Zobrazeno 1 - 10
of 40
pro vyhledávání: '"cytology [Neural Stem Cells]"'
Autor:
Lena Wischhof, Hang‐Mao Lee, Janine Tutas, Clemens Overkott, Eileen Tedt, Miriam Stork, Michael Peitz, Oliver Brüstle, Thomas Ulas, Kristian Händler, Joachim L Schultze, Dan Ehninger, Pierluigi Nicotera, Paolo Salomoni, Daniele Bano
Publikováno v:
The EMBO journal 41(23), e110595 (2022). doi:10.15252/embj.2022110595
Mammalian SWI/SNF/BAF chromatin remodeling complexes influence cell lineage determination. While the contribution of these complexes to neural progenitor cell (NPC) proliferation and differentiation has been reported, little is known about the transc
Autor:
Kai F. Loewenbrück, Moritz D. Brandt, Johannes Rangnick, Andreas Hermann, Alexander Storch, Mareike Fauser
Publikováno v:
Cells
Cells, Vol 10, Iss 3021, p 3021 (2021)
Volume 10
Issue 11
Cells 10(11), 3021 (2021). doi:10.3390/cells10113021
Cells, Vol 10, Iss 3021, p 3021 (2021)
Volume 10
Issue 11
Cells 10(11), 3021 (2021). doi:10.3390/cells10113021
The regulation of adult neural stem or progenitor cell (aNSC) proliferation and differentiation as an interplay of cell-intrinsic and local environmental cues remains in part unclear, impeding their role in putative regenerative therapies. aNSCs with
Autor:
Ben Wielockx, Gerd Kempermann, Tara L. Walker, Suse Seidemann, Sonja Schallenberg, Odette Leiter, Tatyana Grinenko, Beáta Ramasz, Nicole Rund, Rupert W. Overall
Publikováno v:
Stem Cell Reports, Vol 12, Iss 4, Pp 667-679 (2019)
Stem cell reports 12(4), 667-679 (2019). doi:10.1016/j.stemcr.2019.02.009
Stem Cell Reports
Stem cell reports 12(4), 667-679 (2019). doi:10.1016/j.stemcr.2019.02.009
Stem Cell Reports
Summary Physical activity is a strong positive physiological modulator of adult neurogenesis in the hippocampal dentate gyrus. Although the underlying regulatory mechanisms are still unknown, systemic processes must be involved. Here we show that pla
Generation of mouse hippocampal neural precursor cell lines with CRISPR/Cas9-mediated gene knockouts
Autor:
Sara Zocher, Gerd Kempermann
Publikováno v:
STAR Protocols 2(2), 100472 (2021). doi:10.1016/j.xpro.2021.100472
STAR Protocols, Vol 2, Iss 2, Pp 100472-(2021)
STAR Protocols
STAR Protocols, Vol 2, Iss 2, Pp 100472-(2021)
STAR Protocols
Summary Genetic manipulation of neural precursor cells is an important tool to study mechanisms underlying proliferation, fate specification, and neuron formation. The CRISPR/Cas9 system enables efficient genome editing but requires the clonal expans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89a0e3899678ef2f4de92b850c873023
Autor:
Pedro Belio-Mairal, Emmanuel Nivet, Laurie Arnaud, Alexander Dityatev, Santiago Rivera, Nikita Arnst, Laura García-González, Louise Greetham
Publikováno v:
Cells
Cells, 2021, 10 (7), pp.1705. ⟨10.3390/cells10071705⟩
Volume 10
Issue 7
Cells, Vol 10, Iss 1705, p 1705 (2021)
Cells 10(7), 1705 (2021). doi:10.3390/cells10071705 special issue: "Pluripotent Stem Cells for Regenerative Medicine"
Cells, MDPI, 2021, 10 (7), pp.1705. ⟨10.3390/cells10071705⟩
Cells, 2021, 10 (7), pp.1705. ⟨10.3390/cells10071705⟩
Volume 10
Issue 7
Cells, Vol 10, Iss 1705, p 1705 (2021)
Cells 10(7), 1705 (2021). doi:10.3390/cells10071705 special issue: "Pluripotent Stem Cells for Regenerative Medicine"
Cells, MDPI, 2021, 10 (7), pp.1705. ⟨10.3390/cells10071705⟩
International audience; For some time, it has been accepted that the β-site APP cleaving enzyme 1 (BACE1) and the γ-secretase are two main players in the amyloidogenic processing of the β-amyloid precursor protein (APP). Recently, the membrane-typ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7770ce90448455c7c181fcd8dbf6931e
