a key component of the placenta, a
Externí odkaz:
https://doaj.org/article/57c2d1d68e8d4bec9b086da0680cd9a3
Autor:
Giovanni Tossetta, Sonia Fantone, Stefano Raffaele Giannubilo, Andrea Ciavattini, Martina Senzacqua, Andrea Frontini, Daniela Marzioni
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 5, Pp 3815-3828 (2023)
The HtrA serine peptidase 1 (HTRA1) is a multidomain secretory protein with serine–protease activity involved in the regulation of many cellular processes in both physiological and pathological conditions. HTRA1 is normally expressed in the human p
Externí odkaz:
https://doaj.org/article/24175ee509794664871b9d1b2dab0a79
Autor:
Mercedes Viettri, Gerson Caraballo, Maria Elena Sanchez, Aurora Espejel-Nuñez, Abigail Betanzos, Vianney Ortiz-Navarrete, Guadalupe Estrada-Gutierrez, Porfirio Nava, Juan E. Ludert
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT The Zika virus (ZIKV) is teratogenic and considered a TORCH pathogen (toxoplasmosis [Toxoplasma gondii], rubella, cytomegalovirus, herpes simplex virus [HSV], and other microorganisms capable of crossing the blood-placenta barrier). In contr
Externí odkaz:
https://doaj.org/article/8b234084223e4191ab992cc76994e4dd
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Autor:
Sereen K. Nashif, Renee M. Mahr, Snehalata Jena, Seokwon Jo, Alisa B. Nelson, Danielle Sadowski, Peter A. Crawford, Patrycja Puchalska, Emilyn U. Alejandro, Micah D. Gearhart, Sarah A. Wernimont
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Metformin is a widely prescribed medication whose mechanism of action is not completely defined and whose role in gestational diabetes management remains controversial. In addition to increasing the risk of fetal growth abnormalities and preeclampsia
Externí odkaz:
https://doaj.org/article/ec144421216f40e890797827bc132634