Trehalose itself plays a critical role on lipid metabolism: Trehalose increases jejunum cytoplasmic lipid droplets which negatively correlated with mesenteric adipocyte size in both HFD-fed trehalase KO and WT mice

Autor: Chikako Arai, Aki Suyama, Shigeyuki Arai, Norie Arai, Chiyo Yoshizane, Satomi Koya-Miyata, Akiko Mizote, Shin Endo, Toshio Ariyasu, Hitoshi Mitsuzumi, Shimpei Ushio

Publikováno v: Nutrition & Metabolism, Vol 17, Iss 1, Pp 1-12 (2020)

Abstract Background Trehalose is a functional disaccharide that has anti-metabolic activities such as suppression of adipocyte hypertrophy in mice and alleviation of impaired glucose tolerance in humans. Trehalase hydrolyzes trehalose in the small in

Externí odkaz: https://doaj.org/article/1c4067d1957f45ce8aa1a82f05ff8ef0

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Trehalose itself plays a critical role on lipid metabolism: Trehalose increases jejunum cytoplasmic lipid droplets which negatively correlated with mesenteric adipocyte size in both HFD-fed trehalase KO and WT mice

Autor: Hitoshi Mitsuzumi, Norie Arai, Shigeyuki Arai, Akiko Mizote, Shin Endo, Chiyo Yoshizane, Shimpei Ushio, Satomi Koya-Miyata, Chikako Arai, Aki Suyama, Toshio Ariyasu

Publikováno v: Nutrition & Metabolism, Vol 17, Iss 1, Pp 1-12 (2020)
Nutrition & Metabolism

Background Trehalose is a functional disaccharide that has anti-metabolic activities such as suppression of adipocyte hypertrophy in mice and alleviation of impaired glucose tolerance in humans. Trehalase hydrolyzes trehalose in the small intestine i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfe64de72ab9ef067cddb5eb5e65d3ce
http://link.springer.com/article/10.1186/s12986-020-00443-1

Oral Glucose Mobilizes Triglyceride Stores From the Human Intestine

Autor: Ian Bookman, Kimberly K. Buhman, Priska Stahel, Gary F. Lewis, Changting Xiao, Yu-Han Hung, Alicia L. Carreiro, Satya Dash

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 2, Pp 313-337 (2019)
Cellular and Molecular Gastroenterology and Hepatology

Background & Aims The small intestine regulates plasma triglyceride (TG) concentration. Within enterocytes, dietary TGs are packaged into chylomicrons (CMs) for secretion or stored temporarily in cytoplasmic lipid droplets (CLDs) until further mobili

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::343b753e0a8b8eebe9dc702640d79aaf
https://doi.org/10.1016/j.jcmgh.2018.10.002

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