Zobrazeno 1 - 10
of 10 335
pro vyhledávání: '"cytotoxic t-lymphocytes"'
Autor:
Martina Cimerman, Natalia Druzhaeva, Alenka Nemec Svete, Melita Hajdinjak, Katka Pohar, Alojz Ihan, Aleksandra Domanjko Petrič
Publikováno v:
BMC Veterinary Research, Vol 20, Iss 1, Pp 1-15 (2024)
Abstract Background We aimed to investigate the association between selected inflammatory and immune variables and survival of dogs with myxomatous mitral valve disease (MMVD). We evaluated data of 62 client-owned dogs with MMVD, grouped into preclin
Externí odkaz:
https://doaj.org/article/11c02294e48744f38a46c6dff32cfcd1
Autor:
Chih-Hao Fang, Ya Fang Cheng, Shian-Ren Lin, Wan-Yu Lai, Li-Ren Liao, Yen-Ling Chiu, Jan-Mou Lee
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Lytic Epstein–Barr virus (EBV) infection plays a major role in the pathogenesis of nasopharyngeal carcinoma (NPC). For patients with recurrent or metastatic NPC and resistant to conventional therapies, adoptive cell therapy usin
Externí odkaz:
https://doaj.org/article/228dd9d1e6fe49869158254df1b7702b
Publikováno v:
Annals of Clinical Microbiology and Antimicrobials, Vol 23, Iss 1, Pp 1-11 (2024)
Abstract Objectives The aim of this study was to evaluate the characteristics of immunocyte associated with bloodstream infection (BSI) caused by Klebsiella pneumoniae (Kpn). Methods Patients with BSI-Kpn were included from 2015 to 2022 in our hospit
Externí odkaz:
https://doaj.org/article/ed992cb86f684b6d8ea042d1501ce69d
Publikováno v:
Open Medicine, Vol 19, Iss 1, Pp 620-32 (2024)
Immune thrombocytopenia (ITP) is an autoimmune disease characterized by a low platelet (PLT) count and a high risk of bleeding, the clinical treatment for which still needs to be upgraded. Based on the critical role of human leukocyte antigen class I
Externí odkaz:
https://doaj.org/article/c14fb05322ea44509668a9c30c488d0c
Autor:
Brandon C. Rosen, Kaitlin Sawatzki, Michael J. Ricciardi, Elise Smith, Inah Golez, Jack T. Mauter, Núria Pedreño-López, Aaron Yrizarry-Medina, Kim L. Weisgrau, Logan J. Vosler, Thomas B. Voigt, Johan J. Louw, Jennifer Tisoncik-Go, Leanne S. Whitmore, Christakis Panayiotou, Noor Ghosh, Jessica R. Furlott, Christopher L. Parks, Ronald C. Desrosiers, Jeffrey D. Lifson, Eva G. Rakasz, David I. Watkins, Michael Gale
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionSpontaneous control of chronic-phase HIV/SIV viremia is often associated with the expression of specific MHC class I allotypes. HIV/SIV-specific CD8+ cytotoxic T lymphocytes (CTLs) restricted by these MHC class I allotypes appear to be cr
Externí odkaz:
https://doaj.org/article/a278c58415384153962a8239ac4c5dc6
Autor:
Shasha Deng, Zhihao Xu, Jing Hu, Yunru Yang, Fang Zhu, Zhuan Liu, Hongliang Zhang, Songquan Wu, Tengchuan Jin
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Cytotoxic CD8+ T lymphocytes (CTLs) have been implicated in the severity of COVID-19. The TCR-pMHC ternary complex, formed by the T cell receptor (TCR) and peptide-MHC (major histocompatibility complex), constitutes the molecular basis of CTL respons
Externí odkaz:
https://doaj.org/article/cb3aab4ce4d94754899f8b5f713c1626
Autor:
Xian An, Zhuang Chen, Yi Luo, Peng Yang, Zuo Yang, Tiannan Ji, Yajing Chi, Shuyuan Wang, Ruili Zhang, Zhongliang Wang, Jianxiong Li
Publikováno v:
Advanced Science, Vol 11, Iss 33, Pp n/a-n/a (2024)
Abstract In situ cancer vaccination is an attractive strategy that stimulates protective antitumor immunity. Cytotoxic T lymphocytes (CTLs) are major mediators of the adaptive immune defenses, with critical roles in antitumor immune response and esta
Externí odkaz:
https://doaj.org/article/2fe4428658524d7f8f2e11fec365f49f
Autor:
Xiaoqian Chen, Wenkui Li, Xiaogai Lei, Zhanhong Li, Qijing Guo, Xinfu Ma, Yushuang Luo, Liang Wang
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
ObjectiveTo investigate the effects of a PD-1 inhibitor combined with a bevacizumab monoclonal antibody on tumor immune cells in patients with first-line treatment failure in MSS/pMMR advanced colorectal cancer.MethodsControl group consisted of 50 pa
Externí odkaz:
https://doaj.org/article/573023f8609c495f8be0a9b1f7e99515
Autor:
Shengkun Peng, Anqi Lin, Aimin Jiang, Cangang Zhang, Jian Zhang, Quan Cheng, Peng Luo, Yifeng Bai
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-19 (2024)
Abstract Cytotoxic T lymphocytes (CTLs) play critical antitumor roles, encompassing diverse subsets including CD4+, NK, and γδ T cells beyond conventional CD8+ CTLs. However, definitive CTLs biomarkers remain elusive, as cytotoxicity-molecule expre
Externí odkaz:
https://doaj.org/article/96dffe7c77344b3a81f5b751168894a0
Autor:
Obed Boadi Amissah, Wenfang Chen, Jean de Dieu Habimana, Yirong Sun, Lihui Lin, Yujie Liu, Ling Wang, Zhaoming Liu, Omar Mukama, Rajesh Basnet, Hohua Liu, Junyi Li, Xuanyan Ding, Lingshuang Lv, Min Chen, Yalin Liang, Rongqi Huang, Zhiyuan Li
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-18 (2024)
Abstract Background Esophageal cancer (EC) is a global canker notorious for causing high mortality due to its relentless incidence rate, convoluted with unyielding recurrence and metastasis. However, these intricacies of EC are associated with an imm
Externí odkaz:
https://doaj.org/article/18ff037bbc2044b898ab952d16040a0f