https://hal.science/hal-03423990
https://hal.science/hal-03423990
Autor:
András Simon, Andrea Pedroni, Caghan Kizil, Maria Bertuzzi, Konstantinos Ampatzis, Weipang Chang
Publikováno v:
Nature Communications
Nature Communications 12(1), 4857 (2021). doi:10.1038/s41467-021-25052-1
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications 12(1), 4857 (2021). doi:10.1038/s41467-021-25052-1
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Physical exercise stimulates adult neurogenesis, yet the underlying mechanisms remain poorly understood. A fundamental component of the innate neuroregenerative capacity of zebrafish is the proliferative and neurogenic ability of the neural stem/prog
Autor:
Danielyan, Lusine, Schwab, Matthias, Krueger, Marcel A., Calaminus, Carsten, Naumann, Ulrike, Winter, Stefan, Schaeffeler, Elke, Spogis, Annett, Beer-Hammer, Sandra, Neher, Jonas J., Spohn, Gabriele, Kretschmer, Anja, Siegel, Georg, Krämer-Albers, Eva-Maria, Barth, Kerstin, Lee, Hong Jun, Kim, Seung U., Frey, William H., Claussen, Claus D., Hermann, Dirk M., Doeppner, Thorsten R., Seifried, Erhard, Gleiter, Christoph H., Brawek, Bianca, Northoff, Hinnak, Schäfer, Richard, Garaschuk, Olga, Asavapanumas, Nithi, Buadze, Marine, Lourhmati, Ali, Wendel, Hans-Peter, Avci-Adali, Meltem
Publikováno v:
EBioMedicine, Vol 60, Iss, Pp 102989-(2020)
EBioMedicine
EBioMedicine 60, 102989-(2020). doi:10.1016/j.ebiom.2020.102989
EBioMedicine
EBioMedicine 60, 102989-(2020). doi:10.1016/j.ebiom.2020.102989
Background: Stem cells‘ (SC) functional heterogeneity and its poorly understood aetiology impedes clinical development of cell-based therapies in regenerative medicine and oncology. Recent studies suggest a strong correlation between the SC migrati
Autor:
Yuanbin Xie, Linh Pham, Gregor Eichele, Andre Fischer, Cemil Kerimoglu, Xiaoyi Mao, Huu Phuc Nguyen, Joachim Rosenbusch, Jochen F. Staiger, Peter Ditte, Ulrike Teichmann, Pauline Antonie Ulmke, Godwin Sokpor, Tran Tuoc, M. Sadman Sakib
Publikováno v:
Stem Cell Reports
Stem cell reports 16(4), 968-984 (2021). doi:10.1016/j.stemcr.2021.03.008
Stem cell reports 16(4), 968-984 (2021). doi:10.1016/j.stemcr.2021.03.008
Summary Intermediate progenitor cells (IPCs) are neocortical neuronal precursors. Although IPCs play crucial roles in corticogenesis, their molecular features remain largely unknown. In this study, we aimed to characterize the molecular profile of IP
Autor:
Eldem Sadikoglou, Joachim Täger, Manmeet-Sakshi Bedi, Noemia Fernandes, Stefanie Bröer, Peter Heutink, Salvador Rodriguez-Nieto, Ashutosh Dhingra, Patrizia Rizzu, Elisangela Bressan, Melissa Castillo-Lizardo
Publikováno v:
JoVE journal Biology(162), 61525 (2020). doi:10.3791/61525
Manual culture and differentiation protocols for human induced pluripotent stem cells (hiPSC) are difficult to standardize, show high variability and are prone to spontaneous differentiation into unwanted cell types. The methods are labor-intensive a
Autor:
Mareike Fauser, Moritz D. Brandt, Christoph Redecker, Manfred Gerlach, Julia Müller, Grit Weselek, Silke Keiner, Alexander Storch, Barbara Kaltschmidt, Andreas Hermann, Lisa Wagenführ
Publikováno v:
Stem cells 38(9), 1188–1201 (2020). doi:10.1002/stem.3232
The limited proliferative capacity of neuroprogenitor cells (NPCs) within the periventricular germinal niches (PGNs) located caudal of the subventricular zone (SVZ) of the lateral ventricles together with their high proliferation capacity after isola
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43bdb3622839b7f3f271c955a5ab8d94
https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/21825
https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/21825